Dose Finding of Quetiapine Fumarate 200mg vs 400mg in First Episode Psychosis
PsychosisThe purpose of this study is determine the minimal effective dose and the impact on: treatment outcomes at 4, 12 and/or 48 weeks the treatment has required to treat patients experiencing the first psychotic episode the final maintenance doses the use of other medications the amount of changes to other antipsychotic medication the number of hospitalization days
Extended Specialized Assertive Intervention for First Episode Psychosis
First Episode Psychosis of Schizophrenia and Schizotypal DisorderPsychotic Disorders2 moreIn a randomized clinical trial, the researchers want to investigate if the positive short-term outcomes (first 1-2 years), achieved with specialized assertive intervention programme (OPUS), can be maintained for five years if the specialized treatment is sustained over the first five years in comparison to only two years of specialized treatment followed by three years of standard treatment.
Cognitive Training to Improve Work Outcomes in Severe Mental Illness
SchizophreniaBipolar Disorder1 moreThis study will compare the efficacy of two types of supportive treatments for a program called Individual Placement and Support, which helps people with severe mental illnesses find and keep jobs.
A Clinical Trial on the Antipsychotic Properties of Cannabidiol
SchizophreniaPsychotic DisordersThe purpose of this study is to determine whether cannabidiol, a herbal cannabinoid, is effective in the treatment of acute schizophrenic or schizophreniform psychosis in a placebo-controlled, randomized double-blind study.
Medical Self-Management for Improving Health Behavior Among Individuals in Community Mental Health...
Chronic DiseaseMental IllnessThis study will evaluate the effectiveness of a medical illness self-management program in improving the health and health behavior of people who are receiving care at a community mental health center.
Treating Psychotic Symptoms of Young Individuals Presenting a First Episode of Schizophrenia: Comparison...
SchizophreniaTo verify the efficacy of a group cognitive-behavioral therapy approach to lessening psychotic symptoms of individuals with a first episode of psychosis, and to compare its effects to a known skills training approach and a control group. Our primary hypotheses were that CBT would do better than the control group at all points in time, and better than the skills training approach, though only at follow-ups
Methylphenidate for Depressed Cancer Patients Receiving Palliative Care
DepressionPalliative Care2 moreThe purpose of this study is to determine whether methylphenidate is an effective treatment for depression and to document the safety and tolerability of methylphenidate in combination with an Selective Serotonin Reuptake Inhibitor (SSRI) in SSRI treated, terminally ill, hospice and palliative care cancer patients. The investigators hypothesize that depressed hospice and palliative care patients will be more likely to have a 50% reduction in scores on a clinical measure of depression after treatment with Methylphenidate plus an SSRI compared to those patients who are taking a placebo plus an SSRI.
A Follow-up Study to Assess Safety and Tolerability of Galantamine Treatment in Individuals With...
Cognition DisorderNervous System Diseases2 moreThe purpose of this follow-up study is to assess the long-term safety and tolerability of galantamine in individuals with mild cognitive impairment who participated in a previous study with galantamine
A Study of the Efficacy and Safety of Risperidone in the Prevention of Relapse in Children and Adolescents...
Attention Deficit and Disruptive Behavior DisordersThe purpose of this study is to assess the efficacy and safety of risperidone as maintenance therapy to prevent symptoms of relapse in children and adolescents with conduct and other disruptive behavior disorders, who initially responded well to treatment.
The Effects of Different Interior Decorations in a Psychiatric Intensive Care Unit.
Mental DisordersThe purpose of the study is to compare effects of treatment of patients acutely admitted to a Psychiatric Intensive Care Unit (PICU) with either a sparsely decorated interior or interior decorations like an ordinary, Norwegian home.