cNEP for the Treatment of Obstructive Sleep Apnea
Sleep ApneaObstructiveThe purpose of this study is to determine whether cNEP (continuous positive external pressure) is effective in treating obstructive sleep apnea
AutoSet for Her Clinical Trial Protocol
Obstructive Sleep ApneaThe purpose of this study is to assess the efficacy and user preference of the Newport AutoSet for Her in female obstructive sleep apnea (OSA) patients. Efficacy will be evaluated by comparing the apnea and hypopnea index (AHI) and oxygen desaturation index (ODI) of the Newport AutoSet for Her algorithm to a standard algorithm. User preference will be evaluated by subjective feedback relating to comfort, ease of falling asleep, sleep disturbance and feeling of being refreshed.
Respicardia, Inc. Pivotal Trial of the remedē System
Sleep ApneaCentral2 moreThe primary purpose of this prospective, multicenter, randomized trial is to evaluate the safety and effectiveness of therapy delivered by the remedē® system in subjects with moderate to severe central sleep apnea and optimal medical management, compared to outcomes in randomized control subjects receiving optimal medical management and implanted but inactive remedē® systems.
Osteopathy and Obstructive Sleep Apnea Syndrome II
Obstructive Sleep Apnea SyndromeThe main objective is to evaluate an osteopathic compression of pterygopalatine node in healthy subjects and patients suffering from obstructive apnea syndrome (OSA).
The Effect of Continuous Positive Airway Pressure on Diastolic Function in Patients With Obstructive...
Obstructive Sleep ApneaThe association of obstructive sleep apnea (OSA) and cardiac diastolic dysfunction have been reported, and improvement of diastolic function after continuous positive airway pressure (CPAP) in OSA patients was observed. However, more detailed analysis of diastolic function by supine bicycle exercise echocardiography is lacking. The investigators hypothesized that 3 months of CPAP therapy in OSA patients will significantly improve diastolic functional parameters measured by exercise stress echocardiography. Patients with severe OSA (Apnea-hypopnea index > 30) will be included in this study, and randomized to CPAP versus sham-CPAP group by 1:1 ratio. Supine bicycle exercise echocardiography, pulse wave velocity, 24 hours ambulatory blood pressure (BP), central BP will be checked before and after CPAP therapy and parameters will be compared.
PAC-IC-SAOS Obstructive Sleep Apnea Syndrome and Ventricular Function
Heart FailureArteriosclerosis of Coronary Artery Bypass Graft or Other Coronary Reperfusion2 moreThe aim of this clinical trial is to evaluate the effect of obstructive sleep apnea syndrome (OSAS) treatment in heart failure patients following coronary artery bypass graft (CABG) surgery or other coronary reperfusion.
Safety and Efficacy Study of Dronabinol to Treat Obstructive Sleep Apnea
Sleep ApneaObstructiveThis is a proof of concept study to determine the safety and efficacy of dronabinol for the treatment of obstructive sleep apnea syndrome (OSA).
Transcend Auto Clinical Evaluation
Obstructive Sleep ApneaThe purpose of this study is to determine whether the Transcend Auto is as effective in treating obstructive sleep apnea as another device that is already on the market.
Intensive Versus Standard Follow up to Improve Continuous Positive Airway Pressure (CPAP) Compliance...
Sleep ApneaThe purpose of this study was to compare the effects on sleepiness, quality of life, depression, hospitalization and deaths rate, of intensive vs standard interventions, on CPAP adherence, 2 years after CPAP initiation.
Effect of CPAP Treatment in Women With Moderate-to-severe OSA.
Obstructive Sleep ApneaThe purpose of this study is to determine whether Continuous Positive Airways Pressure (CPAP) improves quality of life, cardiovascular (blood pressure) and metabolic profile (glucose and lipid metabolism) in females with moderate-to-severe Obstructive Sleep Apnea (OSA).