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Active clinical trials for "Bone Diseases, Metabolic"

Results 161-170 of 355

AMG 162 in the Treatment of Bone Loss in Subjects Undergoing Aromatase Inhibitor Therapy for Non-metastatic...

Breast CancerLow Bone Mineral Density1 more

The purpose of this trial is to evaluate AMG 162 in the treatment of bone loss in subjects undergoing Aromatase Inhibitor Therapy for Non-metastatic Breast Cancer.

Completed8 enrollment criteria

Zoledronic Acid in the Prevention of Cancer Treatment Related Bone Loss in Postmenopausal Women...

Bone LossBreast Cancer

Post-menopausal breast cancer patients will receive letrozole 2.5 mg daily for the treatment of breast cancer and will be randomized to a treatment group to receive either upfront zoledronic acid 4 mg IV 15-minute infusion every 6 months or delayed start zoledronic acid 4 mg IV 15-minute infusion every 6 months. Delayed start zoledronic acid will be initiated when either the Bone Mineral Density T-score is below -2 Standard Deviations at either the lumbar spine or hip or any clinical fracture unrelated to trauma or an asymptomatic fracture discovered at the month 36 scheduled visit. Letrozole 2.5 mg will be given daily for 5 years.

Completed17 enrollment criteria

Study Evaluating ASTRA TECH Implant System, OsseoSpeed™ Implants in the Upper Jaw in Women With...

Postmenopausal OsteoporosisOsteopenia3 more

The overall objective of the study is to compare treatment with the ASTRA TECH Implant System, OsseoSpeed™ implant in the maxilla of postmenopausal women with and without systemic osteoporosis. The hypothesis is that there will be no difference in marginal bone level alterations between the two groups.

Completed23 enrollment criteria

Effect of Growth Hormone on Bone Metabolism in Anorexia Nervosa

Anorexia NervosaOsteopenia2 more

Decreased bone strength is a serious medical problem present in many women with Anorexia Nervosa, or disordered eating. Women with weaker bones are more likely to suffer broken bones than women with normal bone strength. We are investigating whether a hormone that is naturally produced by the human body, called growth hormone, can help strengthen the bones of women with this type of disordered eating.

Completed6 enrollment criteria

Osteopenia and Renal Osteodystrophy: Evaluation and Management

OsteopeniaRenal Osteodystrophy

The purpose of this study is to demonstrate whether pamidronate will preserve or increase bone mass in patients with adynamic bone disease, caused by low bone turnover.

Completed13 enrollment criteria

Bone Metabolism After Laparoscopic Gastric Bypass Surgery (BABS)

Evaluation of Expected Bone Loss After Bariatric SurgeryPossible Prevention of Bone Loss After Surgery by Calcium and Vitamin D Supplementation

Bariatric surgery leads to rapid weight loss in female and male patients. Less data are available about its impact on bone metabolism. The aim of this study is the investigation of changes in bone mineral density,bone histomorphometric changes, serum bone turnover markers and changes in body fat and muscle composition in patients after laparoscopic gastric bypass surgery.

Completed8 enrollment criteria

A Multi-center Study to Evaluate Bone Loss, Survival Rate and Stability of SPI Implant

Implant Clinical SurvivalDental Implant Bone Loss

The current prospective clinical study's aim is to determine ABT's SPI implant survival rate, crestal interproximal bone resorption during 24 months post implant insertion and to assimilate the drilling sequence during the clinical use of SPI implants.

Completed34 enrollment criteria

Can Risedronate Prevent Periprosthetic Bone Loss After Total Hip Arthroplasty

Bone Loss

Can risedronate given once weekly for 6 months prevent periprosthetic bone loss after uncemented total hip arthroplasty?

Completed8 enrollment criteria

Switch From Tenofovir to Raltegravir for Low Bone Mineral Density

HIVOsteopenia2 more

The purpose of this study is to determine if low bone mineral density (a measurement of how thick and strong bones are) improves in adults with HIV infection who switch their HIV medication tenofovir to another HIV medication raltegravir. Hypothesis:That Bone Mineral Density (BMD) will improve in osteopenic or osteoporotic patients switching from ART including tenofovir disoproxil fumarate (TDF) and a ritonavir-boosted protease inhibitor (r/PI) to ART including RAL+r/PI.

Completed15 enrollment criteria

Denosumab in Metabolic Bone Disease in Chronic Intestinal Failure Patients

Metabolic Bone Disease

Low bone mineral density (BMD) is commonly reported in patients receiving home parenteral nutrition (HPN). Denosumab represent a new drug, which helped to prevent osteoclast. The aim of the study was to assess its value in chronic intestinal failure patients.

Completed4 enrollment criteria
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