Adjunct Inversion for Lower Pole Stone
Kidney StoneThis is a randomized controlled trial comparing extracorporeal shockwave lithotripsy (ESWL) with and without simultaneous adjunct controlled inversion therapy in the treatment of lower pole caliceal stone.
An Analgesia Protocol for Acute Renal Colic in the Emergency Department
Kidney StoneAn analgesia protocol for acute renal colic will lead to faster significant reductions in pain than prior practice.
Study of Silodosin to Facilitate Passage of Urinary Stones
Ureteral CalculiKidney Stones1 moreThe purpose of this study is to assess if patients treated with silodosin will have a higher spontaneous passage rate of their ureteral stone than those treated with placebo.
Impact Ureteral Sheath Design During Ureteroscopy
Renal StoneNephrolithiasis1 moreThe purpose of this study is to assess whether one of two ureteral access sheaths is safer for patients undergoing ureteroscopy. Both sheaths are FDA approved devices and commercially available. The investigators will compare the ability of sheaths to access the kidney through the ureter and will compare damage done to the ureter after completion of the procedure. Access sheaths are standard of care for this procedure; this study seeks to optimize outcomes for patients. Patients undergoing ureteroscopy who do not have ureteral stents in place and who have not had an ipsilateral procedure within 90 days will be recruited and consented.
Evaluation of Pain Before and After Removal of Non-obstructive Kidney Stones
Kidney StonePain associated with renal stone disease is typically caused by an obstructing stone that obstructs the flow of urine, which results in renal collecting system dilatation. Non-obstructing renal calculi that do not cause renal collecting system dilatation are thought to be painless. The objective of this study is to prospectively determine if the removal of non-obstructing renal calculi can reduce or eliminate participant's pain and/or improve their quality of life.
Opioid Free Management After Ureteroscopy
Kidney StoneThe purpose of this research study is to compare how well two medications work to control post-operative pain.
Intraoperative Cone-beam CT for Percutaneous Nephrolithotomy
NephrolithiasisPercutaneous nephrolithotomy (PCNL) is a first-line treatment for kidney stones >2cm. Frequently, patients require multiple procedures to address their stone burden. The decision to proceed with a second-look procedure is based on follow-up CT imaging, which is obtained postoperatively. In this study, we propose the use of a portable CT scan technology to obtain follow-up imaging while the patient is still under anesthesia for the initial procedure. The goal of this study is to determine whether this allows the surgeon to identify residual fragments and render the patient stone-free within a single anesthetic event.
Indwelling Stent Discoloration Project
Urologic InjuriesDisorder of Urinary Stent3 moreThe aim of this study is to identify the root cause for the significant discolouration of Boston Scientific Percuflex based stents.
Effect of Tamsulosin on Stone Expulsion and Pain Resolution in ED Patients With Ureterolithiasis...
Kidney StoneTamsulosin (Flowmax)is approved by the FDA for the treatment for enlarged prostate. Several studies regarding the use of Tamsulosin for the treatment of lower kidney stones have been carried out in the non-Emergency Department setting. This study will compare Tamsulosin 0.4 mg with placebo in regards to rate and time of stone passing and will also look at amount of pain. The purpose of this study is to compare the usefulness of Tamsulosin versus placebo on time to stone passage and pain relief in Emergency Department patients with kidney stones.
Intravenous Ketorolac for Postoperative Pain in Percutaneous Nephrolithotomy
Renal CalculusKidney StonesThe purpose of this study is to determine whether continuous intravenous ketorolac infusion reduces pain in patients who are having percutaneous nephrolithotomy for kidney stone disease.