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Active clinical trials for "Toothache"

Results 51-60 of 89

Single Dose Study of N1539 in the Treatment of Pain Secondary to Dental Impaction Surgery

Dental Pain

To evaluate the safety and efficacy of single IV doses of N1539 after dental impaction surgery.

Completed10 enrollment criteria

CBD for Dental Pain

OdontalgiaToothache

The purpose of this study is to evaulate CBD as a therapeutic approach for dental pain. Eligible subjects presented with emergency dental pain will be give a single dose of Epidiolex (FDA-approved CBD) or placebo and will be monitored for 3 hours for pain symptoms and psychologic effects.

Completed11 enrollment criteria

Study of Long-Acting Acetaminophen in Postoperative Dental Pain

Dental Pain

The purpose of the study is to evaluate the efficacy and safety of acetaminophen ER 1500 mg (two 750 mg tablets) over 10 to 12 hours in the dental pain model following third molar extraction(s) and to evaluate the pharmacokinetics of acetaminophen ER 1500 mg (two 750 mg tablets) in a sub-group of subjects.

Completed8 enrollment criteria

A Dental Pain Study to Test the Effectiveness of a New Pain Reliever Medicine

Pain

To assess the safety and effectiveness one dose of a new pain reliever medicine (JNJ-10450232 at either the 250 or 1000 mg strength) compared with placebo (sugar pill) or acetaminophen 1000 mg after surgical removal of third molars. The primary endpoint will evaluate pain relief effectiveness up to 6 hours after administration of the study drug.

Completed5 enrollment criteria

Study of Acetaminophen (ACM) in Post-operative Dental Pain

Post Operative Dental Pain

This is a Dental Pain Study which will evaluate the analgesic onset, efficacy and safety of 1000 mg acetaminophen as two Test acetaminophen 500 mg tablets, compared with commercial products of acetaminophen 1000 mg administered as two 500 mg caplets, and ibuprofen (IBU) 400 mg following third molar (wisdom tooth) extraction.

Completed9 enrollment criteria

Study Evaluating A Novel Ibuprofen Formulation In The Treatment Of Dental Pain

Pain

This study will compare the pain relieving effect of a single-dose of a novel ibuprofen formulation to placebo and two formulations of standard ibuprofen in the treatment of post-surgical dental pain following "wisdom" tooth (third molar) removal.

Completed8 enrollment criteria

Safety and Efficacy Study of XPF-001 to Treat Pain Following Wisdom Tooth Extraction

Dental Pain

The purpose of this trial is to determine if XPF-001 is effective for the treatment of pain following third-molar/wisdom tooth extraction.

Completed31 enrollment criteria

Phase 2 Study of Indomethacin Capsules to Treat Dental Pain

Dental Pain

The purpose of this study is to determine whether Indomethacin Test Formulation Capsules are safe and effective for the treatment of dental pain.

Completed9 enrollment criteria

SB-705498 Dental Pain Study After Tooth Extraction

Toothache

This clinical trial is a multi centre, randomised, single-blind, parallel group, placebo-controlled, single oral dose study with a positive control arm. Patients previously scheduled for 3rd molar tooth extraction, who are otherwise healthy, will be recruited. Upon completion of surgery, e.g. prior to established pain, patients will be randomised to treatment (SB-706598, placebo or co-codamol) and dosed with the study medication

Completed29 enrollment criteria

A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-181)(COMPLETED)...

Postoperative Pain

The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.

Completed2 enrollment criteria
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