Active clinical trials for "Premature Birth"

The primary objective is to assess the burden of respiratory disease in outpatient settings among 32 to 35 weeks' gestational age (wGA) infants in the USA who did not receive RSV prophylaxis during the infants' first RSV season.

The prevalence of preterm birth is not decreasing in the last decades despite of improving health care. Intrauterine infections are important in the etiology of preterm birth but the interconnection of systemic inflammation and preterm birth is not clear. Mechanisms of preterm birth should be assessed as preterm birth is the major risk factor for morbidity and mortality during birth, thus being important for the individual and regarding health costs. No interventions will be carried out in this study. Hypotheses: There is a common etiology between oral and vaginal inflammation Bacterial species are similar in vagina and oral cavity There are similar oral and systemic immune reactions which provoke preterm birth Inflammatory markers are found in pregnant women at risk and get back to normal post partum In this matched case control study of pregnant women local, systemic and oral inflammation markers and bacterial load are assessed to find out interconnections between these body compartments to allow for explanation of the etiology of preterm birth.

The purpose of this study is to determine if there is a relationship between time spent out the targeted oxygen saturation range in preterm infants is associated with long-term outcomes such as Retinopathy of Prematurity.

The purpose of this study is to investigate the expression of protein biomarkers in cervical vaginal fluid in women with preterm premature rupture of membranes (PPROM)

The study included analysis of longitudinal recordings of amplitude-integrated EEG (aEEG) tracings on a weekly basis in preterm infants and evaluation of their neurodevelopmental outcome at the age of three years. Aim of the study was to observe if there is a correlation of the aEEG tracings of the first weeks of life to later neurodevelopmental outcome and to evaluate if aEEG can be used as prognostic tool.

Amniotic Fluid "Sludge" Does Not Increase Risk of Preterm Delivery in Cerclage Patients.

The purpose of this study is to to collect and store blood samples that will be utilized to develop a multimarker test to predict preterm delivery.

The purpose of this study is to determine whether the immediate bolus strategy combined with early nasal CPAP (nCPAP) treatment could decrease the subsequent need for ventilation compared to the administration of surfactant prophylaxis at 15 minutes after birth with early nCPAP in premature infants.

Women who are affected with premature ovarian failure will exhibit skewed X-chromosome inactivation patterns compared to women with normal menstrual function (as defined by being pregnant), indicating a possible X-chromosome defect.

Assess the burden of disease associated with RSV infection with premature children in an outpatient setting.