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Active clinical trials for "Psoriasis"

Results 981-990 of 1714

Effect of Sublimated Mare Milk Supplement on Gut Microbiome in Psoriasis Patients

Psoriasis

This study evaluates the effect of dietary supplement consisting of sublimated mare milk on intestinal microbiota among psoriasis and healthy participants.

Completed12 enrollment criteria

Safety and Pharmacokinetics of Sustained-release Depot Tacrolimus: A First-in-human Study

Organ Transplant RejectionPsoriasis

This first-in-human study is designed to assess the safety and pharmacokinetic (PK) profile of sustained-release (SR) depot tacrolimus, which will be administered as a single dose of 0.1 mg/kg by subcutaneous (SC) injection in healthy subjects.

Completed29 enrollment criteria

A Study to Investigate the Safety, Tolerability, Pharmacokinetic, and Efficacy of ABY-035/AFO2

Psoriasis

The purpose of this first-in-human study of the formulation ABY-035/AFO2 is to investigate the safety, tolerability and efficacy after multiple doses in sequential escalating dose cohorts in psoriasis subjects.

Completed10 enrollment criteria

Autologous Natural Killer Cells in Subjects With Plaque Psoriasis

Plaque Psoriasis

This is a non-randomized, dose escalating and open-labeled clinical trial to evaluate the safety of autologous natural killer cell (NK) infusions (IV) of "SNK01" in adults with plaque psoriasis. The primary objective of this study is to investigate the safety and tolerability of four infusions of "SNK01" in subjects with plaque psoriasis. Secondary objective is preliminary efficacy of "SNK01" in subjects with plaque psoriasis.

Completed24 enrollment criteria

To Evaluate the Therapeutic Equivalence and Safety in Treatment of Scalp Psoriasis

Scalp Psoriasis

To demonstrate the superiority of the efficacy of the test and reference products over that of the placebo control in the treatment of scalp psoriasis.

Completed7 enrollment criteria

A Study to Assess Usability of Risankizumab Autoinjector Combination Product in Participants With...

Psoriasis

The objectives of this study were to evaluate the usability of the combination product of risankizumab in an autoinjector (AI), as well as to evaluate the efficacy, safety, and tolerability of risankizumab administered by AI for the treatment of adult participants with moderate to severe plaque psoriasis.

Completed7 enrollment criteria

A Phase 3B, Open-label, Single-arm Study of the Efficacy and Safety of Apremilast, in Subjects With...

Plaque Psoriasis

The primary objective of the study is to assess the efficacy and safety of the combination of apremilast plus topical therapies for the treatment of adults with plaque psoriasis who have not achieved an adequate response with topicals alone.

Completed33 enrollment criteria

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Repeat Topical Administration...

Psoriasis

This study was conducted to evaluate the safety and tolerability of BOS-475 following single and repeat topical administration to healthy participants (Part A), and to evaluate the safety and tolerability of 42-day repeat topical administration of BOS-475 to participants with plaque psoriasis (Part B).

Completed38 enrollment criteria

A Study to Evaluate RIST4721 in Palmoplantar Pustulosis (PPP)

Palmoplantar Pustulosis

A Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study to Evaluate the Efficacy and Safety of RIST4721 in Subjects with Palmoplantar Pustulosis

Completed7 enrollment criteria

A Study to Evaluate the Safe and Effective Use of the Prefilled Safety Syringe or the Auto-injector...

Chronic Plaque PsoriasisModerate to Severe Chronic Plaque Psoriasis

The purpose of the study is to evaluate the ability of subjects with moderate to severe chronic plaque psoriasis (PSO) to safely and effectively self-inject bimekizumab at study start and 8 weeks after training in self-injection technique using a prefilled safety syringe or an auto-injector.

Completed3 enrollment criteria
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