search

Active clinical trials for "Osteoarthritis, Knee"

Results 1711-1720 of 2600

Efficacy of Radial Shockwave Therapy for Treatment of Pain in Knee Osteoarthritis

Knee Osteoarthritis

The objective of this study is to compare the results of 2000 impulses of radius shockwaves per week with 2000 placebo shockwaves on the treatment of pain and functional incapacity of patients with severe primary knee osteoarthritis, who did not satisfactory respond to previous conventional treatments.

Completed15 enrollment criteria

Shoe Lifts for Leg Length Inequality in Adults With Knee or Hip Symptoms

Leg Length InequalityOsteoarthritis3 more

Limb length inequality is when a person has one leg that is longer than the other. This research will look at correcting limb length inequality in adults with knee or hip symptoms. This study will examine whether ways of measuring leg length inequality in the clinic are valid and reliable, determine whether foot posture (flat foot, normal, and high arch) is related to leg length inequality, and determine whether shoe lifts are a helpful treatment for leg length inequality and knee/hip symptoms.

Completed4 enrollment criteria

A Comparative Study of Knee Systems

Osteoarthritis of the Knee

The custom cutting guides personalized for each patient via pre-operative MRI will result in significantly faster intraoperative time with comparable knee alignment accuracy, cost, knee function, and patient satisfaction.

Completed11 enrollment criteria

Effect of TENS for Pain and Function After Total Knee Replacement

Unilateral Primary Osteoarthritis of KneePrimary Osteoarthritis of Knee Nos

Our primary hypothesis is that TENS decreases pain with movement by reducing hyperalgesia. Minimizing the severe pain experienced during required activities in the immediate postoperative period will promote functional recovery and prevent the development of new chronic pain syndromes.

Completed9 enrollment criteria

Mesenchymal Stem Cells in Knee Cartilage Injuries

Articular Cartilage Disorder of KneeOsteoarthritis1 more

Induction of autologous repair chondrogenesis to regenerate injured articular cartilage using bone marrow mesenchymal stem cells (MSCs) after in vitro expansion under restricted culturing conditions.

Completed8 enrollment criteria

Patient Specific Instrumentation in TKR

Osteoarthritis of the Knee

This is a randomised control trial to assess the benefits of using patient specific instrumentation in total knee replacement surgery. Patient specific instrumentation is an individualised system for total knee replacement surgery. The system has been marketed and is already in use in some centres. The type of implant used remains the same but the sizing of the components, and alignment of the implant is expected to improve. This study assesses any improvement in implant alignment in using the patient specific instrumentation, any improved intra-operative outcomes and any long term clinical outcome improvements for patients.

Completed11 enrollment criteria

Shoe Orthotics for Improvement of Biomechanics and Symptoms of Knee Osteoarthritis

Knee Osteoarthritis

Knee osteoarthritis (OA) is a widespread problem in Canada, leading to decreased quality of life and increased economic burden. Current research has focused on expensive, invasive treatments, whereas inexpensive conservative treatments have received less attention. One such treatment is the use of orthotics to reduce pain and increase function in people with knee OA. Currently, clinical practice guidelines for the use of orthotics are vague and contradictory, and could benefit from more research taking into account foot posture. This study aims to compare the use of two orthotics designs in people with knee OA.

Completed12 enrollment criteria

AposTherapy for Singaporean Patients With Knee Osteoarthritis (OA)

Knee Osteoarthritis

Osteoarthritis (OA) is the most prevalent form of arthritis in the elderly. It is estimated that 7% of men and 11% of women over the age of 65 have KOA. The most significant symptoms of the disease are pain and functional disability. This study has two aims: To characterise the gait patterns and clinical parameters of patients with knee osteoarthritis (KOA) in Singapore at baseline, prior to treatment. To investigate the changes in gait patterns and the clinical benefits of treatment with a new biomechanical device, AposTherapy, for patients with KOA.

Completed15 enrollment criteria

Evaluation of the TruMatch® System in Knee Prosthetic Surgery

OsteoarthritisKnee

Patient specific instrumentation is an alternative to conventional intra- and extra-medullary guides to perform the femoral and tibial cuts in total knee replacement (TKR). This instrumentation could provide a better alignment of a TKR, reduce blood losses and operative time, and improve clinical outcomes. The primary goal of this study is to compare the femorotibial mismatch angle of two groups of patients: patients undergoing posterior stabilized, fixed bearing TKR with conventional Attune® instrumentation (DePuy Johnson & Johnson, Warsaw, Indiana), versus patient undergoing TKR with the TruMatch® (DePuy Johnson & Johnson, Warsaw, Indiana) cutting guide.

Completed14 enrollment criteria

The Use of Fibrin Sealant to Reduce Bleeding After Total Knee Replacement

Total Knee ReplacementPrimary Knee Arthroplasty1 more

A randomized controlled study is performed to address the question of whether the topical application of a novel fibrin sealant, Evicel (Johnson & Johnson Wound Management, Ethicon, Somerville, NJ) in patient undergoing total knee replacement (TKR) reduce the perioperative blood loss and the need for allogenic blood transfusion compared to a control group. We hypothesize that fibrin sealant decrease the drop in post-operative hemoglobin level after total knee replacement.

Completed6 enrollment criteria
1...171172173...260

Need Help? Contact our team!


We'll reach out to this number within 24 hrs