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Active clinical trials for "Pyelonephritis"

Results 41-50 of 81

A Study to Assess Efficacy and Safety Intravenous Benapenem in Patients With Complicated Urinary...

Complicated Urinary Tract Infection Including Acute Pyelonephritis

A Study to Assess Efficacy and Safety Intravenous Benapenem in Patients With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)

Completed56 enrollment criteria

Safety and Efficacy of ZTI-01 (IV Fosfomycin) vs Piperacillin/Tazobactam for Treatment cUTI/AP Infections...

Urinary Tract Infection SymptomaticAcute Pyelonephritis1 more

The purpose of the study is to demonstrate the safety and efficacy of ZTI-01 (IV fosfomycin) as non-inferior to piperacillin/tazobactam in overall success (clinical cure and microbiologic eradication) for the treatment of hospitalized patients with complicated urinary tract infections (cUTI) or acute pyelonephritis (AP).

Completed35 enrollment criteria

Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious...

Urinary Tract Infection ComplicatedAcute Pyelonephritis4 more

Vabomere™, (meropenem-vaborbactam) is being compared to the Best Available Therapy in the treatment of adults with selected serious infections due to Carbapenem Resistant Enterobacteriaceae

Completed48 enrollment criteria

A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection...

Complicated Urinary Tract InfectionAcute Pyelonephritis

This was a randomized, multicenter, multinational, double-blind study comparing the efficacy and safety of plazomicin compared with meropenem followed by optional oral (PO) therapy in the treatment of cUTI, including AP, in adults.

Completed13 enrollment criteria

Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With...

Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis

The purpose of this study is to evaluate the effects of Ceftazidime Avibactam compared to Doripenem for treating hospitalized patients with complicated urinary tract infections, including acute pyelonephritis

Completed9 enrollment criteria

A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Oral Ciprofloxacin in...

Urinary Tract InfectionsBacteriuria3 more

The purpose of the study is to compare the safety and effectiveness of oral levofloxacin (an antibiotic) with that of oral ciprofloxacin in the treatment of complicated urinary tract infections in adults.

Completed8 enrollment criteria

Management of Sub-Clinical Bacteriuria in Pregnancy

CystitisCystitis;Puerperium1 more

The purpose of the study is to determine if treatment of pregnant women with urine cultures with a low level of bacteria (less than 100,000 colony forming units (CFU)) may decrease adverse pregnancy outcomes.

Completed8 enrollment criteria

Pharmacokinetics of Ciprofloxacin in Pediatric Patients

Urinary Tract InfectionPyelonephritis

Measuring serum and urine concentrations of ciprofloxacin after IV and oral administration in children aged 3 months - 17 years who are treated for urinary tract infections.

Completed12 enrollment criteria

Study Comparing the Safety and Efficacy of Intravenous CXA-201 and Intravenous Levofloxacin in Complicated...

Complicated Urinary Tract InfectionPyelonephritis

This is a Phase 3, multicenter, prospective, randomized, double-blind, double dummy study of CXA 201 IV infusions (1500 mg q8h) versus levofloxacin IV infusions (750 mg qd) for the treatment of adults with a cUTI (including pyelonephritis).

Completed48 enrollment criteria

Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI...

Urinary Tract Infection ComplicatedAcute Pyelonephritis

Meropenem-vaborbactam is being compared to piperacillin-tazobactam in the treatment of adults with complicated urinary tract infection (cUTI) or acute pyelonephritis (AP).

Completed85 enrollment criteria
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