Biomarkers in Patients With Advanced Rhabdomyosarcoma
Adult RhabdomyosarcomaChildhood Alveolar Rhabdomyosarcoma6 moreThis research trial studies tumor tissue to identify important proteins and biomarkers from patients with rhabdomyosarcoma that has spread to other places in the body and usually cannot be cured or controlled with treatment. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors identify biomarkers related to cancer.
Biomarkers in Tumor Tissue Samples From Younger Patients With Rhabdomyosarcoma
Alveolar Childhood RhabdomyosarcomaChildhood Rhabdomyosarcoma1 moreThis research trial studies biomarkers in tumor tissue samples from younger patients with rhabdomyosarcoma. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer
Retrospective Study in FFPE Samples From Younger Patients With Rhabdomyosarcoma
Alveolar Childhood RhabdomyosarcomaEmbryonal Childhood Rhabdomyosarcoma1 moreThis retrospective study is looking into mechanisms of drug therapy resistance in FFPE samples in recurrent and refractory Rhabdomyosarcoma (RMS) in pediatric patients who have experienced lung recurrence. The study employs advanced techniques such as single-cell transcriptomics and spatial transcriptomics to gain a comprehensive understanding of these mechanisms.
Studying Protein Expression in Tissue Samples From Younger Patients With Rhabdomyosarcoma
Alveolar Childhood RhabdomyosarcomaEmbryonal Childhood Rhabdomyosarcoma3 moreThis research trial studies protein expression in tissue samples from younger patients with rhabdomyosarcoma. Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors find better ways to treat cancer.
Collecting Tumor Samples From Patients With Gynecological Tumors
Borderline Ovarian Clear Cell TumorBorderline Ovarian Serous Tumor85 moreThis laboratory study is collecting tumor tissue and blood samples from patients with gynecologic tumors. Collecting and storing samples of tumor tissue and blood from patients with cancer to study in the laboratory may help in the study of cancer.
Elucidating the Genetic Basis of the Pleuropulmonary Blastoma (PPB) Familial Cancer Syndrome
Pleuropulmonary BlastomaCystic Nephroma8 morePleuropulmonary Blastoma (PPB) is a rare lung tumor which develops in childhood. The underlying genetic factors which contribute to the development and progression of PPB are not defined. We are working to identify the genetic factors which may contribute to the development of this rare tumor.