Feasibility Study of PneumRx's Lung Volume Reduction Coil (LVRC)
EmphysemaThis is a multicenter single arm open label study. The primary objective is to evaluate the safety and effectiveness of the Lung Volume Reduction Coil (LVRC) for the treatment of patients with emphysema in multiple centers.
US 10 mL Biologic Lung Volume Reduction (BLVR) Phase 2 Emphysema Study
Pulmonary EmphysemaEvaluate the efficacy and safety of the 10 mL BLVR System in 1 or 2 treatment sessions (8 subsegments, 4 in each lung) in patients with advanced upper lobe predominant emphysema.
Bronchoscopic Thermal Vapor Ablation (BTVA) for Lung Volume Reduction
EmphysemaChronic Obstructive Pulmonary DiseaseTo assess the safety and efficacy of BTVA for the treatment of patients with heterogeneous upper lobe emphysema.
Safety and Efficacy of Arformoterol Tartrate Inhalation Solution in Subjects With Chronic Obstructive...
Chronic Obstructive Pulmonary DiseaseBronchitis1 moreTo evaluate the long-term safety and monitor the long-term efficacy of arformoterol over a period of 6 months in subjects with chronic obstructive pulmonary disease (COPD).
Efficacy of Osteopathic Manipulation in Chronic Obstructive Pulmonary Disease
EmphysemaThe purpose of this study is to determine if osteopathic manipulative treatment (OMT) is effective for persons with emphysema as a component of their chronic obstructive pulmonary disease.
Losartan Effects on Emphysema Progression
EmphysemaA randomized, parallel, placebo controlled trial to evaluate the effect of 100mg/day losartan on the progression of emphysema as measured by quantitative HRCT compared to placebo .
Evaluation of the Spiration® Valve System for Emphysema to Improve Lung Function
EmphysemaEMPROVE is a multicenter, prospective, randomized, controlled study designed to evaluate the safety and long-term effectiveness of the Spiration Valve System in patients with emphysema. Patients appropriate for the EMPROVE study are those who are currently on medical treatment but still symptomatic. EMPROVE also accepts α-1 antitrypsin deficiency patients.
Prostaglandin Inhibition for Emphysema
EmphysemaThe Prostaglandin Inhibition for Emphysema (PIE) study will determine if a currently available therapy, ibuprofen 600 mg three times daily, can block PGE production in the lower respiratory tract and if this results in improvement in measures of lung repair function.
Sequential Segmental Treatment of Emphysema With Upper Lobe Predominance (STEP-UP) Study
EmphysemaThis study is designed to demonstrate safety and efficacy in patients with severe upper lobe predominant emphysema. For validity of the study, the results will be compared to patients that receive optimal medical therapy.
Safety Study of Cell Therapy to Treat Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary DiseasePulmonary EmphysemaThe purpose of this study is to determine whether the cell therapy with bone marrow mononuclear cells is safe in the treatment of chronic obstructive pulmonary disease, specifically the pulmonary emphysema.