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Active clinical trials for "Seizures"

Results 481-490 of 775

To Evaluate the Long-Term Safety and Efficacy of Pregabalin in Patients With Partial Seizures

Seizure DisorderPartial

To evaluate the long-term safety and efficacy of pregabalin in patients with partial seizures.

Completed3 enrollment criteria

Reducing Seizure Frequency Using Cooling of the Head and Neck

EpilepsySeizures

Doctors use cooling of the brain to help stop seizures. This procedure is usually accomplished through surgery. Cooling of the face and scalp may also cool the brain, avoiding the need for surgery. The purpose of this study is to assess a head-neck cooling device that the patient can wear. Researchers will determine whether the device can change the frequency of seizures in people with epilepsy. Study participants must be 21 years of age or older and must experience seizures that occur once a week on a regular basis. Participants will be asked to keep a detailed seizure diary for a 12-week period before the date of the first cooling session. For each of the four cooling sessions, participants will be admitted to the hospital overnight. They will undergo a physical and neurological exam and an EEG (electroencephalogram). They will also swallow a temperature-sensor pill. Participants will have one 60-minute cooling session once a week for 4 weeks. Investigators will paste temperature-sensing electrodes on the scalp, forearm, abdomen, and leg. Participants will then be fitted with the cooling unit and the session will begin.

Completed13 enrollment criteria

Childhood Absence Epilepsy Rx PK-PD-Pharmacogenetics Study

Childhood Absence EpilepsyPetit Mal Epilepsy2 more

The purpose of this study is to determine the best initial treatment for childhood absence epilepsy.

Completed24 enrollment criteria

An Evaluation Of The Fitting Success Rate Of Senofilcon A Soft Contact Lenses In Three Designs....

Myopia

This study will compare the on-eye fitting characteristics of three types of contact lenses. Each lens pair will be worn for 30 to 45 minutes before assessment and the results will be compared to mathematically calculated fitting characteristics.

Completed13 enrollment criteria

The Impact of Electroencephalographic (EEG) Seizure Treatment in Neonatal Encephalopathy

SeizuresEncephalopathy

This is a prospective, randomized, single-center pilot trial of term and near term (≥ 36 weeks gestation) infants with encephalopathy or seizures comparing a "EEG Seizure Treatment Group" or ESG with a "Clinical Seizure Treatment Group" or CSG. The investigators hypothesize that the accurate detection and treatment of EEG seizures will decrease the seizure burden and improve outcomes in newborn infants with seizures and/or hypoxic-ischemic encephalopathy (HIE).

Completed17 enrollment criteria

Bioequivalency Study of Levetiracetam 1g Tablets Under Fed Conditions

Seizures

The objective of this study was to prove the bioequivalence of Levetiracetam 1000 mg Tablets under fed conditions

Completed2 enrollment criteria

Bioequivalency Study of 600 mg Oxcarbazepine Tablets Under Fasting Conditions

SeizuresEpilepsy

The objective of this study was to assess the bioequivalence of a potential generic 600 mg oxcarbazepine tablet formulation compared with Novartis Pharmaceutical's 600 mg oxcarbazepine tablet, Trileptal, following a single 600 mg dose administered under fasting conditions.

Completed4 enrollment criteria

To Demonstrate the Relative Bioavailability of Sandoz Inc. and UCB Pharma, Inc (Keppra) 750 mg Levetiracetam...

Seizure

To demonstrate the relative bioavailability of Sandoz Inc. and UCB Pharma, Inc (Keppra) 750 mg Levetiracetam tablets in healthy adult volunteers under fasting conditions.

Completed3 enrollment criteria

Vision Testing in Patients With Partial Seizures Receiving Either Lyrica or Placebo

EpilepsiesPartial

Patients with partial seizures currently taking 1-3 antiepileptic medications will have a 50:50 chance to receive Lyrica 300 mg per day or placebo (no active ingredients) added on to their current medications for 3 months. Neither the study doctor nor the patient will know the medication assignment. Vision testing will be performed prior to receiving the study treatment and at the end of the study to see if there are any changes.

Completed4 enrollment criteria

Clinical Evaluation of Fitting Investigational Contact Lenses Phase 2

Visual Acuity

This study is a single arm, non-randomized, open label, bilateral, non- dispensing clinical trial with only one visit. The Eye Care Providers will be provided with a fitting guide and will determine the initial study lens selection. Each subject will wear either the investigational contact lenses or marketed contact lenses for approximately 30-90 minutes. This study aims to evaluate the ECPs impression of the fitting guide for a novel multifocal lens and also their success in fitting the lenses.

Completed25 enrollment criteria
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