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Active clinical trials for "Sleep Apnea, Obstructive"

Results 131-140 of 1815

A Study of Danavorexton in People With Obstructive Sleep Apnea After General Anesthesia for Abdominal...

Sleep Apnea

The main aim is to see if danavorexton can help improve people's breathing in the recovery room after abdominal surgery.

Recruiting16 enrollment criteria

Use of Intraoral Suction and Its Effects on Obstructive Sleep Apnea

Obstructive Sleep Apnea of Adult

To learn whether stabilization of the tongue using intraoral suction is tolerable and what effects this approach has on sleep parameters in obstructive sleep apnea.

Recruiting15 enrollment criteria

A Mindfulness-Based Intervention to Improve CPAP

Obstructive Sleep Apnea (Moderate to Severe)Obstructive Sleep Apnea

The main purpose of this study is to assess the effectiveness of a mindfulness-based intervention in improving CPAP use compared to online peer support

Recruiting8 enrollment criteria

Ansa Cervicalis and Hypoglossal Nerve Stimulation in OSA

Obstructive Sleep Apnea

Polysomnography (PSG) and drug-induced sleep endoscopy (DISE) are widely used diagnostic studies for assessing obstructive sleep apnea (OSA) severity and collapse patterns of the upper airway anatomy during sleep. Hypoglossal nerve stimulation (HNS) therapy for obstructive sleep apnea suffers from variable response at the level of the soft palate. The Investigators propose a study examining the physiologic effect of ansa cervicalis stimulation (ACS) alone and in combination with HNS during PSG and DISE.

Recruiting7 enrollment criteria

Multimodal Remote Monitoring and Integrated Educational Program in OSA Patients Initiating Continuous...

Obstructive Sleep Apnea Syndrome

Continuous positive airway pressure (CPAP) is the first line therapy for Obstructive Sleep Apnea Syndrome (OSAS) but has limited impact for reducing cardio-metabolic risk. Combined treatment strategies including physical activity and weight loss management have emerged in association with CPAP. Patient's engagement might be supported by connected devices and smartphone applications measuring physical activity, blood pressure, weight and sleep duration. Data fusion of these parameters with CPAP-remote telemonitoring will allow personalized coaching and integrated care of OSAS with cardio-metabolic co-morbidities.

Recruiting24 enrollment criteria

Integrated Management of Chronic Respiratory Diseases

Sleep ApneaObstructive1 more

Chronic respiratory diseases such as obstructive sleep apnea syndrome (OSA) and chronic obstructive pulmonary disease (COPD) constitute a major public health problem, due to their high prevalence, but especially because of their cardiovascular and metabolic morbidity and mortality and the associated costs for the health system. The organization of long-term management of these diseases is now part of the e-health process, digital health with the use of massive "big data" generated by care and follow-up. Therapeutic patient education and the integration of connected objects will allow personalized therapeutic education support with interventions by local medical staff adapted to the needs of the patients. This will also allow to objectify the effect of treatments such as continuous positive airway pressure (CPAP) for OSA or non-invasive ventilation (NIV) and/or oxygen therapy for COPD, not only on the prevention of respiratory decompensation but also on cardiovascular and metabolic risk factors which are major elements of the prognosis. This project will therefore make it possible to demonstrate the feasibility and to deploy a multi-actor care pathway in the territory. The investigators propose a prospective clinical study, conducted at the Verdun Hospital, with the main objective of studying the evolution of the quality of life of patients with a chronic respiratory pathology, during an integrated management at home for 6 months. The secondary objectives: To study the evolution of the following parameters, before treatment (at inclusion) and after 6 months of integrated management: Treatment compliance (CPAP or NIV/oxygen therapy) Physical activity Weight Mean arterial pressure Oxygen saturation, heart rate and respiratory rate for COPD patients Severity of COPD for the patients concerned Daytime sleepiness Fatigue Patient acceptability of the use of connected objects To analyze the trajectories of the measures collected throughout the integrated management to identify specific profiles. To analyze the daily data of the different connected objects and treatments with regard to the patients' profiles (according to age, gender, comorbidities, OSA or COPD group).

Recruiting16 enrollment criteria

The Impact of Interscalene Block on Sleep Disordered Breathing

Sleep Disordered BreathingObstructive Sleep Apnea

This is a randomized controlled trial evaluating the impact of interscalene block on worsening of upper airway collapse in sleep disordered breathing for patients undergoing ambulatory shoulder surgery.

Recruiting9 enrollment criteria

Effect on Sleep of Surgical Treatment of Severe Nasal Obstruction

Sleep ApneaObstructive Sleep Apnea1 more

The aim of the study is to evaluate the effect of nasal desobstruction surgery (septoplasty, septorhinoplasty or total ethmoidectomy) on sleep quality, assessed by the variation of the Wake after sleep onset (WASO), in patients presenting with sleep disorders and severe nasal obstruction.

Recruiting20 enrollment criteria

OSA-18 in Children With Mild Obstructive Sleep Apnea: Can it be a Helpful Decision Making Tool?...

ApneaObstructive Sleep1 more

The concept is a novel research idea that incorporates the potential impact of patient quality of life (QOL) on decision-making for treatment of mild obstructive sleep apnea (OSA). Our hypothesis is that in children with mild OSA there is significant conflict with parental decision-making; in the absence of significant sleep apnea, there is limited research regarding comparative efficacy of various treatment options. The impact of a QOL questionnaire can be a significant deciding factor and may help guide management decisions in such situations.

Recruiting5 enrollment criteria

Functional Magnetic Resonance Imaging in Patients With Obstructive Sleep Apnea Syndrome

Obstructive Sleep Apnea Syndrome

The obstructive sleep apnea syndrome (OSAS) involves recurrent sleep-related upper airways (UA) collapse. UA mechanical properties and neural control are altered, imposing a mechanical load on inspiration. UA collapse does not occur during wakefulness, hence arousal-dependent compensation. Experimental inspiratory loading in normal subjects elicits respiratory-related cortical activity during wakefulness. The objective of this study is to test whether awake OSAS patients would exhibit a similar cortical activity. Whether or not such cortical compensatory mechanisms have cognitive consequences would be also analyze.

Recruiting25 enrollment criteria
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