Cost Effectiveness if Primary PCI Versus Thrombolytic Therapy in Acute STEMI in Assiut University...
ST Elevation Myocardial InfarctionCost effectiveness between PPCI and thrombolytic therapy in STEMI patients without contraindications
Non Culprit Functional Evaluation With 3D Angio QFR in STEMI PCI Procedure
STEMI - ST Elevation Myocardial InfarctionPercutaneous Coronary Intervention1 moreReliability of 3D angio QFR functional evaluation of all non culprit lesions >50% in STEMI patients during first acute procedure
Analysis of the Microbiota and STEMI
STEMIDiabetes Mellitus1 moreHyperglycemia is a common finding in patients diagnosed with acute coronary syndrome (ACS), and an independent predictor of mortality in patients with and without diabetes. Though percutaneous coronary intervention (PCI) is the cornerstone of ST-segment elevation myocardial infarction (STEMI), the incidence of heart failure, re-infarction and death in hyperglycemic patients remains significant, with a mortality of more than 40% one year after the event. In these STEMI patients dual anti-aggregation therapy is currently the gold standard after PCI, but bleeding phenomena, and therapeutic resistance may reduce their therapeutic efficacy. Therefore, it is likely that the individual response to the dual anti-aggregation therapy, and the hyperglycemic stress, may influence resistance mechanisms, and/or lead to an increase in pharmacological functional deactivation by the microbiotic flora. The term microbiota indicates the totality of the genomes of microorganisms that reside in an ecological niche, and which constitute the "human microbiota". In this context, the analysis of the faecal microbiota before PCI, at hospital discharge and at follow-up, could be considered useful for identifying hyperglycaemic patients with alteration of metabolic-oxidative processes, and pro-thrombotic correlates with worse post procedural prognosis. Therefore, the analysis of faecal microbiota during the STEMI event could theoretically identify hyperglycemic patients with excessive inflammatory and oxidative tone caused by hyperglycemia, conditioning resistance to double anti-aggregation therapy and coronary stenting, and conditioning pro-thrombotic phenomena after coronary reperfusion by PCI. Therefore, authors will conduct a study to analyze the microbiota in patients with acute hyperglycaemic and normoglycemic coronary syndrome. The primary objective of this study will be to evaluate any changes in the microbiota and its activity on faecal material taken before PCI, and after 6 and 12 months in patients with hyperglycemic STEMI, and also evaluate if the changes in the microbiota can be related to the 12-month prognosis.
CorPath GRX STEMI Study
STEMI - ST Elevation Myocardial InfarctionCADThis study will evaluate the performance of the CorPath GRX System in Robotic Primary PCI (RPPCI) in the treatment of ST-elevated myocardial infarction (STEMI).
Impact of Stent Length and Diameter on Patients Undergoing Primary PCI
ST-segment Elevation Myocardial Infarction (STEMI)The goal of the study is to evaluate the Impact of coronary stent length and/or diameter in patients with ST segment myocardial infarction undergoing primary PCI, on Short term clinical outcomes.
Ultrasound Beams as an Adjunct to Reperfusion Therapy in STEMI
Myocardial InfarctionST Elevation Myocardial InfarctionSuccessfully perfused STEMI patients will receive routine transthoracic echocardiography qid for 4 days or placebo. Myocardial function and infarct size will be evaluated at 3 and 6 months.
Differential Effects of Lipids on Cardiovascular Diseases: A CALIBER Study
Stable AnginaUnstable Angina3 moreThe role of lipids as risk factors for cardiovascular events is well-documented, although events studied have largely been broad classes without specific detail. This study will examine a more refined set of endpoints.
Brasilia Heart Study
ST-Elevation Myocardial InfarctionBHS is a cohort study of consecutive myocardial infarction (MI) patients admitted within the first 24 hours of symptoms and has been ongoing since May of 2006. The purpose of this study is to assess for possible markers for increased risk after MI.
Predictive Value of CHA2DS2-VASC Score and Contrast Volume to Creatinine Clearance Ratio in Relation...
Contrast-induced Nephropathyall patient presented with ST elevated myocardial infarction and underwent PPCI will be calculated with CHA2DS2-VASC score and contrast volume / creatinine clearance as apredictive value for Contrast induced nephropathy and the predictive value of these scores will be compared with the approved predictive value of MEHRAN score which is also will be calculated to every patient .
Combination With Treg Levels and CMR to Assess the Severity and Prognosis of Reperfusion Injury...
STEMI - ST Elevation Myocardial InfarctionReperfusion Injury1 moreThis study aims to determine whether combination with regulatory T cell (Treg) levels and cardiac magnetic resonance imaging (CMR) are predictive of the severity of reperfusion injury following myocardial infarction and the prognosis in STEMI patients receiving primary percutaneous coronary intervention (PPCI).