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Active clinical trials for "Pars Planitis"

Results 21-30 of 31

A Study of the Safety and Efficacy of a New Treatment for Non-Infectious Intermediate or Posterior...

Intermediate UveitisPosterior Uveitis

This study will evaluate the safety and efficacy of an intravitreal implant of dexamethasone for the treatment of non-infectious intermediate or posterior uveitis.

Completed3 enrollment criteria

Suprachoroidal Injection of CLS-TA in Patients With Non-infectious Uveitis

UveitisUveitis6 more

This open-label study is designed to evaluate the safety of suprachoroidally administered triamcinolone acetone injectable suspension, CLS-TA, in patients with non-infectious uveitis with and without macular edema.

Completed6 enrollment criteria

Safety Study of Suprachoroidal Triamcinolone Acetonide Via Microneedle to Treat Uveitis

UveitisIntermediate Uveitis3 more

This study is designed to determine the safety and tolerability of a single microinjection of triamcinolone acetonide (TRIESENCE®) into the suprachoroidal space (SCS) of patients who have non-infectious uveitis.

Completed9 enrollment criteria

Myfortic for the Treatment of Non-infectious Intermediate Uveitis

UveitisIntermediate

The objective of this clinical trial is to evaluate the efficacy, safety and tolerability of enteric-coated mycophenolate sodium (Myfortic®) in combination with low-dose corticosteroids (Decortin H®) compared to a monotherapy with low-dose corticosteroids (Decortin H®) in subjects with chronic intraocular inflammation (non-infectious intermediate uveitis).

Completed40 enrollment criteria

Safety &Efficacy of CF101 to Subjects With Uveitis

UveitisPosterior2 more

This is a Phase 2, randomized, double-masked, placebo-controlled study subjects with active, sight-threatening, noninfectious intermediate or posterior uveitis.

Withdrawn34 enrollment criteria

Intravitreal Sirolimus as Therapeutic Approach to Uveitis

UveitisIntermediate Uveitis2 more

The purpose of this study is to find out about the safety and effectiveness of two different doses the study drug, sirolimus, administered intravitreally in patients with uveitis. The potential effectiveness of sirolimus can be utilized to control inflammation in uveitis and yet avoid the potential complications that are usually associated with the systemic use of the drug and other immunomodulatory therapies. In this study, the investigators will administer sirolimus inside the eye (intravitreally) in one of two doses (440mcg/mcL or 880mcg/mcL). Local administration of sirolimus to the eye is not expected to have effects on the rest of the body. Therefore, it may offer a safer way than the current methods used to control the inflammation caused by non-infectious uveitis.

Unknown status35 enrollment criteria

Study of the Safety, Tolerability, and Bioactivity of Tocilizumab On Patients With Non-infectious...

Intermediate UveitisPosterior Uveitis1 more

In the STOP-UVEITIS study, we propose to evaluate the safety, tolerability, and bioactivity of two doses of Tocilizumab (4mg/kg and 8mg/kg), administered monthly, in patients with non-infectious intermediate, posterior, or panuveitis.

Unknown status65 enrollment criteria

MAGNOLIA: Extension Study of Patients With Non-infectious Uveitis Who Participated in CLS1001-301...

UveitisUveitis6 more

This study is a non-interventional, observational extension of the Parent study, CLS1001-301 (NCT02595398). The purpose of this study is to characterize the continued clinical benefit(s) regarding safety and efficacy of suprachoroidally administered CLS-TA, triamcinolone acetonide injectable suspension, for the treatment of macular edema associated with non-infectious uveitis.

Completed4 enrollment criteria

Variations in Retinal Nerve Fiber Layer Thickness During Uncomplicated Anterior and Intermediate...

Anterior UveitisIntermediate Uveitis

This study investigates the variations in the retinal nerve fiber layer (RNFL) thickness during uncomplicated anterior and intermediate uveitis, respectively. The objectives are to 1 ) confirm the RNFL thickening during an uncomplicated anterior uveitis as described in the literature, 2) measure the RNFL thickness during an uncomplicated intermediate uveitis specifically and 3) describe the variation in time of RNFL thickness during the two types of uveitis.

Completed9 enrollment criteria

Quality of Life in Patients With Intermediate Uveitis

Macular Edema

The aim of this study is to determine if macular edema is associated with less visual function and quality of live in patients with intermediate uveitis

Completed3 enrollment criteria

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