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Active clinical trials for "Glaucoma, Open-Angle"

Results 101-110 of 814

Safety and Feasibility of the ELIOS System in POAG Patients

GlaucomaPrimary Open Angle

Evaluation of the safety and effectiveness of the ELIOS System procedure to reduce intraocular pressure (IOP) in adult subjects with mild to moderate primary open-angle glaucoma (POAG)

Not yet recruiting9 enrollment criteria

The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patients...

GlaucomaGlaucoma6 more

Glaucoma represents a group of conditions that cause damage to the optic nerve and can lead to irreversible vision loss. Current treatments are aimed at lowering intraocular pressure while minimizing medication side effects. Lumify™ (Brimonidine Tartrate Ophthalmic Solution 0.025%) is an FDA-approved medication for alleviating eye redness, a common side effect of glaucoma medications. The purpose of this study is to evaluate the effect of Lumify™ on eye redness, intraocular pressure, and eyelid position in patients with glaucoma who are already using the Brimonidine 0.1%, 0.15% or 0.2% eye drops.

Not yet recruiting12 enrollment criteria

Regulation of Intraocular Pressure in Glaucoma Patients by Acupressure

Primary Open Angle GlaucomaAcupressure

The purpose of this clinical trial is to implement acupressure twice daily and monitor the changes in intraocular pressure (IOP) in patients with different levels of glaucoma. The study aims to investigate the effects of this method on IOP, visual field, retinal nerve fiber layer thickness measured by optical coherence tomography, blood vessel density, and macular ganglion cell layer thickness and density in patients with primary open-angle glaucoma (POAG).

Not yet recruiting2 enrollment criteria

Exercise Intervention in Primary Open-angle Glaucoma

GlaucomaOpen-Angle1 more

EYE-FIT is a randomized clinical trial with a two-arm parallel design aimed at assessing the impact of performing a structured and supervised physical training program on the different variables associated with glaucoma progression in pharmacologically treated primary open angle glaucoma patients. This intervention will include a supervised 24-weeks concurrent (endurance + resistance) training program comparing its influence to the standard care.

Not yet recruiting7 enrollment criteria

Efficacy of the Nanodropper Device on Intraocular Pressure in Patients With Glaucoma

GlaucomaOcular Hypertension1 more

Glaucoma is the leading cause of irreversible blindness worldwide. Previous studies demonstrate that smaller eye drops used in the treatment of glaucoma are just as efficacious as their larger counterparts. The proposed study hopes to demonstrate the non-inferiority of using Nanodropper to lower intraoccular pressure (IOP) in glaucoma patients compared to standard of care eye drops.

Recruiting8 enrollment criteria

Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study

Primary Open Angle Glaucoma

The objective of this study is to determine if a combination of oral nicotinamide and pyruvate (N&P) can maintain eye health as compared to placebo while standard-of-care intraocular pressure-lowering glaucoma medications are used to treat glaucoma. A total of up to 188 participants will be enrolled and randomized 1:1 to receive N&P or placebo for 87 weeks (20 months). Participants will be followed for a total of 91 weeks (21 months).

Recruiting21 enrollment criteria

Retinal Photoreceptor Outer Segment Length Before and After Light Stimulation - a Pilot Study

Macular DegenerationDry1 more

It has been shown that reactions of human retinal photoreceptors to a light stimulus can be measured with custom-made, research prototype optical coherence tomography (OCT) systems. This can be used as a biomarker for the function of the photoreceptors. Due to the high technical demands on the system, however, the technique is currently not available for clinical purposes. In this pilot study a protocol to measure changes in retinal photoreceptor layer thickness before and after light stimulation shall be developed based on a commercial OCT system and newly developed algorithms. Other variables, such as circadian processes shall be investigated as well. After measurements in healthy volunteers, the protocol is planned to be applied in patients with primary open angle glaucoma (POAG) and age-related macular degeneration (AMD) to test for feasibility of the method in these patient groups.

Recruiting20 enrollment criteria

Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary...

Glaucoma

There is increasing evidence that there are genetic risk factors for several forms of glaucoma, such as glaucoma caused by pseudoexfoliation syndrome (PXF) ,primary angle closure glaucoma (PACG) and primary open-angle glaucoma (POAG). The aim of the present prospective, multi-center, case-control study is to identify susceptibility genes/loci for PXF, PACG and POAG using a whole genome association (WGA) approach.

Recruiting23 enrollment criteria

Long-term Safety and Performance of the ARGOS-SC Suprachoroidal Pressure Sensor System in Patients...

GlaucomaOpen Angle Glaucoma

The purpose of this study is to evaluate the long-term safety and performance of the ARGOS-SC system.

Active2 enrollment criteria

STAR-LIFE: a Post-market Registry on MINIject

Open Angle Glaucoma

As part of the post-market clinical follow-up (PMCF), this registry is developed to ensure real-world data collection on MINIject device.

Recruiting7 enrollment criteria
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