Epidemiology of Sleep Apnea Syndrome
Lung DiseasesSleep Apnea SyndromesTo define the prevalence of Sleep Apnea Syndrome (SAS) in a community-based sample of Hispanic adults.
SCOR in Neurobiology of Sleep--Intermediate Traits for Sleep Apnea
Lung DiseasesSleep Apnea SyndromesTo determine intermediate traits for sleep apnea in a case-control study.
Endotoxin and Bronchial Inflammation in Asthma
AsthmaLung Diseases1 moreTo evaluate airway inflammation in persons with asthma exposed to endotoxin, a common occupational air contaminant. Subjects are subsequently challenged with allergen.
Sleep Apnea in a Non-Clinical Population
Lung DiseasesSleep Apnea Syndromes4 moreTo investigate the causes, consequences and quantitation of sleep disordered breathing (SDB).
Impact of Adult Asthma
AsthmaLung DiseasesTo assess the separate and interactive effects of asthma severity, subspecialty practice variation, asthma-related psychosocial variables, and other factors on asthma outcomes, including asthma-specific quality of life and activity limitations, health care utilization for asthma, and direct and indirect costs of asthma.
Sustaining Women's Smoking Cessation Postpartum
Lung DiseasesCardiovascular Diseases1 moreTo conduct a five-year demonstration and education project to sustain smoking cessation postpartum by women who had stopped smoking in pregnancy.
Tuberculosis Prophylaxis in the Homeless--A Controlled Trial
Lung DiseasesTuberculosisTo conduct a three-arm, randomized controlled trial of methods to improve adherence to biweekly directly observed prophylaxis (DOPT) for tuberculosis in homeless adults in San Francisco.
Behavioral Interventions for Control of TB
Lung DiseasesTuberculosisTo compare alternative methods to ensure completion of treatment and preventive therapy for tuberculosis (TB) in inner cities, and to identify the most cost-effective methods to accomplish that. The basis for comparison included adherence rates and cost savings as primary outcomes, and other parameters such as patient satisfaction, development of social networks, and participation in support programs as secondary outcomes. Two clinical trials were conducted with patients from Harlem. Among those with active disease, a clinic-based surrogate family model was compared to traditional community-based directly observed therapy (DOT). Among those eligible for preventive therapy, a community-based intervention conducted by trained graduates of a TB DOT program (peer workers) was compared to traditional self-administered preventive treatment.
Behavioral Interventions for Control of Tuberculosis
Lung DiseasesTuberculosisTo develop and test various educational strategies targeting primarily minority TB-infected adolescents at two health centers in Los Angeles in an experimental design to assess the relative effectiveness on medication adherence, appointment keeping, and completion of therapy.
Impact of Sleep Disordered Breathing in Older Adults
Cardiovascular DiseasesHypertension3 moreTo test the hypothesis that clinically inapparent sleep-disordered breathing was associated with blood pressure elevation, impairment of health-related quality of life, and depression.