search

Active clinical trials for "Sleepiness"

Results 1-10 of 152

Clinical Trial of Solriamfetol for Excessive Sleepiness Related to Shift Work Disorder

Excessive SleepinessShift-work Disorder

In this research study the investigators want to learn more about whether the medication Solriamfetol improves daytime sleepiness in workers who start work at very early times (between 3 and 6am).

Recruiting38 enrollment criteria

A Study to Assess the Efficacy and Safety of AXS-12 (Reboxetine) in Patients With Narcolepsy

NarcolepsyCataplexy1 more

This study is a multi-center, double-blind, placebo-controlled, randomized Phase 3 trial to assess the safety and efficacy of AXS-12 in narcoleptic subjects with cataplexy and excessive daytime sleepiness (EDS).

Recruiting5 enrollment criteria

Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive...

Sleep Apnea SyndromeObstructive Sleep Apnea7 more

Obstructive sleep apnea (OSA) and Chronic Obstructive Pulmonary Disease (COPD) are highly prevalent chronic respiratory diseases in the Veteran population. OSA co-occurring with COPD, known as Overlap Syndrome (OVS), is a complex chronic medical condition associated with grave consequences. OVS is highly prevalent in Veterans. Veterans with OVS may be at increased risk for cognitive deficits, poor sleep quality as well as a reduced quality of life (QoL). The overall objective is to study the effects of positive airway pressure therapy on clinical outcomes in patients with OVS.

Recruiting22 enrollment criteria

A Study to Investigate the Effect of XYWAV on Sleepiness, Polysomnography, and Functional Outcomes...

Idiopathic HypersomniaNarcolepsy

This study will assess the safety and efficacy of JZP258 (XYWAV) on sleepiness, polysomnography, and functional outcomes in patients with idiopathic hypersomnia (IH) or narcolepsy.

Recruiting10 enrollment criteria

Impact of Bright Light Therapy on Prader-Willi Syndrome

Prader-Willi SyndromeExcessive Daytime Sleepiness4 more

This is a placebo controlled clinical trial to assess the utility of light therapy as a sufficient treatment for excessive daytime sleepiness in patients with Prader-Willi Syndrome

Recruiting5 enrollment criteria

A Study to Assess the Long-term Efficacy and Safety of AXS-12 (Reboxetine) in Subjects With Narcolepsy...

NarcolepsyCataplexy1 more

This study will evaluate the long-term efficacy and safety of AXS-12 in narcoleptic subjects with cataplexy and excessive daytime sleepiness (EDS).

Enrolling by invitation3 enrollment criteria

Voice Biomarkers to Predict Excessive Daytime Sleepiness

Sleep Deprivation

This study aims at measuring the impact of a night of sleep deprivation over the vocal characteristics of healthy subjects.To do so, the subjects takes a Multiple Sleep Latency Test (MSLT) the day after a night of total sleep deprivation (or a supervised normal night for the control subjects). Before each iteration of the MSLT, the subjects are recorded during the reading of a text and fill three medical questionnaires : Karolinska Sleepiness Scale (KSS), Visual Analogue Scale for Fatigue (VAS-F) and Visual Analogue Scale for Anxiety (VAS-A), allowing to link variations of vocal markers to the variations of these measures.

Recruiting38 enrollment criteria

Effects of Chronobiology-guided Lifestyle Interventions on Insomnia Severity, Cognitive Performance,...

Circadian Rhythm Sleep Disorder

Poor sleep is closely related to circadian misalignment; shift workers often experience shift work disorder characterized by excessive sleepiness and recurrent shift work schedules-associated insomnia. This study aims to examine the effects of a program of chronobiology-guided lifestyle interventions (CGLI) on insomnia severity, cognitive performance (psychomotor vigilance and processing speed), and sleepiness in female nurses undertaking rotating-shift work.

Recruiting9 enrollment criteria

Lifestyle Coaching for Fatigue Mitigation in Emergency Medicine Residents

LifestyleHealthy6 more

The purpose of this study is to determine whether personalized lifestyle coaching minimizes the negative impact of circadian disruption on performance and recovery in emergency medicine physician trainees during night shifts.

Recruiting4 enrollment criteria

Safety and Efficacy of Pitolisant on Excessive Daytime Sleepiness and Other Non-Muscular Symptoms...

Myotonic Dystrophy 1Excessive Daytime Sleepiness

The primary objective of this study is to evaluate the safety and efficacy of pitolisant compared with placebo in treating excessive daytime sleepiness (EDS) in patients with Myotonic Dystrophy Type 1 ages 18 to 65 years. The secondary objectives of this study are to assess the impact of pitolisant on fatigue, cognitive function and the burden of disease along with assessing the long-term safety and effectiveness of pitolisant in patients with Myotonic Dystrophy Type 1 ages 18 to 65 years.

Active45 enrollment criteria
12...16

Need Help? Contact our team!


We'll reach out to this number within 24 hrs