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Active clinical trials for "Phobia, Social"

Results 241-250 of 284

CHI-902 for Treatment of Social Anxiety Disorder

Social Anxiety Disorder

No substantial clinical trials of Cannabidiol (CBD) in Social Anxiety Disorder (SAD) have yet been conducted. This randomized doubleblind, placebo-controlled trial of CBD in adults with SAD will evaluate the efficacy, tolerability and safety of CBD oil (CHI-902) in SAD. In addition, the effects of treatment with CHI-902 on the Endocannabinoid System (ECS) will be assessed by evaluating peripheral endocannabinoids (Arachidonoylethanolamide/Anandamide (AEA) and 2-Arachidonoyl glycerol (2-AG)) before and after treatment.

Withdrawn19 enrollment criteria

Cerebellar Neuromodulation to Enhance Fear Extinction and Predict Response to Exposure Therapy

Anxiety DisordersSocial Phobia

Emerging neuroimaging studies have shown that the cerebellum contributes to different aspects of timing, prediction, learning, and extinction of conditioned responses to aversive stimuli, factors that may be relevant to the success of exposure based behavioral therapy. Our goals are to determine the cerebellar contributions to fear extinction by attempting to modulate key pathways in this process by theta burst stimulation. The long term goal is to lay the foundation for future studies in which neuromodulation is used to augment exposure therapy.

Completed3 enrollment criteria

Integrated Mental Health Care and Vocational Rehabilitation to Individuals on Sick Leave Due to...

Generalized AnxietySocial Phobia2 more

The purpose of this study is to investigate the efficacy of 1) a stepped mental health care intervention and 2) an integrated mental health care and vocational rehabilitation intervention for people on sick leave because of depression and anxiety in Denmark

Completed15 enrollment criteria

Predicting Treatment Response to Exposure Therapy Using Carbon Dioxide

Generalized Anxiety DisorderSocial Anxiety Disorder2 more

Anxiety disorders affect over a quarter of the population, yet very little is known about the variables that predict treatment outcome. The planned study explores whether a patient's response to a physiological test involving inhalation of carbon dioxide predicts their response to exposure therapy.

Completed12 enrollment criteria

Acute Anxiolytic Effects of Riluzole on Subjects With Social Anxiety Disorder

Social Anxiety DisorderPerformance Anxiety

The goal of the current proposal is to examine if sublingual riluzole can reduce anxiety in people with social anxiety disorder during a public speaking task.

Completed21 enrollment criteria

Pilot Study: VR Mind and VR Mind+ Intervention

Social Phobia

The aim of the pilot study is feasibility, usability and safety assessment of VR Mind intervention. In particular the subject of assessment will be: the length of the laboratory session utilizing virtual reality exposure (feasibility), the ergonomics and ease of use for both patients and system operators (usability), the frequency of side effect occurrence as a result of virtual reality exposure (ie. Vertigo) (safety). The results pilot study will be used in the designing a clinical trial aimed for testing efficacy and safety of VR Mind intervention.

Completed18 enrollment criteria

Assessing Mechanisms of Anxiety Reduction in Animal-assisted Interventions

Social Anxiety DisorderSocial Anxiety1 more

Adolescence and young adulthood is a critical period for the development of social anxiety, which is often linked to other mental health challenges such as depression, mood disorders, and substance abuse. Initial evidence suggests that interacting with animals can reduce stress and anxiety, but no research has tested whether this benefit extends to adolescents at risk for social anxiety disorder. Additionally, researchers and clinicians do not understand what mechanism is responsible for anxiety reduction in animal-assisted interventions (AAIs). Therefore, the objectives of this study are to explore the specific mechanisms by which interacting with a therapy dog reduces anxiety, and to test whether such an interaction reduces anxiety in adolescents with varying levels of social anxiety.

Completed3 enrollment criteria

Cognitive Biases Modification Treatment for Social Anxiety

Social Phobia

Adults with Social Phobia will be randomly assigned to either an attention bias modification treatment, interpretation bias modification treatment, both, or a placebo control condition not designed to change cognitive bias patterns. Outcome measures will be social anxiety symptoms and severity as measured by gold standard questionnaires as well as diagnosis of social phobia disorder and symptom counts derived from structured clinical interviews based on DSM-IV criteria. The investigators expect to find significant reduction in social anxiety symptoms in the Treatment groups relative to the placebo control group. The investigators want to find out the relative efficacy of attention and interpretation oriented treatments and the combination of the two.

Completed2 enrollment criteria

Examining the Effects of Reduced Environmental Stimulation on Anxiety

Generalized Anxiety DisorderAgoraphobia4 more

The studies proposed in this protocol aim to explore the anxiolytic properties of floating as it relates to the central and autonomic nervous system.

Completed19 enrollment criteria

Brain Plasticity and Cellular Aging After Internet-delivered CBT for Social Anxiety Disorder

Anxiety DisordersSocial Anxiety Disorder

This study evaluates underlying psychological and biological mediators in Internet-delivered cognitive behavior therapy for adults with social anxiety disorder.

Unknown status19 enrollment criteria
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