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Active clinical trials for "Peripheral Vascular Diseases"

Results 941-950 of 1034

Non-Contrast Enhanced Peripheral Magnetic Resonance Angiography

Peripheral Arterial DiseaseIntermittent Claudication1 more

To systematically develop, test, and refine peripheral vascular electrocardiography-gated fast spin echo magnetic resonance imaging for the accurate diagnosis of peripheral arterial disease without gadolinium contrast. To test prospectively the accuracy of fast spin echo in peripheral arterial disease patients, compared with bolus-chase and time-resolved gadolinium enhanced magnetic resonance angiography. Additionally, as a substudy of this project, we will compare our fast spin echo approach with alternative non-contrast-enhanced magnetic resonance imaging methods such as time-of-flight and steady-state gradient echo imaging. The overarching goals of our research are to develop and validate a peripheral magnetic resonance imaging technique that accurately depicts anatomy and disease without exposing patients to exogenous contrast material and its associated risks.

Completed11 enrollment criteria

Ethnicity and Onset of Cardiovascular Disease: A CALIBER Study

Abdominal Aortic AneurysmCoronary Heart Disease12 more

Specific cardiovascular diseases, such as stroke and heart attack, have been shown to vary by ethnic group. However, less is known about differences between ethnic groups and a wider range of cardiovascular diseases. This study will examine differences between ethnic groups (White, Black, South Asian and Mixed/Other) and first lifetime presentation of twelve different cardiovascular diseases. This information may help to predict the onset of cardiovascular diseases and inform disease prevention strategies. The hypothesis is that different ethnic groups have differing associations with the range of cardiovascular diseases studied.

Completed7 enrollment criteria

Evaluating the Occurence of New and Progression of Existing Peripheral Venous Disease in Leg Veins...

Peripheral Vascular Diseases

Peripheral venous disease occurs when a vein becomes damaged or blocked. It can occur almost anywhere in the body, but is most common in the arms and legs. This study will examine people who participated in a previous venous disease study to evaluate changes in leg veins and venous disease status over a period of 11 years.

Completed1 enrollment criteria

Objective Evaluation of Proximal Ischemia

Intermittent ClaudicationPeripheral Vascular Diseases

The whole study is divided in 4 parallel protocols. The first protocol estimates the reliability of the technique through test-retest recordings. The second protocol aims to prove that exercise Tcpo2 is efficient to estimate the benefit of proximal revascularisation on proximal and distal ischemia in patients suffering stage two lower extremity arterial disease. The third protocol aims at estimating with exercise tcpo2 the eventual apparison of proximal ischemia after aorto-bi-femoral bypasses. The last protocol is a transversal study of patients with aorto-bi-femoral bypasses aiming to analyse the presence of proximal and distal symptoms and ischemia. The hypothesis for protocol 2 is that TcpO2 at exercise is significantly improved after surgery at the aortic and primary iliac artery. The hypothesis for protocols 3 and 4 relates on the hypothesis that a significant number of patients benefiting aorto-bi-femoral bypass suffer isolated proximal pain/ischemia after surgery. Amendement to the project has been recently validated to study the neurologic and bone complication of chronic vascular ischemia

Completed8 enrollment criteria

Angio-Seal Evolution Device Registry

Peripheral Vascular DiseaseCoronary Artery Disease3 more

Collect data on the use of the Angio-Seal Evolution Device in diagnostic and interventional patient populations.

Completed2 enrollment criteria

RISE: A Clinical Evaluation of the StarClose™ Vascular Closure System

Peripheral Vascular DiseaseCardiovascular Disease

To evaluate early ambulation in patients who receive the StarClose™ VCS post-percutaneous diagnostic procedure.

Completed40 enrollment criteria

Etiology and Prevalence of Peripheral Arterial Disease

Cardiovascular DiseasesPeripheral Vascular Diseases1 more

To determine the prevalence of peripheral arterial disease in a defined population by non-invasive techniques; to evaluate the association of cardiovascular disease risk factors with peripheral vascular disease; to determine whether non-invasive tests of peripheral arterial disease can be utilized as markers for coronary heart disease; to determine the status of the microvasculature using conjunctival photographs and to compare the results with risk factors and the peripheral arterial disease testing results.

Completed1 enrollment criteria

Comparison of Huntleigh Dopplex DMX Digital Doppler Arterial Waveform With the Gold Standard of...

UltrasonographyDoppler1 more

NICE guidelines recommend an Ankle brachial pressure index (ABPI) as the primary assessment tool for patients presenting with symptoms or are at a high risk of developing peripheral arterial disease (PAD). An ABPI is typically performed using a hand-held Doppler to listen and classify the arterial signal in the ankle and arm and the systolic pressure is taken in each to create a ratio of the pressure in the ankle to the arm. New Huntleigh Dopplex DMX Digital Dopplers within the vascular department have an arterial waveform display to help interpretation of the audible signal. This study aims to compare the audible and visual waveform traces on the Huntleigh Dopplex with the gold standard of ultrasound duplex to assess the accuracy of the trace using diagnostic measurements and the ability of clinicians to correctly identify audible and visual waveforms.

Completed8 enrollment criteria

HRQoL Among Patients Amputated Due to Peripheral Arterial Disease

Quality of LifeAmputation2 more

A prospective cohort study over the prosthetic use among patients amputated after vascular disease and the impact of their HRQoL.

Completed4 enrollment criteria

Non-invasive Computer-Aided Phenotyping of Vasculopathy

Carotid AtherosclerosisPeripheral Arterial Disease

The investigators use MRI and/or CT to evaluate the extent, as well as, the structure, composition, and functional aspects of atherosclerotic plaques in human carotid and femoral arteries in patients scheduled to undergo an endarterectomy of the aforementioned vascular beds as part of their routine clinical care.

Completed9 enrollment criteria
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