Vancomycin for Primary Sclerosing Cholangitis
Primary Sclerosing CholangitisTo find out if vancomycin is a safe and effective therapy for primary sclerosing cholangitis. Funding Source - FDA OOPD
CS0159 in Chinese Patients With PSC (Primary Sclerosing Cholangitis)
Primary Sclerosing CholangitisA phase II Study of CS0159 in Chinese patients with PSC(Primary Sclerosing Cholangitis)
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With...
Primary Sclerosing CholangitisThe purpose of this clinical research study is to learn more about the use of the study medicine, volixibat, for the treatment of pruritus (itching) associated with Primary Sclerosing Cholangitis (PSC), and to assess the possible impact on the disease progression of PSC.
Efficacy of 24 Month of Bezafibrate in Primary Sclerosing Cholangitis With Persistent Cholestasis...
Primary Sclerosing CholangitisCholestasisThe objectives of this study are to evaluate the effect of bezafibrate treatment compared to placebo on efficacy and safety in patients with primary sclerosing cholangitis (PSC) and persistent cholestasis despite ursodeoxycholic acid therapy
Safety and Tolerability of A3907 in Primary Sclerosing Cholangitis
Primary Sclerosing CholangitisThis study will test a drug called A3907 to see how safe and tolerated it is for treating people with Primary Sclerosing Cholangitis (PSC).
Sulfasalazine for the Treatment of Primary Sclerosing Cholangitis
Primary Sclerosing CholangitisThis is a multicenter, randomized, double-blinded placebo controlled trial to assess the benefit of sulfasalazine in the treatment of PSC. The specific objectives of this study are to determine if sulfasalazine treatment 1) results in reduced serum ALP and other biomarkers of liver injury in PSC; 2) improves PSC patient symptoms; and 3) is safe in patients with PSC.
Study to Evaluate EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis...
PruritusThis phase 2 trial will evaluate the effects of EP547 in subjects with cholestatic pruritus due to Primary Biliary Cholangitis (PBC) or Primary Sclerosing Cholangitis (PSC)
norUrsodeoxycholic Acid vs Placebo in PSC
Primary Sclerosing CholangitisDouble-blind, randomized, multi-center, placebo-controlled, comparative, phase III trial. The study will be conducted with two treatment groups in the form of a parallel group comparison and will serve to compare oral treatment with either 1500 mg/d norursodeoxycholic acid capsules or placebo capsules for the treatment of Primary Sclerosing Cholangitis.
Detection of Integrin avb6 in IPF, PSC, and COVID19 Using PET/CT
Idiopathic Pulmonary FibrosisPrimary Sclerosing Cholangitis1 moreDetection of Integrin avb6 in Idiopathic Pulmonary Fibrosis, Primary Sclerosing Cholangitis, and Coronavirus Disease 2019 with [18F]FP-R01-MG-F2 with PET/CT
Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study
Primary Sclerosing CholangitisInflammatory Bowel DiseasesPSC is a liver disease that has no medical cure. Patients with PSC are at a greatly increased risk of cancer and infection. Additionally, many patients require a liver transplant. Progress towards a cure has been severely limited by an incomplete understanding of why patients develop PSC. The investigators aim to close this gap by conducting a pilot human study in patients with PSC, using statin therapy as a model
