Random Urine Protein-creatinin Ratio to Predict Magnitude of Proteinuria
Pre-eclampsiaThe aim of this study was to evaluate diagnostic accuracy of the spot urinary proteinuria, random urine protein- creatinin ratio for prediction of significant proteinuria (≥ 300 mg/24h) and magnitude of proteinuria in patients with in mild preeclampsia and severe preeclampsia. The cross-sectional longitudinal study design used, 209 patients with pre-diagnosed preeclampsia in which in our inpatients clinic included this study. Random urine samples were taken before the 24 hour urine collection for spot urine analysis for evaluated proteinuria and protein/creatinin ratio. 24 hour urine analysis was performed in all patients as the gold standard of the urine total proteinuria.
Collection of Whole Blood Samples for the Evaluation of Preeclampsia (Pre-E) Biomarkers From Pregnant...
Pre-EclampsiaHypertension7 moreWhole blood sample procurement study from pregnant women with signs and symptoms of Preeclampsia.
TTP and aHUS in Complicated Pregnancies
Thrombotic Thrombocytopenic PurpuraAtypical Hemolytic Uremic Syndrome6 moreA single site observational study aiming to: (i) Identify cases of previously undiagnosed thrombotic thrombocytopenic purpura (TTP) and atypical haemolytic syndrome (aHUS) in a cohort of women with complicated pregnancies (ii) Characterise the clinical features of these cases and (ii) Identify clinical features or biomarkers which may help distinguish TTP/aHUS from other complications of pregnancy such as preeclampsia
Blood Loss and Preeclampsia
Pre-Eclampsia; Complicating PregnancyBlood Loss1 moreStudy of blood loss in preeclamptic patients using mathematical formulae
Longitudinal Study: Diagnosis and Prediction of Pre-Eclampsia by Using Congo Red Dot Test in Bangladesh...
PreeclampsiaA population-based prospective cohort design will evaluate the progression of urine congophilia in pregnancy using the Congo Red Dot test by following patients longitudinally across gestation in Bangladesh and Mexico City.
Pancreatic Stone Protein (PSP) in Pregnant Women
PregnancyHELLP Syndrome2 moreThis prospective, single centred cohort study evaluates the physiological course of the potentially novel biomarker PSP in pregnant women as well as its predictive role in the development of inflammatory complications during pregnancy.
uChek Pilot Study for Urinalysis in the Antenatal Care Setting
PreeclampsiaEclampsia2 moreA prospective observational study to test the feasibility of smartphone enabled uChek urinalysis device to detect biomarkers (protein, microalbumin and protein:creatine ratio) in urine, indicative of preeclampsia/eclampsia at over 22 weeks of gestation and assess attitudes of clinicians towards uChek as a new technology for urinalysis.
Preeclampsia Subtypes and Surrogate Markers of CVD Risk
PreeclampsiaIn order to assess surrogate markers of cardiovascular risk in subtypes of preeclampsia, we will conduct a 10-year follow-up study comparing 40 women with a history of early onset preeclampsia; 40 women with a history of late onset preeclampsia and 40 women with a history of normotensive pregnancies. Eligible participants delivered at the Department of Obstetrics at Randers Regional Hospital 1998-2008. Early-onset preeclampsia is defined as preeclampsia that develops before 34 weeks of gestation, whereas late-onset preeclampsia develops at or after 34 weeks of gestation.
Nicardipine and Labetalol Effects on Cerebral Hemodynamics in Preeclampsia
Preeclampsia SevereRealization of transcranial doppler and optic nerve sheath in severe preeclamptic patients to evaluate the impact of nicardipine and labetalol on cerebral hemodynamics.
Prediction of Early Pre-eclampsia From Maternal Factors, Biophysical and Biochemical Markers at...
Pre-EclampsiaThe aims of this study are to develop algorithms based on a combination of maternal factors, uterine artery PI, MAP and serum biomarkers to estimate patient-specific risks for early Preeclampsia (PE) and to evaluate the screening performance of such algorithms in twins.