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Active clinical trials for "Cicatrix, Hypertrophic"

Results 61-70 of 88

The Safety and Efficacy of Thermo-mechanical System for Fractional Ablation Associated Triamcinolone...

Keloid

This study aims to assess the safety and efficacy of Thermo-mechanical system for fractional ablation associated triamcinolone acetonide drug delivery for the treatment of Hypertrophic scars and Keloids.

Unknown status7 enrollment criteria

Effect of Cryotherpy on Hypertrophic Scar

Hypertrophic Scars

Purpose of the study: The purpose of the study is to evaluate the therapeutic effect of cryotherpy in treating hypertrophic scar. It will be hypothesized that: Cryotherapy may not have an effect on hypertrophic scar.

Unknown status9 enrollment criteria

Regenerative Effects of Human Stem Cell Media After Laser Therapy in Hypertrophic Scar

Stem Cell MediaHypertrophic Scar1 more

The purpose of this study was to determine the effect of combined treatment using nonablative laser and human stem cell media (HSCM) on the regeneration of hypertrophic scars that occurred after burns.

Unknown status7 enrollment criteria

Effectiveness of a Combined Pressure and Silicone Intervention for Hypertrophic Scar Treatment

CicatrixHypertrophic1 more

Pressure therapy (PT) and silicone therapy are recommended as first-line non-invasive treatments HS, yet the effectiveness of the combination of these two treatments through an RCT trial has not been established yet. This study aims to examine the effectiveness of the combination of adequate pressure therapy and silicone gel sheeting implemented by Smart Scar Care Pad (SSCP) + Smart Pressure Monitored Suit (SPMS) versus conventional Pressure Garment (PG in the management of severe HS in adult. It is hypothesized that the combination of adequate pressure therapy and silicone gel sheeting will demonstrate its superiority in improving scar parameters than conventional pressure garment therapy.

Unknown status7 enrollment criteria

A Substantial Equivalence Study of RD04723 and Predicate Device

Hypertrophic ScarKeloid Scar

The purpose of this study is to determine whether a developmental formulation is substantially equivalent to the predicate device in the treatment of hypertrophic and keloid scars.

Unknown status11 enrollment criteria

A Study to Evaluate the Effectiveness and Safety of RXI 109 on the Outcome of Revised Hypertrophic...

Hypertrophic Scar

The purpose of this study is to determine the effectiveness of RXI-109 in reducing the recurrence of hypertrophic scar formation following elective revision of a pre-existing hypertrophic scar.

Unknown status6 enrollment criteria

The Use of Botulinum Toxin in the Treatment of Itching From Hypertrophic Scar -- A Randomised Controlled...

ItchinessHypertrophic Scar1 more

Hypertrophic scar, a disfiguring tissue reaction to trauma, occurred in around 20 % of the population. The patients with hypertrophic scar usually seek medical assistance not just for the annoying appearance but mostly due to the intractable itchiness. There have been a variety of effective methods to alter the appearance of the scar. However, the treatments for itching from hypertrophic scar are scarce. In 2009, P.Gazerani used Botox to treat histamine-induced itch with favorable results. In the clinical setting, however, the efficacy of Botox to treat itch from hypertrophic scar was yet to be proven. Therefore, the goal of this study is to conduct a randomized controlled trials about using Botox to treat itch from hypertrophic scar.

Unknown status7 enrollment criteria

Treatment of Hypertrophic Scars With Intradermal Botox

Hypertrophic Scar

This is a prospective, open label, single center, self-controlled clinical study to demonstrate the safety and efficacy of intradermal botulinum toxin in treating hypertrophic scarring.

Unknown status18 enrollment criteria

Fractional Microneedling RF vs Intralesional Steroid With & Without Microneedling in Hypertrophic...

Hypertrophic Scars

Comparing between the effect of Fractional Microneedling Radiofrequency Versus Intralesional Steroid Injection with and without Microneedling on Tissue levels of PDGF & CTGF in Hypertrophic Scars

Unknown status11 enrollment criteria

Botulinum Toxins Intralesional Injection for Scar Pain

Scar KeloidHypertrophic Scar

Botulinum toxins has been approved by the FDA to treat chronic migraine. Botox had been shown to inhibiting the release of inflammatory mediators and peripheral neurotransmitters from sensory nerve to treat neuropathic pain. In the clinical practice, botox indeed effect in scar pain. However, investigators need well controlled study to prove this finding and assess the improvement of scar appearance.

Unknown status7 enrollment criteria
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