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Active clinical trials for "Gastroesophageal Reflux"

Results 121-130 of 878

A Study of Cisapride in Patients With Symptomatic Gastro-Oesophageal Reflux Disease

Gastroesophageal Reflux

The purpose of this study is to compare the efficacy and tolerability of cisapride with placebo in infants and children with gastro-oesophageal reflux disease (GORD).

Terminated6 enrollment criteria

PREA, PK And Safety PASS Study Of IV Pantoprazole In Pediatric Subjects

Gastroesophageal Reflux Disease

The purpose of this study is to characterize the pharmacokinetics (PK) and safety of intravenous (IV) pantoprazole in patients 1 to 16 years old who are candidates for acid suppression therapy.

Terminated19 enrollment criteria

A Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD)...

Gastroesophageal Reflux Disease (GERD)

The objective of this study is to evaluate the safety and efficacy of IW-3718 administered to patients with GERD who continue to have persistent symptoms, such as heartburn and regurgitation, while receiving once-daily (QD), standard-dose PPIs.

Terminated12 enrollment criteria

An Investigation of the EndoStim® Lower Esophageal Sphincter (LES) Stimulation System for the Treatment...

Gastroesophageal Reflux Disease (GERD)Reflux3 more

The purpose of this investigation is to demonstrate the safety and effectiveness of Lower Esophageal Sphincter (LES) Stimulation System in treating gastroesophageal reflux disease (GERD). This investigation is a multicenter, randomized, double-blind, sham-controlled study. After the implant procedure, subjects will be randomized to either the Treatment Group (immediate stimulation) or Control Group (delayed stimulation) for six months followed by an additional open-label phase in which all subjects will receive electrical stimulation. Subjects continue on stimulation treatment in an extended open-label follow-up phase through 5 years post-stimulation.

Terminated35 enrollment criteria

Rubber Band Ligation and Mucosectomy for Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux DiseaseHeartburn2 more

The purpose of this study is to determine the safety and effectiveness of two separate procedures to treat gastroesophageal reflux disease (GERD) also known as heartburn. The two therapies are: 1) a banding procedure alone using the Cook® 6 Shooter™ Saeed Multi-Band Ligator or 2) a banding/shaving procedure called Endoscopic Mucosal Resection (EMR) using the Cook® Duette™ Multi-Band Mucosectomy device.

Terminated8 enrollment criteria

Safety and Efficacy of Lansoprazole 30mg Twice Daily in Treatment of Laryngitis Associated With...

Laryngopharyngeal Reflux

The purpose of this study is to determine whether Lansoprazole 30mg taken twice daily is effective in the treatment of laryngitis due to gastroesophageal reflux.

Terminated24 enrollment criteria

An Evaluation of the Medtronic Gatekeeper System in the Treatment of SUBJECTS With Gastroesophageal...

Gastroesophageal Reflux Disease

The purpose of the study is to demonstrate the intended use of the Gatekeeper Reflux Repair System to provide symptomatic relief is subjects with gastroesophageal reflux disease.

Terminated12 enrollment criteria

RETHINK REFLUX Registry

Gastroesophageal Reflux

The RETHINK REFLUX Registry is a post-market prospective, multi-center, observation, single arm, long-term safety surveillance registry of subjects implanted with the LINX device. The primary objective of the study is to confirm the long-term safety profile of the LINX device and procedure (implant/explant) up to 10 years post-implant.

Active7 enrollment criteria

Car Safety Seat and Gastroesophageal Reflux Disease

Gastroesophageal Reflux Disease and Position

What's known? Prone position is no longer a treatment option for GERD because of the association with SIDS. Originally, positioning in an infant seat was recommended for infants with GERD. However, Orenstein proved this position has a detrimental effect on GER, compared to prone positioning. What's new? Positioning in an infant seat caused no increase in GER, compared with the supine 15 degrees anti-Trendelenburg position. Except for the number of long reflux episodes, which was significantly higher in the car safety seat. Larger trials are needed for decisive conclusions.

Terminated0 enrollment criteria

A Post-Approval Study of the LINX® Reflux Management System

Gastroesophageal Reflux Disease (GERD)

A Post-Approval Study of the LINX® Reflux Management System in a prospective, multicenter, single-arm study, with patients as their own control to monitor the safety and efficacy of the LINX implant procedure and device in a post-approval environment to supplement existing safety and efficacy data.

Active7 enrollment criteria
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