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Active clinical trials for "Pemphigoid, Bullous"

Results 51-60 of 67

Role of Proteasomes in a Dermatological Autoimmune Disease: Bullous Pemphigoid

PemphigoidBullous3 more

The primary objective of this study is to describe and compare plasmatic anti-proteasome auto-antibody concentrations among three distinct groups: (1) patients suffering from bullous pemphigoide; (2) patients suffering from other dermatological auto-immune diseases; (3) an elderly control group.

Terminated29 enrollment criteria

Pruritus and Pemphigoid in Nursing Home Patients

PemphigoidPruritus

The primary objective of this observational study is to describe the prevalence of pruritus and pemphigoid in nursing home patients. Secondary outcomes are the relationships of demographic factors and medical risk factors with pemphigoid, including dementia and neuropsychiatric symptoms, medication use and Karnofsky score.

Completed7 enrollment criteria

Clinical Characteristics of Pruritus and Evaluation of Quality of Life in Patients With Bullous...

Bullous Pemphigoid

Whereas pruritus is a major symptom in bullous pemphigoid, its characteristics and its impact on quality of life have been little studied. The objective of this study is to learn more about pruritus characteristics of patients with bullous pemphigoid, and in consequence to better understand the pathophysiology of pruritus, and then to better treat pruritus in this condition.

Completed7 enrollment criteria

Compassionate Use of Dupilumab for Adult Patients With Bullous Pemphigoid

Bullous Pemphigoid

The objective of the program is to provide patients with Bullous Pemphigoid (BP), that participated in the R668-BP-1902 (NCT04206553) phase 2/3 study, dupilumab treatment and evaluate the long-term safety of dupilumab.

Available10 enrollment criteria

Clinical Trial on the Effect of Autologous Oral Mucosal Epithelial Sheet Transplantation

Limbal Stem Cell DeficiencyStevens-johnson Syndrome2 more

To investigate the effect of ocular surface reconstruction and assess the safety in cultivated oral mucosal epithelial cell sheet transplantation (COMET) regarding patients with cicatricial change of ocular surface.

Available12 enrollment criteria

Interest of Dosage of Anti-PB230, Anti-PB180 and Cytokines for Monitoring of Patients Suffering...

Bullous Pemphigoid

Bullous pemphigoid is the most common subepidermal autoimmune blistering disease of the skin in European countries, including France. Immunologically, BP is characterized by the production of autoantibodies directed against two major components of the hemidesmosome, BP180 and BP230. The anti-BP180 autoantibody is detected in 79-93% of cases of bullous pemphigoid and its serum level at diagnosis have been correlated with disease activity. The anti-BP230 autoantibody is detected in 57%-63% of bullous pemphigoid cases and its score at diagnosis did not correlate with disease activity. Up to now, no clinical or immunologic factors have been identified to predict outcome of patients with good or poor prognosis bullous pemphigoid as defined by long complete remission off therapy and recurrent disease requiring maintenance therapy for years. The usefulness of BP180 or BP230 ELISA scores for monitoring BP patients during treatment also remains unclear.

Completed4 enrollment criteria

Impact of Neurological Diseases on the Prognosis of Bullous Pemphigoid: A Retrospective Study of...

Bullous Pemphigoid

Bullous pemphigoid affects mainly elderly patients. It is often associated with neurologic disorders, which represent a major risk factor of the disease

Completed2 enrollment criteria

Comparison of Two Therapeutic Strategies of Dermoval in Treatment of Bullous Pemphigus

Bullous Pemphigoid

to compare efficacity and tolerance of two stratégies of dermoval application in treatment of bullous pemphigus.

Completed9 enrollment criteria

Telederm and Bullous Pemphigoid

Bullous Pemphigoid

The purpose of the study is to improve the quality of future clinical trials in bullous pemphigoid (BP), the investigators will monitor repeated measurement data from patients with BP on standard-of-care treatments at four week intervals for four months.

Completed4 enrollment criteria

Observational Study Assessing Outcomes, Treatment Patterns and Related Costs in Patients in Bullous...

Bullous Pemphigoid

The study is an observational, multi-center, prospective, non-interventional and open-label data collection study assessing outcomes, treatment patterns, adverse events and costs in patients diagnosed with bullous pemphigoid. The patient enrollment period will be 1 year with a follow-up (observation period) of 1 year for each patient. Four dermatology centres in France will participate. The hypothesis to be answered by the study is that superpotent topical corticosteroid therapy is properly used to treat bullous pemphigoid in real-world life as recommended by French guidelines and whether this treatment influences the medical costs by comparison with systemic therapies (e.g. methotrexate or prednisone).

Unknown status6 enrollment criteria
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