Integrating Electronic Patient Reported Biometric Measures (ePReBMs) From Wearable Devices in Respiratory...
Progressive Fibrosing Interstitial Lung DiseaseLung Transplant3 moreLung diseases are one of the most common causes of emergency room visits. There are very few tools that are able to predict which patients will have a worsening or increasing severity of their condition. There are also limited ways to check the health of patients with respiratory conditions at home and during the time between medical appointments. The ADAMM-RSMTM device records heart rate, breathing rate, temperature, cough and activity while wearing it. This study will test participants willingness to wear the device and perform ongoing monitoring to assess the possibility to predict the onset and increases in severity of their lung conditions.
Postoperative Noninvasive Ventilation After Upper Abdominal Surgery in Chronic Obstructive Lung...
Acute Respiratory Failure Post Surgical (Diagnosis)In Qena university hospital a prospective, randomized study was carried out on 100 COPD patients, all were divided into; conventional therapy without NIV (C group) 50 patients or with prophylactic NIV(N group) 50 patients.NIV applied for approximately 30 to 45 min at 2- to 4-h intervals for 48 h following surgery . Primary endpoint was the acute respiratory events (ARE) .Secondary endpoints were acute respiratory failure (ARF), intubation rate, mortality rate, infectious and non-infectious complications, and ICU stay.
Frequency of Diagnostic Symptomatic Pulmonary Embolism's in Patients Hospitalized for Clinical Exacerbation...
Chronic Obstructive Pulmonary DiseasePatients Hospitalized for a COPD ExacerbationA standardized diagnostic strategy of pulmonary embolism will be applied to eligible patients, incorporating a clinical probability score (revised Geneva score), plasma D-dimer assay and if necessary, a multidetector-row CT angiography thoracic and venous ultrasound of the lower limbs. All the patient with a pulmonary embolism diagnosed or not, will be followed for 3 months.
The Effect of Reflective Breathing Therapy Compared With Conventional Breathing Therapy in Patients...
Chronic Obstructive Pulmonary DiseaseThe purpose of this study is to determine whether different types of breathing therapies in patients with COPD III-IV decrease dyspnea, increase activity and have impact on parasympathetic activities.
Prospective, Randomised Multicenter Study Comparing the Efficacy of Transbronchial Forceps Biopsy...
Interstitial Lung DiseaseThe use of cryoprobes improves the diagnostic yield in transbronchial biopsies compared to forceps biopsies to diagnose an interstitial lung disease
Fibered Confocal Fluorescence Microscopy Imaging in Patients With Diffuse Parenchymal Lung Diseases...
Diffuse Parenchymal Lung DiseasesFibered confocal fluorescence microscopy (FCFM) (CellvizioR Lung, MaunaKea Technologies, France) could potentially provide diagnostic information on fibrosis and inflammation of the distal air spaces associated with diffuse parenchymal lung diseases without the need for lung biopsies, thereby fulfilling the gap in the investigators current medical practice of a minimally invasive procedures with few complications and a high diagnostic fidelity. In patients scheduled for bronchoscopy as part of regular clinical care/diagnostic workup, the investigators will offer the patient concurrent FCFM imaging to be performed during the bronchoscopic procedure. The investigators aim to identify and catalogue distinct and discriminating features seen on images obtained from fibered confocal fluorescence microscopy in this group of patients, and to correlate these findings with specific high resolution computed tomography (HRCT) features and pathological findings if available. Eventually the investigators hope to create diagnostic criteria for fibered confocal fluorescence microscopy image interpretation of specific diffuse parenchymal lung disease entities.
Research to Evaluate a Possible Relation Between Values Obtained After Processing CT Images, Lung...
Pulmonary DiseaseChronic ObstructiveIn this study the consequences of exacerbations will be visualized by high resolution computed tomography (HRCT) scan at functional residual capacity (FRC) and total lung capacity (TLC) as taken during an episode of exacerbation and after recovering. Changes in HRCT based airway dimensions and computational fluid dynamic (CFD) -based resistance values will be correlated with changes in patient reported outcomes (PROs) and lung function tests recorded at the same time.
Trial of Vitamin D Supplementation in Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary DiseaseThe study null hypothesis is that vitamin D supplementation will not influence time to upper respiratory tract infection or time to moderate/severe exacerbation of chronic obstructive pulmonary disease.
Prophylactic Antibiotic Treatment of Patients With Chronic Obstructive Lung Disease (COLD)
Pulmonary DiseaseChronic ObstructiveThe purpose of the study is to investigate, in patients with moderate to severe chronic obstructive lung disease, whether intermittent antibiotic treatment leads to: A slower rate of decline in forced expiratory volume in one second (FEV1); A reduction in the frequency and severity of exacerbations; Fewer hospital admissions for chronic obstructive pulmonary disease (COPD); Lower mortality; An improved quality of life as compared to a group of placebo treated patients.
Human Surfactant Treatment of Respiratory Distress Syndrome Bicenter Trial
Lung DiseasesRespiratory Distress SyndromeTo determine if surfactant administration at birth in infants at high risk for respiratory distress syndrome (RDS) modified the clinical course of the syndrome.