Clinical Study Comparing Two Models of a Travoprost Intraocular Implant
GlaucomaOpen-Angle1 morePhase III study to compare the safety and efficacy of intraocular implants containing Travoprost at two different elution rates versus Timolol Maleate Ophthalmic Solution, 0.5% (Timolol) in reducing elevated intraocular pressure in subjects with open angle glaucoma (OAG) or ocular hypertension (OHT)
Optimal Treatment Protocol for Selective Laser Trabeculoplasty
GlaucomaOpen-Angle2 moreA randomized controlled trial to evaluate which treatment protocol in selective laser trabeculoplasty that is most optimal in terms of efficacy and safety.
Study of a Novel Interposition Supraciliary Implant in Patients With Open Angle Glaucoma (SAFARI...
GlaucomaOpen-AngleThe purpose of this study is to evaluate the safety and effectiveness of implanting 2 novel interposition supraciliary implant as a stand-alone therapy for lowering intraocular pressure (IOP) in patients with primary open angle glaucoma (POAG) who have failed at least one class of topical medical therapy
Safety and Efficacy Study of JV-GL1 in Patients With Open-Angle Glaucoma or Ocular Hypertension...
Ocular HypertensionOpen Angle GlaucomaThe aim of this research study is to assess the safety and feasibility of lowering intraocular pressure (IOP) using an experimental study drug, JV-GL1.
MINIject (MINI SO627) in Patients With Open Angle Glaucoma Using Single Operator Delivery Tool
GlaucomaOpen-Angle Glaucoma EyeThe study will assess safety and performance in patients with open-angle glaucoma uncontrolled by topical hypotensive medications who had previously been implanted with a MINIject glaucoma implant.
Excimer Laser Trabeculostomy Glaucoma Treatment Study
GlaucomaPrimary Open AngleEvaluation of the safety and effectiveness of the ELIOS System procedure to reduce intraocular pressure (IOP) in adult subjects with mild to moderate primary open-angle glaucoma (POAG) undergoing cataract surgery
A Phase 1b Study of ONL1204 Ophthalmic Solution in Patients With Progressing Open Angle Glaucoma...
Open Angle GlaucomaThe purpose of this study is to demonstrate the safety and tolerability of ONL1204 Ophthalmic Solution in patients with progressing open angle glaucoma. ONL1204 Ophthalmic Solution is a first-in-class inhibitor of fragment apoptosis stimulator (Fas) receptor-mediated cell death that has demonstrated protection of multiple retinal cell types in numerous preclinical models of retinal disease. Apoptosis of retinal ganglion cells is associated with progressive glaucoma. Nonclinical data on ONL1204 Ophthalmic Solution suggest that ONL1204 Ophthalmic Solution may inhibit the cell death pathways in these cells.
Evaluating Home Testing Devices for the Management of Glaucoma
GlaucomaOpen-AngleWith the advancement in technology we have the opportunity of performing the glaucoma testing at home to monitor the disease. The purpose of this study is evaluating the feasibility and patient acceptance of home testing with head mounted perimetry; detection of progression with head mounted perimetry vs office based perimetry; and monitoring the eye pressure measured by patients at home using a portable tonometer.
Clinical Study of Glaukos® Trabecular Micro-Bypass System Model iS3 Infinite Vs. Competitor
GlaucomaGlaucoma1 moreA study of the iStent Infinite product in the treatment of open-angle glaucoma vs competitor
Lamina Cribrosa Depth Change With Change in Eye Pressure
GlaucomaOpen-AngleThis is a study of the compliance of the lamina cribrosa with change in eye pressure.