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Active clinical trials for "Osteoarthritis, Knee"

Results 2521-2530 of 2600

Stated-Preferences in Knee Arthroplasty

ArthritisKnee Osteoarthritis1 more

The primary objectives of this study are to apply best-practice stated-preference methods to quantify patient preferences for benefit-risk tradeoffs associated with arthroplasty treatment options for end-stage osteoarthritis of the knee. Duke will develop and administer stated-preference surveys to adult patients (Ages 40-80) with knee pain to collect preference data, estimate the relative importance of treatment features and outcomes, and estimate maximum acceptable risks for given benefits and minimum acceptable benefits for given harms. This study proposal describes plans for the patient stated-preference survey.

Completed3 enrollment criteria

Can 3D Kinematic Parameters Assess the Symptomatic and Functional Severity of KOA?

Osteoarthritis,Knee

There is little study focusing on kinematic parameters in the assessment of the symptomatic and functional severity of knee osteoarthritis (KOA). The purpose of this study is to evaluate the correlations between kinematic parameters and the severity of symptoms and functions in patients with KOA.

Completed18 enrollment criteria

Matched Pair Study - Kinematic vs Mechanical Alignment

OsteoarthritisKnee1 more

The aim of this study is to evaluate postoperative knee function after total knee arthroplasty performed according to the anatomical alignment and compare these results to those of a matched historical cohort of patients operated with mechanical alignment.

Completed8 enrollment criteria

How is Physical Activity Level and Educational Expectations of Patient With Knee Osteoarthritis...

Knee OsteoarthritisPhysical Activity

The primary purpose is to evaluate the level of physical activity in patients with knee osteoarthritis in a spa treatment and doing epidemiological study about this patient.

Completed5 enrollment criteria

Observational Study Investigating the Effectiveness of Fentanyl Matrix in Relieving Pain and Improving...

PainOsteoarthritis3 more

The purpose of this study is to investigate the utility of fentanyl matrix for the treatment of pain due to osteoarthritis (OA) of knee or hip, which was not adequately controlled by non-opioid analgesic (e.g. NSAIDs or COX-II inhibitors) or weak opioids [tramadol HClacetaminophen, tramadol or codeine (or combinations with acetaminophen/ibuprofen)].

Completed11 enrollment criteria

Postural Analysis in Patients With Knee Osteoarthritis

Osteoarthritis

Osteoarthritis is the result of the degeneration of the cartilage to articulate, being currently considered as having an multifactorial cause.The knees are one of the affected joints more due to overload that constitutes the main activator or determinative mechanism for the development of the illness. Beyond pain it has important reduction of the amplitude of movement and the muscular force that causes functional limitation and posture's alterations intervening with the activities of daily life. Therefore, the main objective of this study will be to characterize the posture's alterations and the electromiographic activity in patients with osteoarthritis of knees. For this study 30 citizens will be evaluated, 15 with diagnosis of OA of knees unilaterally and 15 healthful citizens, both the groups will be of the feminine sex with age between 60 to 80 years. The selected patients will answer a questionnaire of personal dates and will have an evaluation fiche, in which will be written down: age, index of corporal mass (IMC), index of Lesquene, index WOMAC (Western Ontario and Mac Master), personal and familiar date of the diagnosis, antecedents, instituted treatments, date of the last x-ray, radiological classification of the osteoarthritis according to Scale of Kellgren, electromiographics date and seeming of the postural evaluation. For the electromiographic evaluation the activity of the muscles vastus lateralis and medial oblique in the isometric contraction maximum volunteer (ICMV) and in the march will be analyzed. And for the postural evaluation will be made three photographs in the sights previous frontal and sagittal right and left, being that, for the analysis of the posturais alterations the program will be used SAPO.

Completed2 enrollment criteria

Chronic Knee Pain Study

Knee Osteoarthritis

Specific Aims: 1) To examine differences between AA and white patients with knee OA in willingness to consider knee joint replacement. 2) To examine the relationship between socio-cultural factors and patient willingness to consider joint replacement. 3) To examine how demographic, socio-cultural, and clinical factors mediate the relationship between race and patient willingness. 4) To examine the relationship between patient willingness and referral to orthopedic care for knee OA (secondary aim). Experimental design/Methodology: A cross-sectional survey study design will be used to examine socio-cultural and clinical factors that may vary by race/ethnicity and may be determinants of willingness to consider joint replacement as a treatment option. Patients with symptomatic and radiographic knee OA from the primary care clinics will be surveyed. Only individuals with knee OA of sufficient severity that would be considered candidates for joint replacement will be included. Analytic strategies include ordinal logistic regression, path analysis, and regression trees. Subject population: The study sample will consist of approximately 133 African American and 419 white patients with OA of the knee in a primary care setting.

Completed5 enrollment criteria

MRI Markers of Cartilage Damage in Knee With Osteoarthritis

OsteoarthritisKnee

The objectives of this study are: to identify and develop techniques to minimize precision errors in magnetic resonance imaging (MRI) evaluation of knee cartilage, and to determine if results from newly-identified MRI techniques in measuring cartilage changes and structure can be reproduced.

Completed9 enrollment criteria

MR Imaging of Knee Osteoarthritis and Acute Knee Injuries

OsteoarthritisKnee

The purpose of this study is to use better magnetic resonance imaging (MRI) techniques to examine the knee and the bony and soft tissue changes so as to better predict the progression of osteoarthritis and acute knee injuries.

Completed9 enrollment criteria

Safety of Electrotherapy in Patients With Knee Osteoarthritis and Cardiac Diseases

Knee Osteoarthritis

This study aimed to asses whether physyical therapy (e.g. electrotherapy in the form of low, medium or high frequency currents, massage and kinetotherapy) for treatment of knee osteoarthritis can induce or aggravate certain cardiac diseases during or immediately after therapy. The physyical treatment described is not a new method, is currently used and recommended in all guidelines for non-pharmacological and non-surgical therapy of knee osteoarthritis. What is not clear is whether application of electrotherapy in the knee area can alter the preexisting cardiac condition.

Completed4 enrollment criteria
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