Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children,...
Methicillin-Resistant Staphylococcus AureusBacterial Infections1 moreTo determine the safety and descriptive efficacy of dalbavancin for the treatment of acute bacterial skin and skin structure infections in children, aged birth to 17 years (inclusive), known or suspected to be caused by susceptible Gram-positive organisms, including methicillin-resistant strains of Staphylococcus aureus.
First Time in Man Trial for Friulimicin B
Community Acquired PneumoniaStaphylococcal Skin InfectionsThe purpose of this study is to study the safety of single doses and multiple doses of Friulimicin B in healthy volunteers. The level of Friulimicin B will be measured in the subjects blood and urine. One part of the study will assess if Friulimicin B in the plasma of subjects has activity against bacteria.
Safety and Efficacy of Daptomycin for the Treatment of Complicated Skin and Skin-structure Infections...
Staphylococcal Skin InfectionsThis study will evaluate the safety and efficacy of daptomycin against complicated skin and skin-structure infections in adults
Comparison of Cephalexin Versus Clindamycin for Suspected CA-MRSA Skin Infections
Staphylococcal InfectionAbscess2 moreThe purpose of this study is to help define the role of antibiotics in the treatment of pediatric skin infections caused by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA). The investigators hypothesize that treatment with cephalexin, a penicillin-like antibiotic to which CA-MRSA would be expected to be resistant, does not result in poorer outcomes than treatment with clindamycin, an antibiotic to which CA-MRSA is most often susceptible.
Comparison of Telavancin and Vancomycin for Complicated Skin and Skin Structure Infections With...
Staphylococcal Skin InfectionStudy 0018 (NCT00107978) compares the safety and effectiveness of an investigational drug, telavancin, and an approved drug, vancomycin, for the treatment of complicated skin and skin structure infections.
Ceftobiprole in the Treatment of Resistant Staphylococcus Aureus Skin and Skin Structure Infections...
Skin DiseasesInfectious3 moreThe purpose of this study is to compare the clinical cure rate of ceftobiprole medocaril versus a comparator in the treatment of patients with complicated skin and skin structure infections. The study will also characterize the safety and tolerability of treatment with ceftobiprole medocaril in patients with complicated skin and skin structure infections.
Safety and Efficacy Study of a Fluoroquinolone to Treat Complicated Skin Infections
Skin Structure InfectionsBacterial Skin Diseases1 moreThe purpose of this study is to assess the efficacy, safety and tolerability of RX-3341 (delafloxacin), a fluoroquinolone, versus tigecycline, a glycylcycline antibacterial drug, in the treatment of complicated skin and skin structure infections.
Safety and Efficacy Study of Oxazolidinones to Treat Uncomplicated Skin Infections
Infectious Skin DiseasesBacterial Skin Diseases3 moreThe purpose of this study is to assess the efficacy, safety and tolerability of RX-1741, an oxazolidinone, versus linezolid, another oxazolidinone, in the treatment of uncomplicated skin and skin structure infections
Staphylococcus Aureus Decolonization Study
Staphylococcal Skin InfectionsAbscesses3 moreThe purpose of this study is to determine whether measures to eliminate the Staph germ from the skin of the index patient (with a special ointment and soap) are more effective when performed by everyone in the household rather than the patient alone, and whether these methods are effective in preventing future Staph infections. The investigators hypothesize that there will be a greater number of households who are successful in eradicating the staph germ from the index patient when all members of the household participate than households where only the index patient is treated.
Ceftobiprole in the Treatment of Resistant Staphylococcus Aureus Skin and Skin Structure Infections...
Skin DiseasesInfectious3 moreThe purpose of this study is to compare the clinical cure rate of ceftobiprole medocaril versus a comparator in the treatment of patients with complicated skin and skin structure infections.