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Active clinical trials for "Pancreatic Neoplasms"

Results 2471-2480 of 2501

Portal Vein Resection in Pancreatic Neuroendocrine Tumours

Pancreas NeoplasmNeuroendocrine Tumors

The limited evidence on the value of portal vein resection in patients with borderline resectable and/or locally advanced PanNENs is an incentive to carry out a retrospective multicentre study amongst centres with specific interest in the management of PanNENs and with experience on vascular reconstruction. Unlike previous studies on pancreatic cancer, it is more difficult to standardise the comparative parameters as the definition of borderline resectable disease has never been published for PanNENs. Similarly, different histological classifications make impossible to collect data exclusively on T3 tumours. Therefore, we aim to compare the short and long-term outcomes (including the impact of the histological depth of vascular invasion on survival) between patients undergoing standard PD and PD with portal vein resection for PanNENs, (regardless of T stage), by collecting and analysing retrospective data in this single centre study

Unknown status5 enrollment criteria

Proteomic Analysis of HLA Complex in Solid Cancers: Breast, Ovary, Colon, Rectum, Stomach, and Pancreas...

Colorectal NeoplasmsStomach Neoplasms3 more

The purpose of this study is to evaluate the presence of proteins in solid tumors which may lead to an immune response

Unknown status3 enrollment criteria

Biomarkers of Pancreatic Cancer and New Way to Detection

Pancreatic Cancer

Amphoteric regulatory protein (AREG), a member of epidermal growth factor (EGF) family, is expressed in many tumors.Our study confirmed that the expression of AREG in the serum of patients with pancreatic cancer is significantly higher than that of patients with benign pancreatic diseases and healthy people, which is expected to become a new early serum marker of pancreatic cancer. The serum concentration of AREG was detected by traditional ELISA and compared with CA-199, which was a conventional tumor marker of pancreatic cancer. Next, we compare the advantages of using sensor to detect AREG compared with ELISA.

Unknown status8 enrollment criteria

The Italian Version of Cancer Worry Scale

Cancer FearPancreatic Cancer

An Italian language version of the Cancer Worry Scale is not available yet. The aim of this study is to develop and validate the Italian version of Cancer Worry Scale through subjects at high risk of pancreatic cancer for familiarity/genetic predisposition, or suffering from premalignant cystic lesions.

Unknown status12 enrollment criteria

Biodegradable Pancreatic Stents for the Prevention of Postoperative Pancreatic Fistula After Cephalic...

Pancreatic FistulaPancreas Neoplasm3 more

Background: postoperative pancreatic fistula (POPF) remains the most important morbidity after pancreaticoduodenectomy (PD). There is no consensual technique for pancreatic reconstruction and many surgeons use a transanastomotic drain. Currently, the stents used are not degradable and they can cause obstruction, stricture and pancreatitis. The use of biodegradable stents that disappear a few months after the intervention could have a role in the prevention of pancreaticojejunostomy complications. Material and method: A single-center prospective randomized study was planned with patients undergoing PD. A duct-to-mucosa end-to-side anastomosis is performed for the pancreaticojejunal anastomosis and the stent is placed from the pancreatic duct to the jejunum. The primary outcome of the study is the evaluation of the presence of POPF (drainage fluid amylase value of > 5000 U/L on the first day).

Unknown status2 enrollment criteria

Magnetic Compressive Technique for Pancreatic Intestinal Anastomosis

Pancreatic NeoplasmsPancreatitis1 more

In recent five years, the investigators have successfully developed different types of magnets and utilized in biliojejunostomy, concomitant biliojejunostomy and pancreaticojejunostomy during Whipple. This study is designed as a prospective study by utilization of the bar-like magnets for pancreaticojejunostomy.

Unknown status7 enrollment criteria

Radiotherapy Assessments During Intervention ANd Treatment (RADIANT)

Radiation TherapyCancer17 more

Collect blood samples and associated clinical data prior to, during, and post radiation treatment.

Unknown status7 enrollment criteria

Coordinating and Data Management Center for the Consortium for the Study of Chronic Pancreatitis,...

Chronic PancreatitisDiabetes1 more

The data management systems, auditing, and monitoring effort are supported by the MD Anderson Cancer Center Clinical Research Support Center (CRSC). The The Coordination and Data Management Center (CDMC) will provide high quality, efficient and consistent leadership and services in all aspects of data quality and assurance; data harmonization and management; while providing assistance to the projects in disseminating and interpreting those data. The CDMC PI will provide statistical (study design, analysis plans, data analysis, and interpretation), data management, and data monitoring/auditing (data quality assurance and harmonization) expertise for the proposed projects. The Cancer Center will have access to identifiable data from studies; analysis of this data will not be conducted under this protocol. Any future analysis conducted on data or specimens as part of CPDPC protocols will be conducted under a separate IRB approved data or lab protocol. The CDMC will leverage existing support, infrastructure, and resources from the Data Management and Coordinating Center for the Global Cancer Early Detection and the clinical expertise of the Division of Pathology/Lab Medicine at MDACC.

Unknown status2 enrollment criteria

Circulating Cell-free Tumor DNA(ctDNA) in Pancreatic Cancer

Pancreatic Cancer

The aim of the study is to evaluate whether peripheral circulating cell-free tumor DNA(ctDNA) can help early screening of pancreatic cancer recurrence or not. And we are also planning to evaluate correlation between ctDNA with clinical outcome of pancreatic cancer.

Unknown status5 enrollment criteria

Systematic Lymph Node Sampling and Analysis in Patients With Pancreatic Cancer

Pancreatic Cancer

Prospective investigation of the ratio between malignant and total number of lymph nodes in predefined lymph node stations in patients resected for pancreatic adenocarcinoma. A national Danish project.

Unknown status2 enrollment criteria
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