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Active clinical trials for "Peptic Ulcer Perforation"

Results 1-10 of 16

Impact of Abdominal Drains on the ERAS Pathway in Peptic Perforation

Perforated Peptic UlcerFast Track Surgery3 more

This study plans to assess the effect of placement of abdominal drains on the outcomes of ERAS (Enhanced recovery after surgery) protocol in the perioperative management of peptic perforation. In the study arm ERAS protocol will be implemented avoiding use of abdominal drain. In the control arm abdominal drains will be placed in the early post operative period while using the ERAS protocol. The effect of drains on duration of post operative stay and other return to physiological parameter like onset of ambulation, oral intake, passing flatus and feces etc. will be studied. The investigators hypothesize that the non-placement of abdominal drain postoperatively will not have worse outcomes than in cases where it is used postoperatively, in terms of length of hospital stay. .

Recruiting13 enrollment criteria

Early Oral Feeding Versus Traditional Delayed Oral Feeding Post-perforated Peptic Ulcer Repair

Peptic Ulcer Perforation

This study aims to evaluate safety and benefits of early oral feeding compared to traditional delayed oral feeding in patients undergoing perforated peptic ulcer repairs. Study population & Sample size :(

Recruiting8 enrollment criteria

Omitting Drains After Repair of Peptic Ulcer Perforations

Peptic Ulcer Perforations

. This study aimed to evaluate ERAS application outcomes via omitting the intraabdominal drains compared to regular using of the drains in patients undergoing perforated duodenal ulcer repairs in emergency abdominal surgeries.

Recruiting7 enrollment criteria

Falciformopexy for Treatment Perforated Peptic Ulcer.

Perforated Peptic Ulcer

Use the falciform ligament flap for the treatment of perforated peptic ulcer

Not yet recruiting4 enrollment criteria

Laparoscopic Versus Open Repair of Peptic Ulcer Perforation

SurgeryEmergencies1 more

Although laparoscopic repair (LR) of perforated peptic ulcers (PPUs) has long been accepted, clinical evidence comparing LR versus open repair (OR) remains lacking. The aim of this study is to evaluate the feasibility, safety and outcome of laparoscopic gastric repair and compare it with the outcome open repair by relying on a propensity score matching statistical technique

Recruiting6 enrollment criteria

Open vs Laparoscopic Repair of Perforated Peptic Ulcer

Perforated Peptic Ulcer

comparison between outcomes of both open and laparoscopic repair of perforated peptic ulcer

Not yet recruiting7 enrollment criteria

Combined Endoscopic & Radiologic Intervention For Management Of Acute Perforated Peptic Ulcer

AbdomenAcute

The investigators included all patients who were developed acute perforated peptic ulcer manifestations and were admitted to our hospital between December 2019 to August 2021. The study was approved by the research and Ethics committee of our university and performed in accordance with the code of ethics of the world medical association (Declaration of Helsinki) for studies involving humans. A written informed consent was obtained from all participants. The sample size was calculated using open Epi program using the following data ; confidence interval 95% , power of test 80% , ratio of unexposed/exposed 1, percent of patients with successful management of acute perforated peptic ulcer by surgical intervention 90% and those with successful management by endoscopy 99% , odds ratio 99%, and risk ratio 2 , so the calculated sample size equal 100 patients divided into two equal groups. Group (1) included 50 patients managed by combined endoscopic & radiologic intervention , group (2) included 50 patients managed by surgery.

Completed2 enrollment criteria

Peptic Ulcer Perforation Study

Peptic Ulcer Perforation

The objective of this study is to implement an optimized perioperative course for patients surgically treated for peptic ulcer perforation in order to improve the outcome for these patients. The optimized perioperative course consists of a number of interventions carried out before, during and after surgery.

Completed4 enrollment criteria

Fast-track Surgery for Perforated Peptic Ulcers

Peptic Ulcer Perforation

The concept of "enhanced recovery after surgery" has become increasingly popular in elective abdominal surgeries. Yet, the role of this concept has not been described in emergency procedures. Therefore, this study aimed to investigate the feasibility of fast-track surgery in patients with perforated peptic ulcer.

Completed15 enrollment criteria

The LAMA Trial: Laparoscopic Correction of Perforated Peptic Ulcer Versus Open Correction

Perforated Peptic Ulcer

This is a multicenter trial comparing laparoscopic correction of a perforated peptic ulcer with the open technique by upper laparotomy. Hypothesis is that after laparoscopic correction will be discharged 3 days sooner due to less postoperative pain and complications.

Completed4 enrollment criteria
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