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Active clinical trials for "Obstetric Labor, Premature"

Results 81-90 of 234

Evaluation of the Use of Indomethacin as Co-treatment in Women With Preterm Labor and High Risk...

Preterm Labor With Intact Membranes

To demonstrate if indomethacin associated to conventional treatment for preterm labor is useful to delay delivery and to improve neonatal morbimortality in women with preterm labor with high risk of intraamniotic inflammation

Completed13 enrollment criteria

Absorption, Distribution, Metabolism And Excretion Study For GSK221149A

Obstetric LabourPremature1 more

This is a phase one study investigating the absorption, distribution, metabolism and excretion of GSK221149A in six healthy women of non-child bearing potential.

Completed6 enrollment criteria

Ritodrine in Oral Maintenance of Tocolysis After Active Preterm Labor

Pregnancy

This is a trial comparing the efficacy of oral ritodrine in the form of sustained release capsules for the maintenance of uterine quiescence after successfully treated episode of threatened preterm labor.

Completed8 enrollment criteria

Vaginal PROgesterone as Maintenance Treatment After an epISode of prEterm Labor (PROMISE Study)...

Threatened Premature Labor

Eligible patients will be informed and asked to enroll in the study at hospital admission. A transvaginal ultrasound examination will be performed to determine cervical length. If an eligible woman accepts to participate, patient will be randomized to one of the study arms assigned in a double blind basis. Patient will receive the medication (vaginal capsule of progesterone or placebo). The patient will administer herself one vaginal capsule in a daily basis since gestational age of 36 weeks and 6 days as the primary endpoint is to demonstrate that the use of a maintenance treatment with vaginal progesterone is able to reduce the incidence of preterm birth before 34.0 and 37.0 gestational weeks. After delivery, perinatal and neonatal data will be collected.

Completed15 enrollment criteria

Vaginal Progesterone Supplementation in the Management of Preterm Labor

Preterm Labor

This study evaluates the addition of vaginal progesterone in the management of preterm labor. Half of participants will receive vaginal progesterone, tocolysis and corticosteroid, while the other half will receive only tocolysis and corticosteroid.

Completed7 enrollment criteria

Early Labour Assessment and Support at Home

Latent Phase Labour

To determine, among healthy first time mothers who are uncertain as to when to come to hospital in labour, if home visits by obstetrical nurses compared to telephone advice have an impact on reducing cesarean section rate.

Completed10 enrollment criteria

Analyze Changes in Respiratory Rate When Using the Scare Respirator

Apnea of NewbornPreterm Labor

Pilot study of 10 preterm, who are going to be randomly placed to 3 phases : 2 hour of basal observation of respiratory rate, heart rate, saturation, NIPS and aEEG recording, 2 hours with a 20cycles/minute with "scare ventilator", and 2 hours of 40 cycles/minute with "scare ventilator"

Completed4 enrollment criteria

COVID-19-associated Anxiety of Pregnant Women for Anomalies, Stillbirth and Preterm Labor-2

Anxiety State

Capture of anxiety for anomalies, stillbirth and preterm labor of pregnant women during COVID-19 pandemia

Active3 enrollment criteria

Oral Versus Parental Progesterone in the Management of Preterm Labor

Preterm Labor

Preterm birth, defined as delivery at less than 37 weeks gestation, complicates approximately 12% of pregnancies in the United States Preterm delivery has been, and remains, the most important challenge to modern obstetrics. In 2009, 13 million babies were born preterm, 11 million in Africa and Asia and 500,000 in the USA, The highest rates of preterm birth are in Africa (11.9%) and North America (10.6%)

Completed8 enrollment criteria

MIRACLE of LIFE Study

Preterm LaborPreterm Birth8 more

The goal of this observational study is to develop and validate cell-free RNA-based biomarkers for predicting a variety of adverse pregnancy outcomes in a pregnant person population. The main question it aims to answer are: Can cell-free RNA-based biomarkers predict which pregnant people are at greatest risk of developing adverse pregnancy outcomes (e.g., preterm birth, preeclampsia)? What is the performance of such biomarkers when predicting an adverse pregnancy outcome (e.g., sensitivity, specificity, PPV, NPV, TPR)?

Active7 enrollment criteria
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