Development of a New Tool for Dyspnea Measurement in Chronic Respiratory Diseases
COPD (With - Without Rehabilitation)Diffuse Interstitial Lung Diseases2 moreThe purpose of this study is the psychometric validation of a self-administered dyspnea questionnaire, usable in clinical practice in order to assess dyspnea and its impact on patients with chronic respiratory diseases.
Study to Evaluate the Human Infection of the Lower Respiratory Tract in Children at High Risk
Severe Respiratory Disease- Estimate the incidence rate of hMPV infection detected by RT-PCR from frozen nasal wash aspirates in children at high risk for severe LRI disease (hospitalized at <2 years of age).
Use of Lung Ultrasound to Diagnose the Etiology of Respiratory Failure in a PICU.
Pediatric Respiratory DiseasesRespiratory FailureThe purpose of this study is to determine the utility of point-of-care lung ultrasound (POC-LUS) in identifying the etiology of acute respiratory failure in pediatric patients admitted to the pediatric intensive care unit.
Characteristics of Patients Diagnosed With NSAID Sensitivity in Thailand
Aspirin SensitivityAspirin-exacerbated Respiratory Disease6 moreStudy clinical characteristics and phenotypes of patients diagnosed with NSAID sensitivity in Thailand
Within-Breath Total Respiratory Input Impedance in Healthy Adult Subjects
Respiratory DiseaseAssessment of lung function requires the evaluation of pulmonary function by spirometry. However, some patients (e.g. children, elderly, or diseased individuals) may have difficulty performing the related forced maximal respiratory maneuver correctly. Forced oscillation technique (FOT) is increasingly being used in clinical settings to evaluate lung function noninvasively by measuring the mechanical input impedance of the respiratory system. FOT measures lung impedance during tidal breathing, requiring minimal patient cooperation. Recently a new methodology (within breath analysis) has emerged to evaluate changes that occur in the impedance during the breathing activity. The within-breath calculation of impedance allows separating the contribution of inspiration and expiration to the measured parameters. The purpose of this study is to establish reference ranges for within breath FOT parameters and their short term variability.
Diagnostic Accuracy Of Forced Oscillation Technique To Detect Lung Function Anomalies
Respiratory DiseaseThe diagnosis of a lung function anomaly requires the evaluation of pulmonary function by spirometry. However, some patients (e.g. children, elderly, or diseased individuals) may have difficulty performing the related forced maximal respiratory maneuver correctly. Forced Oscillation Technique (FOT) measures lung impedance during tidal breathing, requiring minimal patient cooperation. The purpose of this study is to establish the diagnostic accuracy of FOT parameters alone or in combination with lung volumes in detecting lung function anomalies as compared with spirometry and with the diagnosis made by the physician.
Cardiorespiratory Diagnostic Study
COPDAsthma8 moreThis study uses a new breathing device called 'N-Tidal C' handset which measures breathing patterns. Investigators have found that people with cardiac and respiratory illnesses breathe out a gas, called carbon dioxide (CO2), in a different way to healthy people. The pattern of breathed out CO2 (the waveform) varies according to the underlying health of the user's lungs. Monitoring these changes may help doctors to more accurately diagnose and monitor the most common and serious respiratory conditions.
Artificial Intelligence in Diagnosing Dysphagia Patients
Respiration DisordersSwallowing Disorder4 moreIn this prospective study we extracted acoustic parameters using PRAAT from patient's attempt to phonate during the clinical evaluation using a digital smart device. From these parameters we attempted (1) to define which of the PRAAT acoustic features best help to discriminate patients with dysphagia (2) to develop algorithms using sophisticated ML techniques that best classify those i) with dysphagia and those ii ) at high risk of respiratory complications due to poor cough force.
Research on the Application and Mechanism of New Biological Probes in Biomedicine
TumorsCardiovascular Diseases9 moreFluorescence is one of the most commonly used research and detection techniques in the field of biomedical science. The characteristics of fluorescent probe directly affect the performance and application of fluorescence analysis and imaging. Aggregation-Caused Quenching has limited the application of traditional fluorescent probes to some extent. This project intends to systematically evaluate the detection efficiency of new methods through the detection of biomarkers in clinical samples and the comparison with the detection methods of traditional biomarkers, so as to provide theoretical and experimental basis for the establishment of fast and simple biomarker detection technologies with new biological probes.
The Corona Study of Middle Norway
SARS-CoV-2 Acute Respiratory DiseaseSARS-CoV-2 Sepsis1 moreCUT COVID is a cohort study establised to collect information on patients hospitalized because or with infection by SARS-CoV-2. The cohort data includes clinical data and biological samples from multiple timepoints during hospitalization, as well as data from a followup consultation 3 months after discharge.