Study of the Causes of the Breakdown of Muscle Fibers in Hospitalized Patients
RhabdomyolysisMyopathy2 moreAnalyze the various causes of breakdown of muscle fibers in hospitalized patients. Analyze the characteristics of these patients in Taiwan (including the drugs history, risk factors and the incidence of complications).
Development of a Biomarker Panel for the Earlier Prediction of Acute Kidney Injury in Patients With...
Diabetes MellitusRenal ImpairmentPatients living with diabetes mellitus have double the risk of kidney failure compared to patients without diabetes following use of dye in many x-rays and procedures to diagnose and treat narrowing of the arteries (blood vessels) in the heart that can lead to angina or a heart attack. Heart disease is the commonest cause of death in patients with diabetes. People with diabetes are more likely to need these tests/treatments. By identifying those at greater risk of kidney complications we may be able to make these tests/treatments safer and offer them to more patients with diabetes.
Urinary Marker for Oxidative Stress in Human Cisplatin- Induced Renal Injury
Kidney FailureWe previously reported early measurement of urinary MDA might be a useful marker for the prediction of CDDP-induced renal damage in rat. The purpose of this clinical study is to test whether the changes of human urinary excretion of MDA, and can be used as early biomarker for the prediction of development of CDDP-induced ARF.
Vitamin Metabolism in Kidney Disease
Kidney FailureThe purpose of this study is to evaluate the urinary excretion and renal metabolism of vitamins, in particular vitamin B12 and folate, in relation to various renal conditions involving loss of renal function and/or proteinuria.
The Lolland-Falster Health Study
Impaired HealthDisease13 moreThe study is a epidemiological, cross-sectional study in a mainly rural area of Denmark in Denmark. Life expectancy is shorter, morbidity is higher, and social problems more prevalent than in the urban areas of the country. The population study aims at examining complexities of environmental, hereditary, lifestyle, and social factors as determinants and predisposing factors for morbidity, health, and quality of life. The study will cover physical, mental, and social dimensions and examine family patterns and subgroups. The study will provide baseline information for later follow-up.
Prospective Study of Urinary Markers of Fibrosis in Kidney Transplants
Kidney FailureThe purpose of this study is to determine whether urinary connective tissue growth factor (uCTGF) can predict the onset of fibrosis in transplanted kidneys.
Risk Assessment of Peritoneal Dialysis Failure Based on Catheter Tip Location.
Renal FailureThe location of the catheter tip in radiographic planes 1 and 2, is a protection factor for the mechanical performance of peritoneal Dialysis. Instead radiographic planes 3 and 4 are risk factors.
Pharmacokinetics of Meropenem During High-dose CRRT
InfectionRenal FailureAssessment of meropenem plasma concentration in critically ill patients who require CRRT (continuous renal replacement therapy). A standard dose of meropenem is administered, i.e. 1 gram every 8 hours.
Venous Congestion and Acute Renal Failure in Cardiac Surgery Postoperative
Acute Renal Failure (ARF)Acute renal failure (ARF) is a frequent complication in the postoperative cardiac surgery, and is a major risk factor for mortality in this context. The right ventricular dysfunction post cardiopulmonary bypass (CPB) is also a common complication, close to 100% if one takes into account the transient dysfunction. A recent study showed that right ventricular dysfunction and the IRA seemed related, rather on the slope of venous congestion. We wish to study this phenomenon more specifically in particular to offer reliable diagnostic markers of venous congestion.
Postoperative Renal Failure in Cardiac Surgery PMSF-PVC Gradient Study
Scheduled Heart SurgeryValve Replacement1 moreAcute renal failure is a frequent and severe postoperative complication of cardiac surgery performed under extracorporeal circulation. It is an independent risk factor for mortality and significantly increases the length of hospital stay. The origin of renal insufficiency after extracorporeal circulation is multifactorial (long duration of extracorporeal circulation, hemodynamic instability per and post-extracorporeal circulation, prolonged hypotension, transfusion ...). Nevertheless, an entirely different pathophysiological mechanism, though not recent, is less often mentioned but shows renewed interest. This is the concept of renal venous congestion which may be responsible for impaired renal function in the absence of cardiac dysfunction. Based on Guyton's circulatory model, the investigators approach this systemic venous hypertension through the measurement of the Pmsf-PVC gradient.