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Active clinical trials for "Osteoporosis"

Results 931-940 of 1458

Does Omeprazole Decrease Intestinal Calcium Absorption?

OsteoporosisAchlorhydria2 more

The purpose of this study is to measure the effect of omeprazole on intestinal calcium absorption in postmenopausal women.

Completed8 enrollment criteria

Education for Osteoporosis in Persons With Existing Fractures

Osteoporosis

We wish to investigate whether a weekly, 2½ hour group-based osteoporosis education intervention (the Osteoporosis Prevention and Self-Management Course), is different to one session course (1x 2½ hours) on osteoporosis knowledge, confidence to eat calcium-containing foods, confidence to exercise, and amount of exercise undertaken after three and nine months of follow-up in people aged over 50 years who have already had a bone fracture.

Completed10 enrollment criteria

Strength Training for Older Breast Cancer Survivors

Breast NeoplasmOsteoporosis1 more

Women aged 50 and older are disproportionately affected by breast cancer, not only in terms of new diagnoses, but also in terms of survivorship. Approximately 85% of women who receive a first diagnosis of breast cancer are aged 50 and over, thus older women constitute the largest group of breast cancer survivors. Yet, few studies have focused on evaluating whether physical activity and exercise interventions affect long-term symptoms, physical fitness and function, and body composition of older breast cancer survivors. Due to the combined effects of breast cancer, related treatments and aging it is likely that exercise is even more beneficial for older breast cancer survivors than for younger survivors. Along with the cancer-related symptom of fatigue common to cancer survivors, older survivors face age-related declines in bone and muscle mass, muscle strength, bone health and physical function (gait and balance) that are likely exacerbated by reduced physical activity in survivorship and side effects of adjuvant cancer treatment. All women, regardless of age, are at risk for breast cancer recurrence. Recent epidemiologic evidence suggests a link between exercise and reduced risk of cancer recurrence in breast cancer survivors. Strength training is specifically suited to reverse or slow age-related declines in bone, muscle, strength and function and has shown promise to reduce cancer-related fatigue. However, no controlled trials of strength training in older breast cancer survivors have been conducted.

Completed7 enrollment criteria

The Effect of a Short Educational Program on Young Women's Knowledge and Beliefs About Osteoporosis...

Osteoporosis

The purpose of the study is to determine the effect of a short educational program on young women's knowledge and beliefs about osteoporosis. They hypothesis is that following the intervention women who receive the educational program will have greater knowledge and beliefs about osteoporosis.

Completed2 enrollment criteria

A High-resolution Peripheral Quantitative Computed Tomography Study in Postmenopausal Women Previously...

Low Bone MassLow Bone Mineral Density2 more

To evaluate the combined effect of denosumab treatment and discontinuation on cortical thickness at the distal radius by High Resolution-Peripheral Quantitative Computed Tomography (HR-pQCT). Participants randomized to either denosumab or placebo in the 20050179 (NCT00293813) study who completed that study (ie, attended an end of study visit) can be included in this study. At least 12 months should have elapsed since the patient's 20050179 end of study visit.

Completed18 enrollment criteria

Wiser Choices in Osteoporosis Choice II: A Decision Aid for Patients and Clinicians

OsteoporosisOsteopenia1 more

Emphasis in treating osteoporosis has been on T-scores rather than overall fracture risk. Fracture Risk Assessment Tool (FRAX) supports a risk sensitive approach to osteoporosis treatment by providing an absolute fracture risk. FRAX combined with a decision aid may promote a shared decision making approach with patients, allowing the clinician and patient to weigh potential fracture risk (without treatment), versus risk reduction with medication (including side effects and costs). OSTEOPOROSIS CHOICE II will test the effectiveness of: FRAX FRAX + decision aid Usual care (no decision aid and no FRAX given to clinician)

Completed5 enrollment criteria

Zoledronate in Preventing Osteoporosis in Patients With Primary Malignant Glioma

Brain TumorsOsteoporosis1 more

RATIONALE: Zoledronate may prevent bone loss in patients with primary malignant glioma. PURPOSE: This phase II trial is studying how well zoledronate works in preventing osteoporosis in patients with primary malignant glioma.

Completed22 enrollment criteria

Study Evaluating Bazedoxifene Dose-Response in Japanese Patients With Postmenopausal Osteoporosis....

Postmenopausal Osteoporosis

Dose-response in Japanese patients with postmenopausal osteoporosis.

Completed2 enrollment criteria

FREE Study - Fracture Reduction Evaluation

OsteopeniaOsteoporosis2 more

The primary objective of this study is to compare the effectiveness of standard medical therapy alone to kyphoplasty using the KyphX system for the treatment of acute vertebral body compression fractures.

Completed25 enrollment criteria

Effect of Exercise Training and Soy-based Nutritional Supplementation on Prevention of Osteoporosis...

OsteoporosisOsteopenia

The purpose of the study is to determine the effectiveness of combining exercise training (i.e. weight lifting and walking) and dietary supplementation with a soy-based nutritional supplement for increasing bone mineral density. We hypothesize that the exercise training and soy-based supplement will be additive for increasing bone mineral density.

Completed17 enrollment criteria
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