ALX-0171 Phase I Study, Evaluating Single Ascending Dose and Multiple Dose in Healthy Male Volunteers...
RSV InfectionALX-0171 is a Nanobody directed against the human respiratory syncytial virus (RSV). The purpose of this first-in-man study is to determine the safety, tolerability and pharmacokinetics (PK) of ALX-0171 after single and multiple pulmonary administrations in healthy male volunteers.
Phase 2b Study of ALN-RSV01 in Lung Transplant Patients Infected With Respiratory Syncytial Virus...
Respiratory Syncytial Virus InfectionsTo evaluate the efficacy and safety of ALN-RSV01 plus standard of care in RSV infected lung transplant patients
A Study of AK0529 in Chinese Infants Hospitalized With RSV
Respiratory Syncytial Virus InfectionsThis is a randomized, double-blind, placebo-controlled, multicenter, phase III study to be conducted in infants hospitalized with RSV infection in China. The main objectives of this study are to investigate the efficacy and safety of AK0529 in Chinese infants.
Drug Interaction Study With RV521 in Healthy Volunteer Subjects
Respiratory Syncytial Virus InfectionsThe main aim of this study is to determine whether RV521 interacts with any other medication using four licensed medicines (midazolam, itraconazole, rifampicin and verapamil) that are known to have specific effects on enzymes and transporter proteins that influence the absorption of drugs
Drug-Drug Interaction Study Between Fluconazole and EDP-938 in Healthy Subjects
RSV InfectionA Non-Randomized, Open-Label, Drug-Drug Interaction Study to Evaluate the Effects of Fluconazole on the Pharmacokinetics and Safety of EDP-938 in Healthy Subjects
RV568 - Viral Challenge With RSV
Respiratory Syncytial Virus InfectionsRV568 is being developed for the treatment of diseases such as asthma, COPD and allergic rhinitis (e.g. hayfever). The main aim of this study is to investigate whether RV568 is effective in reducing the inflammation caused by viral infections such as RSV (respiratory syncytial virus).
Safety Study of Oral BTA9881 to Treat RSV Infection
Respiratory Syncytial Virus InfectionsThis is a placebo-controlled, double-blind, randomised, single dose escalation Phase I clinical trial to determine the safety and tolerability of BTA9881 administered orally to healthy subjects
Study of Single and Multiple Doses of ALS-008176 in Healthy Volunteers
Respiratory Syncytial Virus InfectionsThis study will assess the safety, tolerability, and pharmacokinetics (PK) of orally administered ALS-008176 in healthy volunteers.
Study to Evaluate Antiviral Activity, Safety, and Pharmacokinetics of Repeated Doses of Orally Administered...
Respiratory Syncytial Virus InfectionsThe purpose of this study is to evaluate the antiviral effect of repeated oral dosing of JNJ 53718678 compared to placebo in healthy adult participants infected through inoculation with respiratory syncytial virus (RSV)-A Memphis 37b virus.
A Multicentre Study in Otherwise Healthy Infants and Toddlers Hospitalised For and Diagnosed With...
Respiratory Syncytial Virus InfectionThe primary objective of the study is to investigate the safety and tolerability of ALX-0171. The secondary objectives are to evaluate the clinical effect of ALX-0171 and to explore the pharmacodynamics (PD) and the systemic pharmacokinetics (PK) of ALX-0171.