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Active clinical trials for "ST Elevation Myocardial Infarction"

Results 411-420 of 510

The Relationship Between MPV,PDW,PFT and ST Segment Resolution in STEMI Patients Treated With Thrombolytic...

STEMI - ST Elevation Myocardial Infarction

The relationship between admission MPV, PDW, platelet function test and ST-segment resolution in STEMI patients treated with either thrombolytic therapy or primary percutaneous coronary intervention The relationship between admission MPV, PDW, platelet function test and high thrombus burden & post-PCI Thrombolysis In Myocardial Infarction (TIMI) flow of infarct related artery in STEMI patients treated with primary percutaneous coronary intervention

Withdrawn9 enrollment criteria

Observational Registry to Evaluate Real World Usage of PiCSO Impulse System in STEMI Patients as...

STEMI - ST Elevation Myocardial InfarctionAnterior MI

A prospective, multicenter, single-arm, open label registry of commercially treated patients with PiCSO Impulse System.

Withdrawn18 enrollment criteria

Acute Coronary Syndrome Sri Lanka Audit Project

Acute Coronary SyndromeUnstable Angina2 more

ACSSLAP is the first island wide audit project in Sri Lanka on ACS.

Withdrawn5 enrollment criteria

Association Between Plasma Melatonin and No-reflow

ST-segment Elevation Myocardial Infarction

ST-segment elevation myocardial infarction (STEMI) is an acute manifestation of coronary heart disease, remaining a frequent cause of death. A better understanding of risk factors and pathogenic mechanisms underlying STEMI may help improve the prognosis and life quality of these patients. Melatonin is the chief indoleamine produced by the pineal gland, and a well-known antioxidant and free radical scavenger. Basic studies have showed that melatonin is associated with myocardial infarction and heart failure. However, no study has evaluated whether melatonin is associated with adverse clinical outcomes in STEMI patients.

Completed2 enrollment criteria

The Impact of Post Stenting Balloon Dilatation on Coronary Microcirculation in STEMI Patients Undergoing...

ST-elevation Myocardial Infarction (STEMI)

This study aims to assess the impact of NC balloon post-dilatation on coronary microcirculation in patients with ST segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI).

Completed18 enrollment criteria

Platelet Function in Resuscitated Patients

Acute ST Segment Elevation Myocardial Infarction

Approx. 65% of resuscitated patients at the intensive care unit for internal medicine are due to myocardial infarction. Almost all patients are initially diagnosed and treated in the cath lab. Therapy usually consists of one or more stent implantations. After implantation of a coronary stent, dual platelet inhibition is necessary for 12 months. Insufficient platelet inhibition causes an pronounced increase in risk of stent thrombosis. Therefore, knowledge of the individual platelet function is valuable. Several factors potentially promote a delayed or reduced mode of action of platelet function inhibitors in resuscitated patients: oral administration is impossible and medication needs to be administered via a gastric line. gastric absorption is delayed after resuscitation according to current guidelines patients are treated with therapeutic hypothermia. Including the time of rewarming cooling period is ~48h

Completed5 enrollment criteria

10-Years Follow-up of the EXAMINATION Trial

Myocardial InfarctionST Elevation Myocardial Infarction5 more

The EXAMINATION trial was a superiority trial that compared everolimus-eluting stents (EES) versus bare-metal stents (BMS) in an all-comer ST-segment elevation myocardial infarction (STEMI) population. The patient-oriented endpoint was not superior at 1-year, but it was at 5-year. However, very-long term follow-up is unknown. The study had an independent Clinical event Committee (CEC). All events were adjudicated by an independent clinical committee, according to the Academic Research Consortium 1.

Completed2 enrollment criteria

Myocardial Oedema in ST Segment Elevation Myocardial Infarction Myocardial

ST Segment Elevation Myocardial InfarctionMyocardial Oedema

Cardiac magnetic resonance imaging (CMR) is a non invasive technique used to obtain functional and anatomical information on the heart. Several CMR parameters measured after primary percutaneous coronary intervention (PPCI) have been shown to have prognostic value and are increasingly being used as surrogate endpoints in clinical trials. Myocardial oedema is a prognostic indicator following myocardial infarction1. Myocardial salvage is calculated as the myocardial oedema minus infarct size; this again is a prognostic indicator following STEMI. However, myocardial oedema imaging is controversial. There are multiple sequences available, with no standardisation of sequences used to assess this surrogate endpoint. The investigators propose to conduct a study to measure the myocardial oedema by all available techniques to determine the agreement between these methods.

Completed6 enrollment criteria

Microvascular Dysfunction in Acute Myocardial Infarction (AMI) and Its Relation to Outcome

ST Segment Elevation Myocardial Infarction

The purpose of this study is first to evaluate absolute myocardial blood flow and resistance over time in the acute and sub-acute phase of myocardial infarction and second, to correlate these parameters to preservation of left ventricular function and long-term outcome.

Completed13 enrollment criteria

Monocytosis and Culprit Vessel in STEMI Patients

STEMI

Increased white blood cell count at the onset of an acute ST elevation myocardial infarction has been shown to be associated of increased incidence of heart failure and mortality. Now monocytes which are a subset of white blood cells may have a prognostic value for patients presenting with acute ST segment elevation myocardial infarction. A monocyte count of greater than 800/mm3 following acute myocardial infarction has been shown to be associated with increased incidence of left ventricular dysfunction. The investigators study would retrospectively collect data on patients with ST elevation myocardial infarction, looking for an association between high monocyte count and the culprit vessel causing the myocardial infarction. The investigators would also investigate whether monocytosis would be a marker of poor prognosis.

Completed2 enrollment criteria
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