
A Study in Pregnant Women With Chronic Inflammatory Diseases Treated With Cimzia (Certolizumab Pegol)...
Rheumatoid ArthritisPsoriatic Arthritis3 moreThe purpose of the study is to assess systemic certolizumab pegol (CZP) exposure, the formation of anti-CZP antibodies and safety of CZP across the course of pregnancy in study participants with chronic inflammatory diseases.

A Study of Human Substance Balance and Biotransformation of [14C]SHR0302
Rheumatoid Arthritis (RA)The study is being conducted to evaluate the absorption, metabolism and excretion of [14C]SHR0302 in healthy Chinese adult male subjects.

Effects of a Mobile Application RA Joint Protection and Activity Self-management Program
ArthritisRheumatoidThe goal of this clinical trial is to evaluate the effectiveness of mobile application self-management program (App) for joint protection and physical activity in patients with rheumatoid arthritis. Intervention group received an app self-management program. The researchers compared the effects of the experimental group and the control group in disease activity, physical functioning, self-efficacy, depression, and self-management behavior.

Study to Assess Changes in the Immune Profile in Adults With Early Rheumatoid Arthritis
Rheumatoid ArthritisThe purpose of this study is to examine changes in immune cells and proteins in response to treatment with two approved therapies for Rheumatoid arthritis (RA), abatacept versus adalimumab, both given in combination with methotrexate.

Fibrocytes in Rheumatoid Arthritis, Asthma and Interstitial Lung-disease.
Interstitial Lung DiseasesRheumatoid Arthritis1 moreTo study Fibrocytes in patients with Rheumatoid Arthritis, Interstitial lung disease and severe asthma and healthy controls.

Single-dose Study to Describe the Pharmacodynamics (PD) and Safety of Sarilumab (REGN88/SAR153191)...
Rheumatoid ArthritisThe main purposes of this study are to describe the pharmacodynamic effects, safety and pharmacokinetics of a single dose of sarilumab.

Sarilumab Effect on the Pharmacokinetics of Simvastatin
Rheumatoid ArthritisPrimary Objective: To evaluate the effect of a single 200 mg subcutaneous injection of sarilumab on the pharmacokinetics of simvastatin in patients with rheumatoid arthritis Secondary Objective: To describe the safety and efficacy (exploratory) of sarilumab

Lifestyle Interventions Based on the Mediterranean Diet for Patients With Rheumatoid Arthritis
Rheumatoid ArthritisAim of the present study was to evaluate the effect of different lifestyle intervention administrations, in increasing adherence to the Mediterranean diet in a group of patients with RA living in the Mediterranean basin, and, thus, in improving parameters related to subjective and objective disease markers, including plasma adiponectin concentrations.

Effects of Administration of Fostamatinib on Blood Concentrations of Rifampicin in Healthy Subjects....
Rheumatoid ArthritisHealthy VolunteersThe purpose of this study is to investigate the drug interaction between fostamatinib and rifampicin by comparing the safety, tolerability and plasma concentration of fostamatinib when administered alone and with rifampicin in healthy subjects

Effects of Administration of Fostamatinib on Blood Concentrations of Warfarin in Healthy Subjects...
Rheumatoid ArthritisHealthy SubjectsThe purpose of this study is to determine whether fostamatinib influences the plasma concentration of warfarin and changes its blood thinning effect, and to investigate how safe and tolerable it is when administered with warfarin.