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Active clinical trials for "Spondylolisthesis"

Results 41-50 of 211

Survivorship of Decompression Alone Vs Decomp With Fusion in DLS and LCS

Lumbar Spondylolisthesis Involving L4-L5

There has been a long-standing controversy on the operative treatment of Degenerative Lumbar Spondylolisthesis (DLS) with Lumbar Canal Stenosis (LCS), especially whether the addition of fusion to decompression is necessary. Many believe that decompression alone (D) by either using midline preserving fenestration techniques (fenestration by laminotomy and medial facetectomy) or with a spinous process osteotomy (SPO) is enough for treatment of patients with DLS while others believe that a fusion (D+F) should be added in all cases. The study aims to determine if decompression alone performs better or worse in the long term than decompression with fusion in a large cohort of patients who have DLS with LCS. It also aims to determine if the decompression technique of midline-sparing fenestration or spinous process osteotomy make a difference to survival in cases of DLS with LCS.

Enrolling by invitation2 enrollment criteria

Advanced Materials Science in XLIF Study

Degenerative Disc DiseaseSpondylolisthesis

This study is being conducted to evaluate the clinical and radiographic outcomes of three different interbody implant types when used with cancellous allograft chips with BMA or cellular allograft in patients undergoing XLIF surgery. The study will evaluate success by comparing the rate of fusion, complications profile, and any relationships between clinical outcomes (pain and function) and radiographic outcomes (fusion rate) between the three implant groups.

Enrolling by invitation35 enrollment criteria

Modulus in XLIF Study

Degenerative Disc DiseaseDegenerative Spondylolisthesis1 more

The primary objective of this study is to evaluate the safety and performance of the Modulus 3D-printed titanium interbody implant in patients undergoing thoracic and/or lumbar XLIF as measured by reported complications, radiographic outcomes, and patient-reported outcomes.

Enrolling by invitation19 enrollment criteria

Pedicle Osteotomy for Stenosis Trial

Lumbar Spinal StenosisSpondylolisthesis2 more

This is a pivotal Randomized Clinical trial to compare the safety and effectiveness of the Pedicle Lengthening Osteotomy Procedure with implantation of the Altum® Device to open surgical decompression and Transforaminal Lumbar Interbody Fusion (TLIF) in patients with symptomatic, one or two level lumbar spinal stenosis (LSS) and one level grade I degenerative spondylolisthesis requiring surgical treatment.

Suspended36 enrollment criteria

Lumbar Interbody Implant Study

Degenerative Disc DiseaseDegenerative Spondylolisthesis3 more

The objective of this study is to evaluate the safety and performance of NuVasive interbody implants when used during thoracic and/or lumbar spine surgery as measured by reported complications, radiographic outcomes, and patient-reported outcomes. This study is being undertaken to identify possible residual risks and to clarify mid- to long-term clinical performance that may affect the benefit/risk ratios of these interbody implants.

Enrolling by invitation42 enrollment criteria

PMCF Study on the Safety and Performance of CESPACE 3D

Degenerative InstabilitySpondylolisthesis2 more

Prospective, pure data collection of all CeSPACE 3D patients in selected centers (not interventional, multicenter)

Recruiting5 enrollment criteria

The Spine PROMCO Study

Lumbar Disc HerniationSpondylolisthesis1 more

Our primary objective is to design a cohort to determine the treatment outcome of different surgical interventions of the degenerative lumbar spine highlighting the expediency and value of the current surgical treatment program.

Recruiting10 enrollment criteria

Intraoperative Monitoring for the Lateral Lumbar Interbody Fusion Procedure

Intervertebral Disc DegenerationStenosis4 more

This study is designed to evaluate the clinical utility of a known intraoperative neuromonitoring modality (SSEP) using saphenous nerve as the site of stimulation to identify changes to the lumbar nerves which may be at risk during the lateral lumbar interbody fusion (LLIF) procedure.

Recruiting9 enrollment criteria

Thoracic-Lumbar Arthrodesis- Implanet Jazz

SpondylolisthesisSpinal Stenosis1 more

Establish a data repository of patients who have undergone single, two-, or three-level lumbar instrumented arthrodesis procedures supplemented by the Implanet Jazz System.

Recruiting3 enrollment criteria

Studying Melatonin and Recovery in Teens

Juvenile; ScoliosisScoliosis Idiopathic4 more

The goal of this feasibility clinical trial is to learn if melatonin can help teens having spinal fusion surgery by promoting healthy sleep. Melatonin is available as a dietary supplement that may be effective in promoting longer, higher quality sleep. This study will assess the feasibility and acceptability of melatonin for teens undergoing spinal fusion surgery, as well as determine optimal measured outcomes (sleep, pain, health-related quality of life) at short- and long-term follow-up.

Not yet recruiting20 enrollment criteria
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