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Active clinical trials for "Spondylolisthesis"

Results 81-90 of 211

Comparison of nanOss Bioactive With Autograft and Bone Marrow Aspirate to Autograft in the Posterolateral...

Degenerative Disc DiseaseSpinal Stenosis1 more

nanOss Bioactive is approved for use in the U.S. The purpose of this study is to compare fusion results in the posterolateral spine using nanOss Bioactive mixed with autograft bone and bone marrow aspirate (BMA) on one side and autograft alone on the opposite side of the treated level(s). It is hypothesized that the use of nanOss Bioactive will result in fusion at 12 months, with CT evidence of bridging trabecular bone, less than 3mm of translational motion, and less than 5 degrees of angular motion.

Completed29 enrollment criteria

Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed...

Low Back PainLeg Pain2 more

The purpose of this multi-center, randomized, clinical study is to establish the safety and effectiveness of the TOPS™ System, used following decompression, in the treatment of lower back and leg pain with, or without spinal claudication, that results from moderate or severe lumbar spinal stenosis at one vertebral level between L3 and L5.

Completed29 enrollment criteria

Lumbar Fusion With Nexxt Spine 3D-Printed Titanium Interbody Cages

Lumbar Degenerative Disc DiseaseLumbar Spinal Stenosis3 more

The purpose of this randomized controlled trial is to assess and compare radiographic and clinical outcomes in patients who are to undergo combined interbody/posterolateral lumbar fusion procedures, supplemented with pedicle screw instrumentation, using one of the following interbody cages; the Nexxt Spine Nexxt MatrixxTM 3D-printed titanium cage or the HonourTM poly-ether-ether-ketone cage.

Completed18 enrollment criteria

Natural Matrix Protein™ (NMP™) Fibers in Cervical and Lumbar Interbody Fusion

Degenerative Disc DiseaseDegenerative Spondylolisthesis1 more

The aim of this study is to evaluate the effectiveness and safety of Natural Matrix Protein™ (NMP™) fibers when used in cervical or lumbar interbody fusion in patients with degenerative disc disease (DDD), spinal stenosis, spondylolisthesis undergoing cervical or lumbar interbody spine fusion at no more than 3 adjacent levels.

Not yet recruiting9 enrollment criteria

Safety and Efficacy of the CarboFix Pedicle Screw System

Degenerative Disc DiseaseSpondylolisthesis3 more

The purpose of this study is to evaluate the safety and efficacy of CarboFix' Pedicle Screw System in the lumbar spine.

Completed26 enrollment criteria

Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion

Degenerative Disc DiseaseDegenerative Spondylolisthesis1 more

The purpose of this study is to evaluate the safety and preliminary efficacy of NeoFuse in subjects with a diagnosis of degenerative disc disease (DDD) in 1 or 2 adjacent vertebral levels between L1 and S1. All subjects in this study will undergo interbody fusion via Transforaminal Lumbar Interbody Fusion (TLIF) or Posterior Lumbar Interbody Fusion (PLIF) procedures with Food and Drug Administration (FDA) approved/cleared supplemental posterior instrumentation.

Completed19 enrollment criteria

Spine Research With Roentgen Stereophotogrammetric Analysis

SpondylolisthesisDegenerative Lumbar Disc Disease1 more

The purpose of this study is to gather information on the effectiveness of a new spine implant for patients who require spinal fusion surgery. Based on this information, we hope to create a standard of good performance, or benchmark, against which future studies on this spine implant can be compared. By creating this benchmark we hope to improve care for patients who require spinal fusion surgery.

Completed18 enrollment criteria

Incidence of Lumbar Spondylolisthesis in Patients Candidate for TKR

Lumbar Spondylolisthesis

This study aims to detect the incidence of spondylolisthesis in patients candidate for Total knee replacement (TKR) and to investigate the effect of TKR on the course of low back pain.

Not yet recruiting6 enrollment criteria

The Addition of a Pilates Program for Short-Term Improvements in Patients With Spondylolysis or...

SpondylolisthesisSpondylolysis1 more

Purpose: To determine the effectiveness of an augmented Pilates program, when combined to a multimodal strengthening program, for patients under the age of 21, who have spondylolysis and/or spondylolisthesis. Significance of the topic: Spondylolysis and spondylolisthesis are often diagnosed in children and adolescents presenting with low back pain. A randomized, clinical trial, test-retest design, with a 3 week and 6 week assessment with functional performance test measures, exercise logs, adherence scale for patient and parent perception, and outcome measures (Global rating of change (GROC) and Modified Oswestry Disability Index (ODI)). This study will attempt to obtain at least 120 subjects that will be randomized into two groups: bracing and a general strengthening program vs. bracing and a Pilates/motor learning program combined with a general strengthening program. This study will begin with an initial examination and continue with treatment sessions 2x/week for 6 weeks. A follow up phone call will be conducted at 3 months after completing the 6-week protocol. The follow up phone call will be an oral conducted GROC and ODI outcome measures.

Completed9 enrollment criteria

Lumbar Stabilization Exercises vs Flexor Exercises in Degenerative Spondylolisthesis

Degenerative SpondylolisthesisChronic Low Back Pain

The purpose of this study is to compare the effectiveness of pain control and functional improvement in patients with degenerative spondylolisthesis treated with "lumbar stabilization exercises" vs "flexor exercises (williams exercises)"

Completed10 enrollment criteria
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