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Active clinical trials for "Rhinitis, Allergic, Seasonal"

Results 271-280 of 365

A Study of Onset of Action of Loratadine and Fexofenadine in Participants With Seasonal Allergic...

Rhinitis

The purpose of this study is to determine the onset of action of two commercially available over-the-counter antihistamines (Loratadine and Fexofenadine) in a model of seasonal allergic rhinitis (SAR). Participants undergo sensitization exposures to Mountain Cedar (juniperus ashei) pollen in a Biogenics Research Chamber; those who demonstrate an adequate allergic response determined by the Major Symptom Complex (MSC) score will then receive drug.

Completed13 enrollment criteria

MP-AzeFlu Allergen Chamber - Onset of Action Study

Seasonal Allergic Rhinitis

This study is to assess the onset of action of fixed drug combination of azelastine hydrochloride and fluticasone propionate nasal spray (MP-AzeFlu) in treating the nasal symptoms of seasonal allergic rhinitis (SAR) induced by an allergen challenge in an Environmental Exposure Chamber (EEC).

Completed36 enrollment criteria

A Study To Explore The Effect On Inflammatory Markers After Nasal Allergen Challenge In Subjects...

Allergic Rhinitis

After a nasal allergen challenge it should be possible to measure markers of inflammation that may be useful to assess the properties of future drugs. If these markers are reproducible and impacted by the study drugs they could be useful for future drug development.

Completed5 enrollment criteria

Montelukast as a Controller of Atopic Syndrome

Seasonal Allergic RhinitisAllergic Conjunctivitis2 more

The purpose of the study is to find out if montelukast can be used to treat the various symptoms of allergic syndrome.

Completed10 enrollment criteria

Study In Adolescent And Adult Subjects 12 Years Of Age And Older With Seasonal Allergic Rhinitis...

RhinitisAllergic1 more

Allergic rhinitis is an inflammatory disorder of the upper airway that occurs following allergen exposure. The focus of this study, seasonal allergic rhinitis (SAR), is one type of allergic rhinitis that is triggered by the pollen from trees, grasses, and weeds. Commonly referred to as "hay fever", it is characterized by sneezing, nasal congestion and pruritus, rhinorrhea, and pruritic, watery, red eyes. The purpose of this study is to evaluate the onset of action of an investigational nasal spray, GW685698X aqueous nasal spray, versus vehicle placebo nasal spray in the treatment of seasonal allergic rhinitis caused by ragweed following a single dose of treatment in controlled pollen concentrations in an allergen challenge chamber.

Completed12 enrollment criteria

Montelukast in Seasonal Allergic Rhinitis - Fall 1999 Study (0476A-117)

Seasonal Allergic Rhinitis

This study will evaluate the ability of oral montelukast/loratadine to improve the signs and symptoms of seasonal allergic rhinitis compared with loratadine alone, montelukast alone and placebo.

Completed11 enrollment criteria

Specific Immunotherapy With Recombinant Birch Pollen Allergen rBet v1-FV

Birch Pollen Allergy

Specific immunotherapy with recombinant birch pollen allergen rBet v1-FV

Completed5 enrollment criteria

Clinical Equivalence Study of Fluticasone Propionate Nasal Spray, 50 mcg/Actuation vs. Flonase in...

Seasonal Allergic Rhinitis

This double-blind, randomized, placebo-controlled, parallel group, multi-site study has been designed to compare the safety and efficacy of a generic Fluticasone propionate Nasal Spray, 50 mcg (Teva Pharmaceuticals USA) to the FDA Reference Listed Drug, Flonase® (fluticasone propionate) 50 mcg nasal spray (GlaxoSmithKline), in the relief of the signs and symptoms of Seasonal Allergic Rhinitis. Additionally, both the test and reference formulations will be tested for superiority against a placebo nasal spray.

Terminated42 enrollment criteria

Clinical Efficacy and Safety of gpASIT+TM to Treat Seasonal Allergic Rhinoconjunctivitis

Grass Pollen AllergyHay Fever

The purpose of the study is to evaluate the efficacy and safety of grass pollen-derived peptides administrated orally to treat seasonal allergic rhinoconjunctivitis.

Completed32 enrollment criteria

Glycyphagus Domesticus Allergen Extract. Determination of the in Vivo Biological Activity in Histamine...

RhinitisAllergic3 more

The main purpose of the trial is to prove the therapeutic value of the product and enable an effective and safe dosage schedule to be recommended

Completed14 enrollment criteria
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