
Effect of Sublimated Mare Milk Supplement on Gut Microbiome in Psoriasis Patients
PsoriasisThis study evaluates the effect of dietary supplement consisting of sublimated mare milk on intestinal microbiota among psoriasis and healthy participants.

Safety and Pharmacokinetics of Sustained-release Depot Tacrolimus: A First-in-human Study
Organ Transplant RejectionPsoriasisThis first-in-human study is designed to assess the safety and pharmacokinetic (PK) profile of sustained-release (SR) depot tacrolimus, which will be administered as a single dose of 0.1 mg/kg by subcutaneous (SC) injection in healthy subjects.

A Study to Investigate the Safety, Tolerability, Pharmacokinetic, and Efficacy of ABY-035/AFO2
PsoriasisThe purpose of this first-in-human study of the formulation ABY-035/AFO2 is to investigate the safety, tolerability and efficacy after multiple doses in sequential escalating dose cohorts in psoriasis subjects.

Autologous Natural Killer Cells in Subjects With Plaque Psoriasis
Plaque PsoriasisThis is a non-randomized, dose escalating and open-labeled clinical trial to evaluate the safety of autologous natural killer cell (NK) infusions (IV) of "SNK01" in adults with plaque psoriasis. The primary objective of this study is to investigate the safety and tolerability of four infusions of "SNK01" in subjects with plaque psoriasis. Secondary objective is preliminary efficacy of "SNK01" in subjects with plaque psoriasis.

To Evaluate the Therapeutic Equivalence and Safety in Treatment of Scalp Psoriasis
Scalp PsoriasisTo demonstrate the superiority of the efficacy of the test and reference products over that of the placebo control in the treatment of scalp psoriasis.

A Study to Assess Usability of Risankizumab Autoinjector Combination Product in Participants With...
PsoriasisThe objectives of this study were to evaluate the usability of the combination product of risankizumab in an autoinjector (AI), as well as to evaluate the efficacy, safety, and tolerability of risankizumab administered by AI for the treatment of adult participants with moderate to severe plaque psoriasis.

A Phase 3B, Open-label, Single-arm Study of the Efficacy and Safety of Apremilast, in Subjects With...
Plaque PsoriasisThe primary objective of the study is to assess the efficacy and safety of the combination of apremilast plus topical therapies for the treatment of adults with plaque psoriasis who have not achieved an adequate response with topicals alone.

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Repeat Topical Administration...
PsoriasisThis study was conducted to evaluate the safety and tolerability of BOS-475 following single and repeat topical administration to healthy participants (Part A), and to evaluate the safety and tolerability of 42-day repeat topical administration of BOS-475 to participants with plaque psoriasis (Part B).

A Study to Evaluate RIST4721 in Palmoplantar Pustulosis (PPP)
Palmoplantar PustulosisA Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study to Evaluate the Efficacy and Safety of RIST4721 in Subjects with Palmoplantar Pustulosis

A Study to Evaluate the Safe and Effective Use of the Prefilled Safety Syringe or the Auto-injector...
Chronic Plaque PsoriasisModerate to Severe Chronic Plaque PsoriasisThe purpose of the study is to evaluate the ability of subjects with moderate to severe chronic plaque psoriasis (PSO) to safely and effectively self-inject bimekizumab at study start and 8 weeks after training in self-injection technique using a prefilled safety syringe or an auto-injector.