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Active clinical trials for "Primary Immunodeficiency Diseases"

Results 161-170 of 177

Real-world CANadian CUvitru Non-Interventional Study in Subjects Transitioning From Subcutaneous...

Primary Immunodeficiency Diseases (PID)

This study will provide insights on the infusion parameters, dosing, and experience of participants transitioning to CUVITRU in a real-world setting.

Completed7 enrollment criteria

Primary Immunodeficiencies in Costa Rican Adults

Primary Immune Deficiency in Adults

Primary immunodeficiencies represent a underdiagnosed group of rare diseases which if diagnosed well and in time can be treated in an efficient manner and prevent complications that may affect the quality of patients life in an severe manner. Neither in Costa Rica nor in Central America studies or national registries regarding the prevalence and characterization of primary immunodeficiencies in adult patients exist up to now. This study reflects for the first time the epidemiologic situation of primary immunodeficiencies in a Central American country, characterizing adult patients diagnosed with primary and idiopathic immune disorders treated in two specialized immunodeficiency clinics in Costa Rica.

Completed3 enrollment criteria

What is the Incidence of an Immune Disorder in Children With Invasive Pneumococcal Disease (IPD)?...

Invasive Pneumococcal DiseaseRecurrent Isolated7 more

This is a multicentre prospective audit to determine the incidence of immunodeficiency in children with IPD. Aims and/or research question of the project To determine the incidence of primary immunodeficiency in children >2 years who present with IPD To determine the types of immunodeficiency associated with IPD in children

Completed3 enrollment criteria

Diagnostic Immunization With Rabies Vaccine in Patients With PID

Primary Immunodeficiency

The purpose of this study is to evaluate diagnostic immunization protocol of rabies vaccine for diagnosis the patients with primary immunodeficiency disorders and study humoral and cellular immune response to rabies vaccine in patients with primary immunodeficiency.

Unknown status16 enrollment criteria

Clinical and Laboratory Online Patient- and Research Database for Primary Immunodeficiencies in...

Primary Immunodeficiency Disease

A Swiss national, multi-centre, online patient and research database will be created, using the existing ESID database server system. This database contains disease-specific data from patients with primary (inborn) immunodeficiency diseases (PID).

Unknown status2 enrollment criteria

Rituximab and Abatacept Effectiveness in Differential Treatment of Interstitial Lymphocytic Lung...

Interstitial Lymphocytic Lung Disease

The rationale for this retrospective study is to evaluate the efficacy and safety of abatacept and rituximab treatment of ILLD in a cohort of pediatric patients with different forms of PID, who received one of the two therapy regimens predominantly based on the lesions histopathology.

Unknown status4 enrollment criteria

COVID-19 Vaccine in Patients After Allogeneic HCT, CAR-T Therapy and With Primary Immune Deficiency...

Allogenic Hematopoietic Cell TransplantCAR-T Therapy1 more

The corona pandemic is a continuing global challenge due to Corona Virus 2019 (COVID-19). The purpose of the study is to confirm the accepted hypothesis from the recommendations of The European Society for Blood and Marrow Transplantation, that the vaccine for COVID-19 is safe and has good efficacy in immunocompromised patients after a bone marrow transplant from a donor / cellular therapy.

Unknown status14 enrollment criteria

Expanded Access Protocol for Tabelecleucel for Patients With Epstein-Barr Virus-Associated Viremia...

Epstein-Barr Virus (EBV) InfectionsLymphoproliferative Disorders11 more

The primary objective of this protocol is to provide expanded access to tabelecleucel to participants with Epstein-Barr virus-associated diseases and malignancies for whom there are no other appropriate therapeutic options, and who are not eligible to enroll in clinical studies designed to support the development and registration of tabelecleucel.

No longer available23 enrollment criteria

Determinants of Health Status and Quality of Life in Patients With Primary Immunodeficiencies Inhereted...

Primary Immune Deficiency

Background: Most children with primary immune deficiency (PID) now reach adulthood. However, few studies have evaluated their health status and health related quality of life (HRQoL). Objective: To investigate long-term morbidity, the French Reference Center for PIDs initiated a prospective multicenter cohort: the F-CILC (French Childhood Immune deficiency Long-term Cohort). The data collected will be used to assess the physical health condition of patients who reached adulthood and the impact on their quality of life. Methods: Patients are asked to complete health status questionnaires. A severity score (grade1 ["mild"] to grade 4 ["life-threatening"]) is assigned to each health condition. The HRQoL of patients is compared to age- and sex-matched French normal values using the SF36 HRQoL questionnaire. Capsule summary. This will be the first study of adult survivors of childhood PID describing how the burden of health conditions affect their quality of life.

Unknown status2 enrollment criteria

Genetic Study of Immunodeficiency: Search for New Genetic Causes for Primary Immunodeficiencies...

Immunologic Deficiency Syndromes

Individuals with suspected primary immunodeficiency will be studied and the results compared with healthy controls. Primary immunodeficiency may manifest as recurrent, severe or unusual infections as well as signs and symptoms of immune dysregulation such as autoimmunity or lymphoproliferation.

Unknown status3 enrollment criteria
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