search

Active clinical trials for "Subarachnoid Hemorrhage"

Results 401-406 of 406

Prognostic Value of Circulating Endothelial Progenitor Cells in Aneurysmal Subarachnoid Hemorrhage...

Aneurysmal Subarachnoid Hemorrhage

Aneurysmal subarachnoid hemorrhage is a common and serious disease associated to a high rate of mortality and morbidity. Severe definitive neurological impairment can concern up to 30% of patients in relation with elevated intracranial pressure, hemorrhage recurrence and symptomatic cerebral arterial vasospasm. This latter complication is defined as a reversible reduction of cerebral artery's diameter occurring between the 4th and the 14th day after bleeding. Physiopathology is not well understood, but could involve endothelium, trough endothelial progenitor cells (EPC). Circulating EPC are bone marrow-derived cells with capacity of vasculogenesis and angiogenesis. EPC have been recognized playing a beneficial role in cardiovascular disease and ischemic stroke. EPC have never been studied in aneurysmal subarachnoid hemorrhage. The primary objective of this study is to compare the number of circulating endothelial progenitor cells between patients with a good neurological outcome (defined as a glasgow outcome scale = 1 or 2) and patients with a poor neurological outcome (glasgow outcome scale = 3, 4 or 5). Briefly, the number of circulating EPC will be measured at admission, and at day 3, 6, 10, 14, 21 in each consecutive patient suffering aneurysmal subarachnoid hemorrhage and hospitalized in Teaching Hospital of Besançon (France). The neurological outcome will be measured one year after subarachnoid hemorrhage.

Unknown status8 enrollment criteria

Pituitary Dysfunction After Aneurysmal Subarachnoid Hemorrhage

Thyroid DisfunctionSubarachnoid Haemorrhage From Cerebral Aneurism Rupture1 more

Recently, the occurrence and potential impact of pituitary dysfunction after aSAH has gained increasing interest. Several studies have demonstrated pituitary dysfunction after SAH suggesting that pituitary dysfunction may be a contributing factor for residual symptoms after SAH. This is an observational multicentric study aimed to test the prevalence of thyroid abnormalities, other neuroendocrinological dysfunction and their influence on outcome of patients affected by aSAH.

Unknown status2 enrollment criteria

Incidence and Effects of Sleep Apnea on Intracerebral Aneurysms

Sleep Apnea (Defined as Apnea Hypopnea Index > 5/h)Intracranial Aneurysm Size3 more

Patients with intracerebral aneurysm will be screened for sleep apnea using out of center polysomnography/polygraphy. Baseline blood pressure and medication will be assessed. Patients will be followed for up to 5 years to examine the increase in aneurysm size, rupture rate and changes in medication.

Unknown status4 enrollment criteria

Observational Study of Patients With Subarachnoid Hemorrhage

Subarachnoid Hemorrhage

This prospective, observational study aim to identify : Prognostic factor of patients with subarachnoid haemorrhage in neuro intensive care unit The impact of standard therapeutic used (surgery, embolization ; medical treatment of vasospasm ; treatment of complications like hyponatremia, stress myocardiopathy, …)

Unknown status2 enrollment criteria

Effect of Sleep Apnea on Blood Pressure Control and Outcome Early After Subarachnoid Hemorrhage...

Subarachnoid HemorrhageSleep Apnea

In this observational study patients with subarachnoid hemorrhage (SAH) will be screened for sleep apnea (SA) to investigate if SA is associated with impaired blood pressure control and worse clinical outcome early after SAH.

Unknown status6 enrollment criteria

Heart Rate and Initial Presentation of Cardiovascular Diseases (Caliber)

Abdominal Aortic AneurysmCoronary Heart Disease NOS13 more

Study of heterogeneity in associations between heart rate and the initial presentation of 12 cardiovascular diseases.

Unknown status4 enrollment criteria
1...4041

Need Help? Contact our team!


We'll reach out to this number within 24 hrs