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Active clinical trials for "Peripheral Vascular Diseases"

Results 921-930 of 1034

RESTORE-IT-Study of Rifalazil in Chlamydia Pneumoniae Seropositive Patients With a History of Atherosclerotic...

Coronary Artery DiseaseCerebrovascular Disease1 more

The objective of this study is to evaluate an antibiotic therapy called Rifalazil to determine its effect on hardening of the carotid arteries.

Unknown status29 enrollment criteria

Effects of Esmolol Infusion on Hemodynamic Responses to Isometric Handgrip

Peripheral Arterial DiseaseAging

This study will test the hypothesis that Esmolol hydrochloride, a beta-1 selective blocker, improves myocardial oxygen (O2) supply-demand balance at rest and during isometric (handgrip) stress in adults with peripheral artery disease (PAD) and healthy controls.

Withdrawn26 enrollment criteria

ACHIEVE GRX Registry

Peripheral Arterial DiseasePeripheral Vascular Diseases2 more

This study will evaluate real-world performance of the CorPath GRX System in peripheral vascular interventions.

Withdrawn8 enrollment criteria

Lower Extremity Regional Anesthesia and Infrainguinal Bypass Grafting

Peripheral Vascular Disease

In this investigation, the investigators will attempt to demonstrate that patients who have received nerve blocks (regional anesthesia) prior to open surgical vascular bypass of the lower extremities (infrainguinal bypass grafting) will have improved surgical outcomes namely a reduction in the rates of death, wound infection, graft thrombosis, graft revision, and amputation. As well, the investigators anticipate that patients who have undergone regional anesthesia for infrainguinal bypass grafting will have improved secondary outcomes with respect to a decreased length of stay, narcotic consumption, nausea and vomiting, post-operative cognitive dysfunction, major cardiac events, post-operative pain, and hyperglycemic episodes.

Withdrawn7 enrollment criteria

Local Paclitaxel Delivery to Prevent Restenosis in Peripheral Arterial Disease

Peripheral Arterial DiseaseRestenosis

The purpose of this study is to determine if the addition of a catheter-based local delivery of paclitaxel into the peripheral arterial vessels in patients with peripheral arterial disease (PAD) and subsequent restenosis of the femoropopliteal region would benefit from this type of investigational intervention with a known antiproliferative agent.

Withdrawn16 enrollment criteria

Effect of Switching From Cigarette Smoking to THS on Systemic Endothelial Function in Subjects With...

Cardiovascular DiseasesSmoking3 more

The purpose of this study is to demonstrate improvement in flow mediated dilation (FMD), a functional endpoint associated with the progression of atherosclerosis, when switching from cigarettes to the Tobacco Heating System (THS) in subjects with peripheral arterial disease (PAD) and/or coronary artery disease (CAD). The study is planned to be conducted in the US, Europe, and Asia.

Withdrawn25 enrollment criteria

Serranator® Alto Post Market Clinical Follow Up (PMCF) Study

Peripheral Arterial DiseaseArterio-venous Fistula1 more

The objective of this registry is to collect observational data under local standard of care and evaluate safety and performance of the Serranator® Alto in treatment of peripheral artery disease (PAD), or dysfunctional native or synthetic arteriovenous dialysis fistulae in a real-world scenario.

Withdrawn2 enrollment criteria

Microparticles and the Risk of Re-stenosis Following Balloon Angioplasty in Patients With Peripheral...

Peripheral Vascular Diseases

Although microparticles have been well-documented as mediators of inflammation and coagulation in various cardio-vascular disease events, it is currently not known how Percutaneous Transluminal Angioplasty (PTA) for peripheral arterial disease influences microparticle numbers, phenotype and distribution pre- and post interventionally and how they are related to or affect the incidence of early re-stenosis - or if indeed they may be used to predict patients at risk of early re-stenosis.

Withdrawn19 enrollment criteria

TRanslesIonal Assessment of Gradients During Endovascular Therapy

Peripheral Arterial DiseaseFractional Flow Reserve1 more

Primary objective: To document change in translesional pressure gradients (TLPGs) and ratios (fractional flow reserve) using the NAVVUS RXi catheter following endovascular treatment for symptomatic lower extremity peripheral arterial disease. Secondary objectives: Evaluation of correlation of the ABI and TBI and TLPGs at baseline and following endovascular therapy Evaluation of the correlation between the change in WIQ, TCOMs, wound size and change in TLPGS Evaluation of correlation between lesion severity by QVA (MLD, % diameter stenosis) and TLPGs Evaluation of baseline MLA, MLD, plaque burden by intravascular ultrasound (optional) and TLPGs

Completed8 enrollment criteria

TurboPower + DCB Treatment of Femoropopliteal De Novo/ Restenotic and In-Stent Restenosis Lesions...

Peripheral Arterial Disease

A retrospective study to evaluate Turbo Power laser atherectomy + drug coated balloon (DCB) angioplasty for the treatment of femoropopliteal de novo/restenotic lesions and in-stent restenosis (ISR).

Completed2 enrollment criteria
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