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Active clinical trials for "Glaucoma, Open-Angle"

Results 71-80 of 814

Clinical Study Comparing Two Models of a Travoprost Intraocular Implant

GlaucomaOpen-Angle1 more

Phase III study to compare the safety and efficacy of intraocular implants containing Travoprost at two different elution rates versus Timolol Maleate Ophthalmic Solution, 0.5% (Timolol) in reducing elevated intraocular pressure in subjects with open angle glaucoma (OAG) or ocular hypertension (OHT)

Active5 enrollment criteria

Optimal Treatment Protocol for Selective Laser Trabeculoplasty

GlaucomaOpen-Angle2 more

A randomized controlled trial to evaluate which treatment protocol in selective laser trabeculoplasty that is most optimal in terms of efficacy and safety.

Active11 enrollment criteria

Study of a Novel Interposition Supraciliary Implant in Patients With Open Angle Glaucoma (SAFARI...

GlaucomaOpen-Angle

The purpose of this study is to evaluate the safety and effectiveness of implanting 2 novel interposition supraciliary implant as a stand-alone therapy for lowering intraocular pressure (IOP) in patients with primary open angle glaucoma (POAG) who have failed at least one class of topical medical therapy

Active3 enrollment criteria

Safety and Efficacy Study of JV-GL1 in Patients With Open-Angle Glaucoma or Ocular Hypertension...

Ocular HypertensionOpen Angle Glaucoma

The aim of this research study is to assess the safety and feasibility of lowering intraocular pressure (IOP) using an experimental study drug, JV-GL1.

Active2 enrollment criteria

MINIject (MINI SO627) in Patients With Open Angle Glaucoma Using Single Operator Delivery Tool

GlaucomaOpen-Angle Glaucoma Eye

The study will assess safety and performance in patients with open-angle glaucoma uncontrolled by topical hypotensive medications who had previously been implanted with a MINIject glaucoma implant.

Active7 enrollment criteria

Excimer Laser Trabeculostomy Glaucoma Treatment Study

GlaucomaPrimary Open Angle

Evaluation of the safety and effectiveness of the ELIOS System procedure to reduce intraocular pressure (IOP) in adult subjects with mild to moderate primary open-angle glaucoma (POAG) undergoing cataract surgery

Active14 enrollment criteria

A Phase 1b Study of ONL1204 Ophthalmic Solution in Patients With Progressing Open Angle Glaucoma...

Open Angle Glaucoma

The purpose of this study is to demonstrate the safety and tolerability of ONL1204 Ophthalmic Solution in patients with progressing open angle glaucoma. ONL1204 Ophthalmic Solution is a first-in-class inhibitor of fragment apoptosis stimulator (Fas) receptor-mediated cell death that has demonstrated protection of multiple retinal cell types in numerous preclinical models of retinal disease. Apoptosis of retinal ganglion cells is associated with progressive glaucoma. Nonclinical data on ONL1204 Ophthalmic Solution suggest that ONL1204 Ophthalmic Solution may inhibit the cell death pathways in these cells.

Active23 enrollment criteria

Evaluating Home Testing Devices for the Management of Glaucoma

GlaucomaOpen-Angle

With the advancement in technology we have the opportunity of performing the glaucoma testing at home to monitor the disease. The purpose of this study is evaluating the feasibility and patient acceptance of home testing with head mounted perimetry; detection of progression with head mounted perimetry vs office based perimetry; and monitoring the eye pressure measured by patients at home using a portable tonometer.

Recruiting15 enrollment criteria

Clinical Study of Glaukos® Trabecular Micro-Bypass System Model iS3 Infinite Vs. Competitor

GlaucomaGlaucoma1 more

A study of the iStent Infinite product in the treatment of open-angle glaucoma vs competitor

Active2 enrollment criteria

Lamina Cribrosa Depth Change With Change in Eye Pressure

GlaucomaOpen-Angle

This is a study of the compliance of the lamina cribrosa with change in eye pressure.

Recruiting3 enrollment criteria
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