Blood Products in Cardiac Surgery
AnemiaRenal Impairment1 moreBlood transfusion is a common procedure essential for the treatment of patients undergoing cardiac surgery. Inappropriate transfusions, however, not only incur needless healthcare costs, but increase unnecessary risks due to transfusion reactions and infectious and immunomodulative causes. Safe and appropriate patient care requires evaluated blood component prescription practices. Practically all patients undergoing cardiac surgery in Finland have a blood product booking from the Finnish Red Cross Blood Service. This registry contains large volumes of transfusion-related information on all Finnish patients undergoing cardiac surgery in Finnish centers. Participating hospitals were scattered to all geographical areas in Finland and concentrated to the most populated regions. Data on the blood product use, laboratory findings one month pre-operatively and 12 months post-operatively were available. Finnish hospitals have been required to provide information on hospital visits for the Finnish National Research and Development Centre for Welfare and Health for healthcare planning purposes. We used in part the original data sent by hospitals to the Finnish Hospital Discharge Register (FHDR).
Pilot Study of Contrast-Enhanced Ultrasound of Transplanted Kidney
Transplant; FailureKidneyTo check the possibility of the acquisition of a number of parameters through real-time contrast-enhanced ultrasound and sonoelastography images and to verify the correlation with pathologic results from ultrasound guided biopsy of transplanted kidney
Insulin Dosing in Diabetic Patients With End Stage Renal Disease (ESRD) or Hemodialysis
DiabetesHypoglycemia2 moreThe purpose of this study is to assess whether the current recommendation for a 50% dose reduction in insulin for diabetic patients with a creatinine clearance (CrCl) ≤15 mL/min or on hemodialysis results in an increased number of hypoglycemic episodes.
Hemodialysis and Wanting for Protein-rich Foods
Renal FailureA study conducted in the laboratory revealed the existence of a "window" during which patients with renal failure appreciate the protein-rich foods. This period, located immediately after the dialysis, is likely related to the purification of plasma products resulting from protein catabolism. It therefore appears necessary to understand the mechanisms that may explain these changes by measurements of ghrelin (orexigenic hormone), leptin (anorectic hormone) and plasma amino acids.
AKIN Criteria: Acute Kidney Injury After On-Pump Coronary Artery Bypass Graft (CABG)
Kidney FailureThe purpose of this study is evaluate clinical outcomes and 30-day mortality after on-pump CABG.
Impact of Early Renal Involvement on the Development of Severe In-hospital Renal Failure
Kidney FailureAcute4 moreThe purpose of this study is to determine whether renal team involvement early at the onset of kidney injury will prevent further developement of more severe renal failure and worse hospitalization outcomes.
New Non-invasive Methods for Real-time Monitoring of Organ Function.
Acute Renal FailureChronic Renal FailureMeasuring novel proteins in the urine of surgical patients that can be used to diagnose impending acute or chronic renal failure.
Erythropoietin Resistance in Anemia of Chronic Kidney Disease
AnemiaKidney Failure1 moreOur goal of this pilot project is to identify inflammatory biomarkers that correlate with epo-resistance among CKD patients.
A Study of Cytokine and Inflammatory Markers in Patients With Chronic Renal Failure
Chronic Renal FailureWe hope to study components within the blood that may predict success, failure or other associated complications in relation to the type of vascular access being used.
Hemodynamic Assessment APCO Monitor vs Crit Line for Renal Replacement Rx
Renal FailureHemodynamicsFluid and volume management are a challenging part of critical care and the difficulties increase in the face of renal failure. Utilizing the Crit-Line to monitor blood volume changes in conjunction with arterial pressure cardiac output monitoring may lead to better understanding of the impact fluid removal during dialysis has on hemodynamics.