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Active clinical trials for "Gambling"

Results 51-60 of 117

Investigation of Naltrexone for Pathological Gambling

Pathological Gambling

The investigators plan to investigate the safety, tolerability, and efficacy of the opioid antagonist naltrexone in Pathological Gambling. We hypothesize that naltrexone will be superior to placebo in reducing gambling urges and behavior, when combined with adjuvant non-pharmacological treatment as usual.

Completed21 enrollment criteria

Development and Validation of a Mindfulness Intervention for Problem Gambling: An Exploratory Study...

Gambling

In recent years, mindfulness meditation has been shown to be a promising approach for alleviating emotional distress associated with chronic medical and psychiatric conditions and in reducing relapse following treatment for depression. The applicability of mindfulness meditation to problem gambling has not yet been explored. Mindfulness meditation may be particularly suitable for this clinical disorder as it stresses a process-oriented, metacognitive, approach to cognitive pathology in contrast to a content-focused approach, characteristic of traditional approaches to treating cognitive psychopathology. Gambling-related cognitive psychopathology is a well-known characteristic of problem gambling and frequently the target of therapy. Although there is growing evidence that cognitive-behavioral treatments are effective for gambling, outcomes may be improved by teaching gamblers additional ways to cope with cognitive distortions that emphasize metacognitive processes.

Completed4 enrollment criteria

Nalmefene Gambling Study: Study of Nalmefene HCl in the Treatment of Pathological Gambling

Pathological Gambling

The purpose of this study is to determine if nalmefene is safe and effective in the treatment of pathological gambling.

Completed1 enrollment criteria

Cognitive Behavioral Therapy for Treatment of Pathological Gambling

Gambling

This study will determine the effectiveness and cost-effectiveness of three different treatment strategies in reducing gambling behaviors.

Completed4 enrollment criteria

Emotion Regulation Group Treatment for Gambling Disorder - a Pilot Trial

Gambling Disorder

Group cognitive behavioral therapy for Gambling Disorder (GD) with a focus on emotion regulation - A pilot study This pilot study will evaluate the feasibility and possible effectiveness of a novel treatment protocol developed within the research group including emotion regulation techniques for the treatment of GD.

Completed4 enrollment criteria

Computer-based Self-Help Program for People With Gambling Problems

GamblingPathologic

The study examines the effectiveness of a computer-based self-help-program for individuals with problematic or pathological gambling behavior.The main objective of the study is to investigate the extent to which the online program leads to a significant reduction in pathological gambling (primary outcome), depression and gambling-specific dysfunctional thoughts. The program is expected to lead to a significant reduction regarding all measures when compared to a control group. The study is conducted as a randomized-controlled trial with one intervention group and one wait-list control group.

Completed9 enrollment criteria

Physical Activity Pathological Gamblers

Gambling Disorder

Gambling Disorder (GD) is defined as the recurrent and persistent act of betting which leads to clinical impairments,. The latest edition of the Diagnostic and Statistical Manual of Mental Disorders (5th edition) conceptualizes GD as a behavioral addiction due to the similarities between GD and substance addictions in clinical presentation, association with personality factors, genetic transmission and treatment options. Previous studies found potential benefits of physical activity in treatment of addictions in general and GD in particular, such as reducing desire to play, betting and depressive and anxious symptoms.

Completed9 enrollment criteria

Online Coping Skills Counseling for Problem Gambling and Trauma

Gambling DisorderTrauma3 more

This randomized controlled trial examines the efficacy of two behavioral therapies. Seeking Safety, which addresses co-occurring problem gambling (PG) and posttraumatic stress disorder (PTSD), is being compared to Cognitive-Behavioral Therapy for PG, which addresses only PG. Both models are delivered via telehealth.

Completed7 enrollment criteria

Treatment of Gambling Disorder With Fast Acting Opiate Antagonist, Naloxone Nasal Spray

GamblingOpioid2 more

Non-controlled pilot study. Two groups: Group A: naloxone nasal spray max 8 mg/per day; Group B: naloxone max 16 mg/per day. Study duration 8 weeks. Brief intervention.

Completed10 enrollment criteria

Milk Thistle in Pathological Gambling

Pathological GamblingGambling Disorder

The goal of the proposed study is to evaluate the efficacy and safety of silymarin in individuals with gambling disorder. The hypothesis to be tested is that silymarin will be more effective and well tolerated in subjects with gambling disorder compared to placebo. The proposed study will provide needed data on the treatment of a disabling disorder that currently lacks a clearly effective treatment.

Completed15 enrollment criteria
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