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Active clinical trials for "Osteoarthritis, Knee"

Results 211-220 of 2600

Optimal Anesthetic for Corticosteroid Injections for Knee Osteoarthritis

Knee Osteoarthritis

To evaluate pain relief from corticosteroid injection with and without anesthetic as well as with variable volume of anesthetic. Pain relief will be measured using the VAS pain score at the time of the injection as well as several time points following the injection to capture pain relief longevity. The investigators intend to evaluate how well the patients tolerate corticosteroid mixtures without anesthetic as well as with different volumes of anesthetic. Primary measure will be the time from procedure when postoperative status is considered success (as measured by global perceived improvement score).

Recruiting7 enrollment criteria

Effect Of The Use Of Navigation In The Alignment Obtained When Performing A Total Knee Arthroplasty...

OsteoarthritisKnee2 more

NAOBE is a randomized, open and prospective clinical trial that evaluates the accuracy to achieve an adequate mechanical axis of the lower extremity in obese patients after total knee replacement.

Recruiting14 enrollment criteria

A Phase Ib/II Clinical Trial to Evaluate the Safety and Efficacy of LG00034053 in Patients With...

OsteoarthritisKnee

This study is a multi-center, randomized, placebo-controlled, double-blind clinical study, consisting of Part 1 (Phase 1b) in a sequential, dose-escalating design and Part 2 (Phase 2) in a parallel design.

Recruiting14 enrollment criteria

Investigating the Effect of Interval Walking and Qigong on People With Knee Osteoarthritis: Pilot...

OsteoarthritisKnee

Knee osteoarthritis (KOA) causes pain and limited function that leads to a sedentary lifestyle. The sedentary lifestyle increases the risk of cardiovascular diseases. In addition, many subjects with KOA have knee pain and sleep disturbance that limit their function, quality of life and cause body fatigue. Walking exercise can benefit people with KOA. However, continues walking for more than 30 minutes can increase pain that may stop people from participation in walking exercise. Interval walking may complete the same amount of walking exercise in several separate time periods, without causing extra pain in people with KOA. Mind-body exercise may improve sleep and pain in people with KOA. This study will help researchers to find out whether the interval walking, or mind-body exercise may help people with KOA to improve their pain, fitness level, sleep quality, exercise participation, fatigue, and quality of life. By doing this study, researchers hope to learn more about the interval walking or mind-body exercise in people with KOA.

Recruiting12 enrollment criteria

Impact of a POPOP on Preoperative Health, Eligibility, and Clinical & Patient-Reported Outcomes...

OsteoarthritisKnee4 more

In this pilot study, we will test the hypothesis that a POPOP for currently ineligible UAMS orthopedic surgery patients wanting hip or knee replacement improves markers of preoperative health, ability to reach a BMI threshold <40 kg/m2 required for surgical eligibility, and postoperative outcomes versus SOC.

Recruiting17 enrollment criteria

Knee Osteoarthritis Disabling Pain Program for the Brazilian Unified Health System

OsteoarthritisKnee

This is a Randomized Clinical Trial to compare two interventions for reducing knee pain and improving knee function of patients with knee osteoarthritis. Sixty participants will be randomly allocated to one of the intervention groups, either a knee educational program or a combination of knee educational program and medical interventions. Participants will be assessed primarily on function and pain, as well as other secondary outcomes at baseline, at the end of the interventions, and three months after the end of the interventions.

Recruiting11 enrollment criteria

Physica System Total Knee Replacement Registry Study

OsteoarthritisKnee5 more

The primary objective of this study is to obtain long-term implant survivorship (out to 10 years) and to assess clinical, patient-reported outcome measures, and radiographic data for the commercially available Physica system. For ancillary arm, from baseline to 5-year follow-up.

Recruiting25 enrollment criteria

Bilateral Knee Osteoarthritis: Intra-articular Injection of Filtered Autologous Adipose Tissue Versus...

Bilateral Knee OsteoarthritisAutologous Adipose Tissue

The purpose of the study is to assess the radiological and clinical outcomes comparing two different treatments (Filtered Autologous Adipose Tissue versus Placebo) in patients affecting bilateral knee osteoarthritis. After be randomized, every patient will be treated in both legs, one leg with Adipose Tissue and the other one with Placebo.

Recruiting16 enrollment criteria

Evaluation of Robot-assisted Total Knee Arthroplasty With Automatic Balancing

OsteoarthritisKnee

The goal is to evaluate the outcomes and learning curve of a robot-assisted total knee arthroplasty device with automatic ligament balancing.

Recruiting9 enrollment criteria

External Focus of Attention Posttraumatic Osteoarthritis

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament Rupture2 more

Knee injuries, especially those to the ACL, are common among physically active people. These injuries are frequently treated with surgical reconstruction (ACL reconstruction; ACLR). While ACLR restores stability it does not protect against future injury, long-term pain, disability, and arthritis associated with these injuries. Our study is going to examine new ways to provide feedback about the way people move to determine if these are better at modifying movement patterns that are known risk factors of posttraumatic osteoarthritis development than current standard treatments. If you participate, you will be asked to undergo a movement analysis in a research laboratory while you perform tasks such as walking and hopping. After this initial assessment, you will be randomly allocated to one of 2 treatment groups. Each treatment group will perform 4 weeks (3x/week) of exercises to change the way people walk. Participants will then report for follow-up movement analysis testing 1- and 4-weeks after completing the intervention.

Recruiting5 enrollment criteria
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