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Active clinical trials for "Alzheimer Disease"

Results 861-870 of 2939

Phase 3 IGIV, 10% in Alzheimer´s Disease

Alzheimer´s Disease

The purpose of this study is to provide evidence of efficacy and safety to support the development of IGIV, 10% as a treatment option for patients with mild to moderate Alzheimer´s Disease.

Terminated51 enrollment criteria

Study to Evaluate the Preliminary Safety, Efficacy, PK and PD of Bryostatin 1 in Patients With Alzheimer's...

Alzheimer's Disease

This study is being done to evaluate the safety, tolerability and potential effectiveness of a new investigational drug, bryostatin 1, in patients with Alzheimer's disease (AD).

Terminated26 enrollment criteria

Study of the Pharmacokinetics and Pharmacodynamics of POSIPHEN® in Subjects With Amnestic Mild Cognitive...

Alzheimer's DiseaseAmnestic Mild Cognitive Impairment

This trial will determine the pharmacokinetics of Posiphen® in both plasma and CSF after a 10-day treatment period with Posiphen® in subjects with amnestic MCI. The effects of this treatment on biomarkers will also be determined in CSF, whole blood, and plasma or serum as primary pharmacodynamic (PD) objectives.

Terminated24 enrollment criteria

A Long-Term Safety And Tolerability Study Of Bapineuzumab In Alzheimer Disease Patients

Alzheimer Disease

The purpose of this study is to assess the long-term safety and tolerability of bapineuzumab in subjects with Alzheimer Disease who participated in study 3133K1-3000 (NCT00667810). Over 250 sites will participate in over 26 countries. Subjects will receive bapineuzumab. Each subject's participation will last approximately 4 years.

Terminated6 enrollment criteria

A Long-Term Safety And Tolerability Extension Study Of Bapineuzumab In Alzheimer Disease Patients...

Alzheimer Disease

The purpose of this study is to assess the long-term safety and tolerability of bapineuzumab in subjects with Alzheimer Disease who participated in study 3133K1-3001(NCT00676143). Over 250 sites will participate in over 26 countries. Subjects will receive bapineuzumab. Each subject's participation will last approximately 4 years.

Terminated6 enrollment criteria

A Long-Term Safety and Tolerability Study in Subjects With Mild to Moderate Alzheimer's Disease...

Alzheimer's Disease

The purpose of this study is to assess the long-term safety and tolerability of Bapineuzumab (AAB-001, ELN115727) in subjects with Alzheimer's disease who participated in study ELN115727-301 or study ELN115727-302.

Terminated7 enrollment criteria

Study of Combination Therapy With Dimebon and Donepezil (Aricept) in Patients With Alzheimer's Disease...

Alzheimer's Disease

The purpose of this study is to assess the safety and efficacy of Dimebon in combination with donepezil (Aricept) in the treatment of Alzheimer's disease.

Terminated5 enrollment criteria

Safety and Efficacy Study of ABT-089 in Adults With Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

The purpose of this study is to test if the investigational medication ABT-089 is a safe and effective treatment for Alzheimer's disease.

Terminated10 enrollment criteria

Effect on Cognitive Performance and Safety/Tolerability of SSR180711C in Mild Alzheimer's Disease...

Alzheimer's Disease

The primary objective of the study is to assess the effect of 3 doses of SSR180711C on cognitive performance in patients with mild Alzheimer's Disease (AD). Other objectives are to assess the safety/tolerability of SSR180711C in patients with mild AD.

Terminated7 enrollment criteria

Mifepristone as Adjunctive Therapy in Alzheimer's Disease

Alzheimer's Disease

The purpose of this study is to evaluate the effects of C-1073 (Mifepristone) on cognition in patients with Alzheimer's disease (AD) who are also taking an acetylcholinesterase inhibitor (Aricept, Exelon or Reminyl).

Terminated61 enrollment criteria
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