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Active clinical trials for "Retinal Perforations"

Results 61-70 of 128

Partial Posterior Hyaloidectomy in Macular Surgery

Retinal BreakRetinal Detachment

To evaluate the effect of partial posterior hyaloidectomy on preventing iatrogenic retinal breaks related to induction of a posterior vitreous detachment

Completed2 enrollment criteria

Efficacy of Exercise Program for Facedown Posture-related Pain After Retinal Surgery

Macular HolesRetinal Detachment

The purpose of this study is to evaluate the effects of a structured exercise program on musculoskeletal pain of patients in face-down posture after retinal surgery.

Completed4 enrollment criteria

Association of Lutein, Zeaxanthin and Brilliant Blue in Chromovitrectomy

Epiretinal MembraneMacular Hole1 more

The aim of this study is to test the efficacy of the combination of dye Lutein, Zeaxanthin and brilliant blue to stain the internal limiting membrane as well as the epiretinal membranes during the Vitrectomy surgery.

Completed6 enrollment criteria

Macular Hole Surgery With Temporal Inverted Internal Limiting Membrane Flap (MARTIAL)

Macula Hole

Since 1991, idiopathic macular holes (MH) can benefit from an effective treatment initially involving pars plana vitrectomy, stripping of epiretinal membranes and intraocular gas tamponade followed by facedown positioning. The initial 58% success rate has further increased to 85-100% with internal limiting membrane (ILM) peeling. However, complete ILM removal has been shown to lead to anatomic changes causing the retina to have the appearance of a dissociated optic nerve fiber layer (DONFL). Moreover, it has been associated with decreased retinal sensitivity that may cause visual discomfort despite good visual acuity. Nawrocki et al. recently suggested to reduce the area of peeled ILM (temporal inverted ILM flap technique) in order to minimize iatrogenic trauma while maintaining satisfactory surgical outcomes. The aim of this study is to compare the incidence of DONFL appearance and retinal sensitivity after macular hole surgery in eyes that underwent temporal inverted ILM flap technique and eyes that had complete ILM peeling

Unknown status5 enrollment criteria

MSC-Exos Promote Healing of MHs

Macular Holes

Purpose: To assess the safety and efficacy of mesenchymal stem cells (MSCs) and MSC-derived exosomes (MSC-Exos) for promoting healing of large and refractory macular holes (MHs). Hypothesis: MSC and MSC-Exo therapy may promote functional and anatomic recovery from MH. MSC-Exo therapy may be a useful and safe method for improving visual outcomes of surgery for refractory MHs.

Unknown status14 enrollment criteria

Pars Plana Vitrectomy With 25-gauge 20000 Cpm, Bevel-tip Cutter

VitrectomyRetinal Detachment5 more

Report efficiency and clinical outcomes using 25-gauge, bevel-tip, 20000 cut per minute vitrectomy probe among eyes with various vitreo-retinal diseases

Unknown status2 enrollment criteria

Clinical Research on the Effect of Different Extents of Internal Limiting Membrane Peeling on Macular...

Macular Holes

Observing and describing the surgical effects of different extents of internal limiting membrane peeling combined with internal limiting membrane insertion for macular hole

Unknown status9 enrollment criteria

A Study of a New Surgical Treatment of Macular Hole Retinal Detachment in High Myopia

Macular HolesRetinal Detachment1 more

This study evaluates the surgical outcomes of inverted internal limiting membrane insertion combined with air tamponade in the treatment of macular hole retinal detachment (MHRD) in high myopia, and also to compare the treatment efficacy and safety between different surgical approaches of MHRD

Unknown status23 enrollment criteria

The Intravitreal Autologous Platelet Concentrate Injection as an Adjunct of Vitrectomy for the Treatment...

Macular Hole With High Myopia (Spherical Equivalent ≤ -6.0 Diopters) or,Large Size Macular Hole (Diameter > 600 Microns) or2 more

The purpose of this study is to determine the effectiveness of intravitreal autologous platelet concentrate (APC) injection during the surgery for refractory macular holes.

Unknown status8 enrollment criteria

Comparative Analysis of Large Macular Hole Surgeries

Macular Holes

This study compares the anatomical and visual outcomes in a large series of patients affected by idiopathic macular holes larger than 400 µm treated using pars plana vitrectomy and gas tamponade combined with internal limiting membrane (ILM) peeling or the inverted internal limiting membrane flap technique. A part of the participants will receive internal limiting membrane peeling,whil the other will receive the inverted internal limiting membrane flap technique.

Unknown status2 enrollment criteria
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