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Active clinical trials for "Osteoporosis, Postmenopausal"

Results 191-200 of 295

ValoRization of Dairy Sidestreams to Fight Calcium dEficits iN Postmenopausal Women

OsteoporosisPostmenopausal

The primary objective of this study is to investigate the effects of 12-months supplementation with calcium-enriched permeate, taken alone or in conjunction with inulin, on changes in markers of bone formation and resorption and in bone mass density (BMD) in apparently healthy postmenopausal women compared with calcium-carbonate or maltodextrin supplementation.

Completed17 enrollment criteria

Soluble Corn Fiber Effect on Bone Resorption in Post Menopausal Women

OsteoporosisPostmenopausal

This study is designed to study the dose response effect of continuous Soluble Corn Fiber (SCF) intake over a 50 day period on bone resorption in healthy post menopausal women using the 41Calcium methodology. To further understand the dose response effect of SCF bone biomarkers will be studied. Our hypothesis is that soluble corn fiber will reduce bone resorption in a dose dependent manner in comparison to placebo when estimated by urinary 41Calcium excretion as well as bone biomarkers of resorption.

Completed2 enrollment criteria

Study to Evaluate AMG 162 in the Prevention of Postmenopausal Osteoporosis

Postmenopausal Osteoporosis

This study will determine whether treatment with AMG 162 can prevent lumbar spine bone loss in both early and late postmenopausal women with osteopenia, and to further test the safety and tolerability of AMG 162 in this population.

Completed2 enrollment criteria

Prevention of Osteoporosis: Effects of Mini-trampoline Training on the Bone Remodeling

Perimenopausal Bone LossPostmenopausal Osteopenia

The aim of the project is to study the effects on bone remodeling induced by training carried out with the trampoline in order to evaluate the reduction of the resorption itself and therefore the onset of osteoporosis in women.

Completed10 enrollment criteria

Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis and CVD Risk

Postmenopausal OsteoporosisGut Microbiota1 more

Aim to evaluate the effects of blackcurrant supplementation on changes in gut microbiome, bone mass, and CVD risk factors in adult women.

Completed22 enrollment criteria

Prevention of Osteoporosis in Breast Cancer Survivors

Postmenopausal Osteoporosis

The purpose of this study is to test whether strength/weight training exercises enhance the effectiveness of calcium, vitamin D, and risedronate for the prevention and treatment of osteoporosis in postmenopausal breast cancer survivors.

Completed18 enrollment criteria

Risedronate In The Prevention Of Osteoporosis In Osteopenic Postmenopausal Women

OsteoporosisPostmenopausal

To confirm the superiority of 5 mg daily risedronate as compared to placebo in maintaining or increasing bone mass in lumbar spine in osteopenic postmenopausal women To confirm the efficacy of 5 mg daily risedronate in osteopenic postmenopausal women in maintaining or increasing bone mass in proximal femur and decreasing bone resorption To confirm general safety of 5 mg daily risedronate as compared to placebo

Completed6 enrollment criteria

Effects of Arzoxifene on Bone Mass and the Uterus

Postmenopausal Bone Loss

The purposes of this study are to determine: The effects of arzoxifene on bone mineral density (bone mass) at the spine and hip in postmenopausal women. The effects of arzoxifene on the uterus (womb) in postmenopausal women. The effects of arzoxifene on blood tests that measure changes in bone rebuilding in postmenopausal women with low bone density. The effects of arzoxifene on blood lipids (fats) and other blood markers of heart disease risk. The safety of arzoxifene and any side effects that might be associated with its use.

Completed8 enrollment criteria

Vitamin K Supplementation in Post-Menopausal Osteopenia

Post-Menopausal OsteoporosisPost-Menopausal Osteopenia

The purpose of this study is to determine whether supplementation with 5 mg vitamin K daily over a 2-year period will prevent bone loss in post-menopausal women with osteopenia.

Completed12 enrollment criteria

Tart Cherry Supplementation and Women's Bone Health Study

OsteoporosisPostmenopausal2 more

In spite of aggressive approaches to prevent and treat osteoporosis, it remains one of the most costly and debilitating diseases associated with aging. The pursuit of alternative approaches for preventing bone loss has included the investigation of a number of promising plant-based foods that can be incorporated into the diet. This project is an extension of our pre-clinical studies with tart cherry, designed to determine whether the findings from our animal study can be extended to humans. Thus, the purpose of this project is to investigate the dose-dependent effect of tart cherry juice consumption on biomarkers of bone metabolism in women, aged 65-80 years. The hypothesis to be tested is that three months of tart cherry supplementation will improve bone biomarkers in a dose-dependent manner. Moreover, these improvements in bone metabolism will correspond to a decrease in markers of inflammation and oxidative stress.

Completed16 enrollment criteria
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